Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-06-24Clinical Trial Update: Differentiation Induction in Acute Myelogenous Leukemia [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial in acute myeloid leukemia sponsored by the University of Bergen has completed.
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CLINICAL_TRIALS trial_result · 2015-06-24Clinical Trial Update: A Study of Imatinib With Reinduction Chemotherapy Using Mitoxantrone, Etoposide and Cytarabine in Patients With Relapsed/Refractory C-kit Positive (AML) Acute Myeloid Leukemia [Phase 1, Phase 2]
A phase 1/2 study evaluating the combination of imatinib with reinduction chemotherapy (mitoxantrone, etoposide, cytarabine) in relapsed/ref…
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CLINICAL_TRIALS research · 2015-06-24Clinical Trial Update: Treatment of Acute Leukemia Relapse After Allotransplantation [Phase 1, Phase 2]
A clinical trial update describing a Phase 1/2 study for treating relapse of acute myeloid leukemia after allogeneic stem cell transplantati…
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CLINICAL_TRIALS trial_result · 2015-06-22Clinical Trial Update: Study Evaluating the Tolerance and Biological Activity of Oral Clioquinol in Patients With Relapsed or Refractory Hematological Malignancy [Phase 1]
Phase 1 clinical trial evaluating the safety, tolerability, and biological activity of oral clioquinol in patients with relapsed or refracto…
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CLINICAL_TRIALS trial_result · 2015-06-22Clinical Trial Update: Study Evaluating the Tolerance and Biologic Activity of Oral Ciclopirox Olamine in Patients With Relapsed or Refractory Hematologic Malignancy [Phase 1]
This Phase 1 clinical trial update reports the tolerance and biologic activity of oral ciclopirox olamine in patients with relapsed or refra…
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CLINICAL_TRIALS trial_result · 2015-06-22Clinical Trial Update: Safety and Efficacy Study of Nilotinib Combined With Mitoxantrone, Etoposide, and High-dose Cytarabine Induction Chemotherapy Followed by Consolidation for Patients With C-kit Positive Acute Myeloid Leukemia [Phase 1, Phase 2]
This terminated Phase 1/2 trial evaluated the safety and efficacy of adding nilotinib to a mitoxantrone, etoposide, and high-dose cytarabine…
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CLINICAL_TRIALS trial_result · 2015-06-19Clinical Trial Update: Cholecalciferol in Treating Patients With Acute Myeloid Leukemia Undergoing Intensive Induction Chemotherapy [Phase 2]
Phase 2 trial evaluating cholecalciferol (Vitamin D3) in adults with acute myeloid leukemia undergoing intensive induction chemotherapy; the…
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CLINICAL_TRIALS trial_result · 2015-06-19Clinical Trial Update: Maintenance Therapy in Acute Myeloid Leukemia (AML) Patients [Phase 2]
This document provides an update on a Phase 2 clinical trial evaluating maintenance therapy in patients with acute myeloid leukemia. The stu…
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CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: Abdominal CT to Predict the Risk of Acute Graft-versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation [EARLY_Phase 1]
An early-phase study update reporting completion of a trial using abdominal CT to predict acute graft-versus-host disease risk after allogen…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: 5-Fluoro-2'-Deoxycytidine and Tetrahydrouridine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes [Phase 1]
Phase 1 trial assessing 5-Fluoro-2'-Deoxycytidine with tetrahydrouridine in adults with acute myeloid leukemia or myelodysplastic syndromes;…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Phase I Study of OPB-51602 in Patients With Hematologic Malignancies [Phase 1]
Phase I trial results are reported for OPB-51602 in patients with hematologic malignancies including multiple myeloma, non-Hodgkin lymphoma,…
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CLINICAL_TRIALS trial_result · 2015-06-04Clinical Trial Update: HLA-mismatched MST vs HLA-matched NST for AML in Intermediate-risk [Phase 3]
This update notes the completion of a Phase 3 trial comparing HLA-mismatched hematopoietic stem cell transplantation to HLA-matched transpla…
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FDA approval · 2015-06-01FDA Approved: MITOXANTRONE — Supplemental Application (Fresenius Kabi USA, LLC)
FDA approved a supplemental application for mitoxantrone hydrochloride, submitted by Fresenius Kabi USA, LLC.
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CLINICAL_TRIALS research · 2015-05-27Clinical Trial Update: A Notch Signalling Pathway Inhibitor for Patients With T-cell Acute Lymphoblastic Leukemia/Lymphoma (ALL)(0752-013) [Phase 1]
Phase 1 trial of a Notch signaling pathway inhibitor (MK-0752) in T-cell acute lymphoblastic leukemia/lymphoma has been terminated.
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CLINICAL_TRIALS trial_result · 2015-05-25Clinical Trial Update: BI 811283 in Combination With Cytarabine in Previously Untreated AML Ineligible for Intensive Treatment [Phase 2]
Phase 2 trial update on BI 811283 in combination with cytarabine for adults with newly diagnosed acute myeloid leukemia ineligible for inten…
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CLINICAL_TRIALS trial_result · 2015-05-15Clinical Trial Update: T-Cell Depleted Double UCB for Refractory AML [Phase 2]
Phase 2 trial of T-cell depleted double umbilical cord blood for refractory acute myeloid leukemia has been terminated with posted results.
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: Chronic Graft-versus-host Disease (cGvHD) Prophylaxis With or Without ATG Prior to Stem Cell Transplantation (SCT) From HLA-identical Siblings in Patients With Acute Leukemia [Phase 3]
Phase 3 trial evaluating prophylaxis for chronic graft-versus-host disease using anti-thymocyte globulin (ATG) prior to stem cell transplant…
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CLINICAL_TRIALS trial_result · 2015-05-12Clinical Trial Update: Drug Biomarkers in Cell Samples From Patients With Acute Myeloid Leukemia
This completed clinical trial update reports analyses of drug biomarkers in cell samples from patients with acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2015-05-08Clinical Trial Update: Alloreactive NK Cells for Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) [Phase 1]
Phase 1 trial evaluating alloreactive NK cells as an adjunct to allogeneic stem cell transplantation in patients with myelodysplastic syndro…
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CLINICAL_TRIALS trial_result · 2015-05-08Clinical Trial Update: Phase 2 Study of Azacitidine (Vidaza) vs MGCD0103 vs Combination in Elderly Subjects With Newly Diagnosed Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) [Phase 2]
This Phase 2 trial comparing Vidaza (azacitidine), MGCD0103, and their combination in elderly patients with newly diagnosed acute myeloid le…
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias [Phase 1]
Phase 1 study of TH-302 (evofosfamide), a hypoxia-activated prodrug, in patients with advanced leukemias has been completed, with evaluation…
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: Biomarkers in Bone Marrow Samples From Patients With Acute Promyelocytic Leukemia
A completed clinical trial update reports biomarker analyses in bone marrow samples from patients with acute promyelocytic leukemia (APL). T…
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CLINICAL_TRIALS research · 2015-05-07Clinical Trial Update: Studying Biomarkers in Cell Samples From Patients With Acute Myeloid Leukemia
Completed study evaluating biomarkers in cell samples from patients with acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2015-05-06Clinical Trial Update: Biomarkers in Young Patients With Acute Myeloid Leukemia
A completed pediatric clinical trial from the Children's Oncology Group evaluated biomarkers in young patients with acute myeloid leukemia. …
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CLINICAL_TRIALS research · 2015-05-06Clinical Trial Update: Studying Gene Expression in Tissue Samples From Young Patients With Acute Myeloid Leukemia
The document reports on a completed study by the Children's Oncology Group investigating gene expression in tissue samples from young patien…