On Chronic Liver Failure
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CLINICAL_TRIALS research · 2018-06-06Clinical Trial Update: Exploring Biomarkers Predicting the Outcome of Acute-on-chronic Liver Failure
A completed clinical trial update describing research into biomarkers that predict outcomes in acute-on-chronic liver failure, with relevanc…
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CLINICAL_TRIALS trial_result · 2017-11-28Clinical Trial Update: Incidence And Outcome Of Paracentesis Induced Circulatory Dysfunction In Acute-On-Chronic Liver Failure. [NA]
This clinical trial update examines how often paracentesis-induced circulatory dysfunction occurs and what outcomes occur in patients with a…
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CLINICAL_TRIALS withdrawal · 2017-11-28Clinical Trial Update: To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis.
This ClinicalTrials.gov entry indicates that the study evaluating the clinical course and organ failure in severe acute hepatitis with and w…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: To Compare the Response Rate of Noradrenaline vs. Terlipressin in Hepatorenal Syndrome in Patients With Acute on Chronic Liver Failure [NA]
Completed clinical trial comparing noradrenaline (norepinephrine) versus terlipressin for the response rate in hepatorenal syndrome among pa…
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CLINICAL_TRIALS research · 2017-11-17Clinical Trial Update: Early Versus Late CRRT in ACLF Patients With Septic Shock and AKI [NA]
This clinical trial update discusses a study comparing early versus late continuous renal replacement therapy in patients with acute-on-chro…
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: Efficacy of Granulocyte Colony-stimulating Factor and Erythropoetin for Patients With Acute-on-chronic Liver Failure [Phase 3]
Phase 3 trial evaluating granulocyte colony-stimulating factor and erythropoietin for acute-on-chronic liver failure has completed, with eff…
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CLINICAL_TRIALS research · 2016-06-24Clinical Trial Update: UC-MSC Infusion for HBV-Related Acute-on-Chronic Liver Failure [Phase 2]
Phase 2 clinical trial investigating infusion of umbilical cord-derived mesenchymal stem cells (UC-MSC) for HBV-related acute-on-chronic liv…
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CLINICAL_TRIALS research · 2016-05-02Clinical Trial Update: Assessment of Coagulation Abnormalities in Acute on Chronic Liver Failure Patients Using Thromboelastography [Phase 4]
Phase 4 clinical trial update evaluating coagulation abnormalities in patients with acute-on-chronic liver failure using thromboelastography…
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CLINICAL_TRIALS research · 2016-04-26Clinical Trial Update: A Trial of Ribavirin in Patients With ACLF Due to Hepatitis E Virus [Phase 2]
This clinical trial update describes a Phase 2 study evaluating ribavirin in patients with acute-on-chronic liver failure due to Hepatitis E…
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CLINICAL_TRIALS trial_result · 2016-04-11Clinical Trial Update: Pharmacokinetic and Pharmacodynamic Study of IDN-6556 in ACLF [Phase 2]
Phase 2 pharmacokinetic and pharmacodynamic study of IDN-6556 in acute liver failure conditions was terminated, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2015-09-29Clinical Trial Update: Role of 13C Methacetin Breath Test in Predicting Prognosis Among Patients With Acute or Acute on Chronic Liver Failure (ACLF). [NA]
A completed clinical trial evaluating whether the 13C methacetin breath test can predict prognosis in patients with acute liver failure and …
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CLINICAL_TRIALS trial_result · 2015-05-27Clinical Trial Update: Spectrum, Profile and Outcome of Infections in Patients With Cirrhosis and/ or Acute on Chronic Liver Failure
This clinical trial update characterizes infections in patients with cirrhosis and/or acute-on-chronic liver failure, detailing the spectrum…
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CLINICAL_TRIALS trial_result · 2015-02-25Clinical Trial Update: Single Pass Albumin Dialysis in Patients With Cirrhosis [Phase 1, Phase 2]
Clinical trial update indicating completion of Phase 1 and Phase 2 studies of Single Pass Albumin Dialysis in patients with cirrhosis and re…
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CLINICAL_TRIALS research · 2013-10-11Clinical Trial Update: Prognosis Scoring System for Acute-on-Chronic Liver Failure
A clinical trial update regarding a prognosis scoring system being studied for acute-on-chronic liver failure, sponsored by the Third Affili…
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CLINICAL_TRIALS research · 2013-06-04Clinical Trial Update: Evaluation of Role of Transient Elastography (Fibroscan) in Differentiating Patients of Acute Severe Viral Hepatitis and Acute on Chronic Liver Failure
This clinical trial evaluates whether transient elastography (Fibroscan) can differentiate between acute severe viral hepatitis and acute-on…
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CLINICAL_TRIALS research · 2013-04-08Clinical Trial Update: Study of the Model to Predict 3-month Mortality Risk of Acute-on-chronic Hepatitis B Liver Failure
This completed clinical trial evaluates a predictive model for 3-month mortality risk in patients with acute-on-chronic liver failure relate…
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CLINICAL_TRIALS trial_result · 2010-12-07Clinical Trial Update: The Efficacy and Safety of Entecavir Treatment of Patients With Acute on Chronic Hepatitis B Liver Failure [Phase 2]
Phase 2 trial assessing the efficacy and safety of entecavir in patients with acute-on-chronic hepatitis B–related liver failure.
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CLINICAL_TRIALS trial_result · 2010-02-24Clinical Trial Update: Randomized Controlled Trial of Tenofovir in Patients of Reactivation of Hepatitis B Presenting as Acute on Chronic Liver Failure [Phase 4]
A Phase 4 randomized trial evaluated Tenofovir for hepatitis B reactivation presenting as acute-on-chronic liver failure, and the study has …
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CLINICAL_TRIALS research · 2010-02-19Clinical Trial Update: Predictive Utility of DASIMAR as a Prognostic Biomarker in Acute-on-chronic Liver Failure (ACLF)
Clinical trial update assessing the predictive utility of the DASIMAR biomarker for prognosis in acute-on-chronic liver failure due to liver…
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CLINICAL_TRIALS research · 2009-12-21Clinical Trial Update: Granulocyte Colony Stimulating Factor(G-CSF) Therapy for Patients With ACLF [NA]
Clinical trial update on granulocyte colony-stimulating factor (G-CSF) therapy for patients with acute-on-chronic liver failure; current sta…