Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-23Clinical Trial Results: Fractionated Gemtuzumab Ozogamicin Followed by Non-engraftment Donor Leukocyte Infusions for Relapsed/Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating fractionated gemtuzumab ozogamicin followed by non-engraftment donor leukocyte infusions for relapsed/re…
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CLINICAL_TRIALS trial_result · 2026-07-14Clinical Trial Results: Blockade of PD-1 in Conjunction With the Dendritic Cell/AML Vaccine Following Chemotherapy Induced Remission [Phase 2]
Phase 2 trial evaluating PD-1 blockade with a dendritic cell/AML vaccine following chemotherapy-induced remission in acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2026-07-06Clinical Trial Results: First-in-human Study of SAR443579 Infusion in Male and Female Children and Adult Participants With Relapsed or Refractory Acute Myeloid Leukemia (R/R AML), B-cell Acute Lymphoblastic Leukemia (B-ALL), High Risk-myelodysplasia (HR-MDS), or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) [Phase 1, Phase 2]
First-in-human study results for SAR443579 in relapsed or refractory acute leukemias and BPDCN across Phase 1/2 cohorts; the study was termi…
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CLINICAL_TRIALS trial_result · 2026-06-29Clinical Trial Update: Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome [Phase 3]
Phase 3 trial comparing mismatched related donor versus matched unrelated donor stem cell transplantation in pediatric and young adult patie…
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CLINICAL_TRIALS trial_result · 2026-06-25Clinical Trial Update: Study to Compare Azacitidine Plus Pevonedistat Versus Azacitidine in Patients With Acute Myeloid Leukemia Not Eligible for Standard Chemotherapy [Phase 3]
Phase 3 trial comparing azacitidine plus pevonedistat versus azacitidine in adults with acute myeloid leukemia not eligible for standard che…
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CLINICAL_TRIALS trial_result · 2026-06-17Clinical Trial Results: A Study of E7820 in People With Bone Marrow (Myeloid) Cancers [Phase 2]
Phase 2 trial results for E7820 in myeloid bone marrow cancers have been completed with posted results.
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CLINICAL_TRIALS trial_result · 2026-06-11Clinical Trial Results: Venetoclax and Azacitidine for Non-Elderly Adult Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 trial results for venetoclax and azacitidine in non-elderly adults with acute myeloid leukemia (AML) completed.
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CLINICAL_TRIALS trial_result · 2026-06-08Clinical Trial Results: Recombinant EphB4-HSA Fusion Protein and Azacitidine or Decitabine for Relapsed or Refractory Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia Patients Previously Treated With a Hypomethylating Agent [Phase 2]
Phase 2 trial evaluating recombinant EphB4-HSA with azacitidine or decitabine in relapsed/refractory MDS, CMML, or AML after hypomethylating…
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CLINICAL_TRIALS trial_result · 2026-06-04Clinical Trial Results: A Study Evaluating Safety and Efficacy of Venetoclax in Combination With Azacitidine Versus Standard of Care After Allogeneic Stem Cell Transplantation (SCT) in Participants With Acute Myeloid Leukemia (AML) [Phase 3]
Phase 3 trial evaluating venetoclax plus azacitidine versus standard of care after allogeneic stem cell transplant in AML was terminated wit…
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML [Phase 2]
Phase 2 global trial evaluating midostaurin combined with chemotherapy in newly diagnosed pediatric patients with FLT3-mutated acute myeloid…
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: Decitabine, Cytarabine, and Daunorubicin Hydrochloride in Treating Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating the combination of decitabine, cytarabine, and daunorubicin hydrochloride for acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: Phase III Study Comparing GVHD Prophylaxis With ATG-thymoglobulin to ATLG-grafalon in Elderly Patients With Acute Myeloid Leukemia or Myelodysplasic Syndrome and Receiving an Allogeneic Hematopoietic Stem Cell Transplantation With a 10/10 HLA Matched Unrelated Donor [Phase 3]
Phase III study comparing ATG-thymoglobulin vs ATLG-grafalon for GVHD prophylaxis in elderly AML/MDS patients undergoing matched unrelated d…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Cytokine Induced Memory-like NK Cell Adoptive Therapy for Relapsed AML After Allogeneic Hematopoietic Cell Transplant [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating cytokine-induced memory-like natural killer (NK) cell adoptive therapy for relapsed acute myeloid leukem…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies [Phase 1]
Phase 1 clinical trial evaluating autologous T cells engineered with retroviral vectors to express TCRs against patient-specific neoantigens…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative Neoplasms [Phase 1, Phase 2]
The Phase 1/2 study evaluating the combination of ruxolitinib and CPX-351 in advanced phase myeloproliferative neoplasms was terminated, wit…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Magrolimab, Azacitidine, and Venetoclax for the Treatment of Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 trial of magrolimab in combination with azacitidine and venetoclax for acute myeloid leukemia has been terminated, with results po…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: A Study to Assess Safety, Tolerability and Preliminary Efficacy of Bexmarilimab in Combination With Standard of Care in Patients With Hematological Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Bexmarilimab in combination with standard of care for hematologic malignancies is active but not recru…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 2]
Phase 2 trial update on epigenetic priming in newly diagnosed acute myeloid leukemia; the study is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Pevonedistat and Decitabine in Treating Patients With High Risk Acute Myeloid Leukemia [Phase 1]
This update reports the completion of a Phase 1 study evaluating pevonedistat in combination with decitabine for high-risk acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Predictive Clinical and Biological Parameters in Acute Leukemia, Myelodysplastic Syndromes and Myeloproliferative Disorders-HEMATO-BIO-IPC-2013-015 [NA]
This clinical trial update reports on predictive clinical and biological parameters across acute leukemia, myelodysplastic syndromes, and my…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: A Phase II Study of Vibecotamab (XmAb14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure [Phase 2]
A Phase II clinical trial is evaluating Vibecotamab (XmAb14045) for patients with measurable residual disease-positive acute myeloid leukemi…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Validation Study of a New Cytokine-based Dynamic Stratification Based on FLt3 Ligand Plasma Concentration Kinetic Profile and IL-6 Concentration During Induction of Acute Myeloid Leukemia
This completed clinical trial validates a cytokine-based dynamic stratification approach using FLT3 ligand plasma concentration kinetics and…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Olutasidenib, Venetoclax, and Azacitidine in IDH1 Mutated Newly Diagnosed Acute Myeloid Leukemia Patients Eligible for Intensive Induction Chemotherapy [Phase 2]
A Phase 2 clinical trial is evaluating a triple combination of olutasidenib, venetoclax, and azacitidine in IDH1-mutated, newly diagnosed ac…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors [Phase 1, Phase 2]
The document reports ongoing Phase 1/2 clinical trials evaluating ponatinib in pediatric patients with recurrent or refractory leukemias, ly…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies [Phase 2]
Phase 2 study evaluating a two-step reduced-intensity conditioning approach for bone marrow transplant in adults with hematologic malignanci…