Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Hematopoietic Stem Cell Transplantation (HSCT) Using CD34 Selected Mismatched Related Donor and One Umbilical Cord Unit [Phase 2]
Phase 2 clinical trial evaluating hematopoietic stem cell transplantation using a CD34-selected mismatched related donor plus one umbilical …
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CLINICAL_TRIALS trial_result · 2015-09-22Clinical Trial Update: Azacitidine Compared to Conventional Chemotherapy as Consolidation of Elderly Patients With AML [Phase 2]
A Phase 2 trial comparing azacitidine versus conventional chemotherapy as consolidation therapy in elderly patients with acute myeloid leuke…
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CLINICAL_TRIALS research · 2015-09-21Clinical Trial Update: BL-8040 Addition to Consolidation Therapy in AML Patients [Phase 2]
This clinical trial update reports a Phase 2 study evaluating BL-8040 added to consolidation therapy in patients with Acute Myeloid Leukemia…
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CLINICAL_TRIALS trial_result · 2015-09-07Clinical Trial Update: Azacitidine and Lenalidomide for Acute Myeloid Leukemia [Phase 1, Phase 2]
The document reports completion and results posting for a Phase 1/2 trial of azacitidine plus lenalidomide in adults with acute myeloid leuk…
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CLINICAL_TRIALS withdrawal · 2015-08-31Clinical Trial Update: A Phase I Trial of Alloreactive Cell Infusion Following Transplantation of Haplotype Cells in Patients With Myeloid Malignancies [Phase 1]
A Phase I study of an alloreactive cell infusion following transplantation of haplotype cells in patients with myeloid malignancies has been…
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CLINICAL_TRIALS trial_result · 2015-08-20Clinical Trial Update: Azacitidine, Mitoxantrone Hydrochloride, and Etoposide in Treating Older Patients With Poor-Prognosis Acute Myeloid Leukemia [Phase 1]
A Phase 1 study evaluating a combination of azacitidine, mitoxantrone hydrochloride, and etoposide in older patients with poor-prognosis acu…
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CLINICAL_TRIALS trial_result · 2015-08-17Clinical Trial Update: Pilot Study Immunomonitoring Natural Killers Cells in Patients With Myeloid Malignancies Treated With Lenalidomide [NA]
A completed pilot clinical trial evaluated immunomonitoring of natural killer cells in patients with acute myeloid leukemia or myelodysplast…
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: Bortezomib, Mitoxantrone, Etoposide, and Cytarabine in Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
This entry reports the completion of a Phase 1 trial evaluating the combination of bortezomib, mitoxantrone, etoposide, and cytarabine in ad…
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: Decitabine (DAC) w/ or w/o Valproic Acid (VPA) in Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML) [Phase 2]
Phase 2 trial update of decitabine with or without valproic acid in myelodysplastic syndrome and acute myelogenous leukemia; completed with …
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CLINICAL_TRIALS trial_result · 2015-08-11Clinical Trial Update: Safety, Tolerability, Pharmacokinetics and Efficacy of AZD1208 in Acute Myelogenous Leukemia (AML) Patients [Phase 1]
Phase 1 clinical trial of AZD1208 in Acute Myeloid Leukemia assessed safety, tolerability, pharmacokinetics and preliminary efficacy; the st…
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CLINICAL_TRIALS trial_result · 2015-08-05Clinical Trial Update: Selumetinib in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial update evaluating selumetinib in adults with recurrent or refractory acute myeloid leukemia, including AML with t(15;…
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CLINICAL_TRIALS trial_result · 2015-07-28Clinical Trial Update: Phase 1 Study of CC-486 in Japanese Subjects With Hematological Neoplasms [Phase 1]
Termination of a Phase 1 trial evaluating oral azacitidine (CC-486) in Japanese subjects with hematological neoplasms.
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CLINICAL_TRIALS trial_result · 2015-07-27Clinical Trial Update: Combination of GTI-2040 and Cytarabine in the Treatment of Refractory and Relapsed Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 trial evaluating the combination of GTI-2040 and cytarabine in patients with refractory or relapsed acute myeloid leukemia. The stud…
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CLINICAL_TRIALS trial_result · 2015-07-23Clinical Trial Update: Lipid Use, Nutrition, and Colitis in Patients With Hematological Malignancies [Phase 2]
Phase 2 clinical trial assessing lipid use and nutrition for colitis and mucositis in patients with hematologic malignancies, including AML;…
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CLINICAL_TRIALS trial_result · 2015-07-23Clinical Trial Update: Tipifarnib, Cytarabine, and Daunorubicin in Treating Older Patients With Acute Myeloid Leukemia [Phase 1]
This Phase 1 trial studied a combination of tipifarnib, cytarabine, and daunorubicin in older patients with acute myeloid leukemia; the stud…
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CLINICAL_TRIALS trial_result · 2015-07-10Clinical Trial Update: Efficacy and Safety Study of StemEx®, to Treat Subjects With High Risk Hematologic Malignancies, Following Myeloablative Therapy [Phase 2, Phase 3]
This update summarizes a Phase 2/Phase 3 study of StemEx for high-risk hematologic malignancies after myeloablative therapy, focusing on eff…
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CLINICAL_TRIALS trial_result · 2015-07-07Clinical Trial Update: Comparing Three Different Combination Chemotherapy Regimens in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 trial results comparing three combination chemotherapy regimens in adults with relapsed or refractory acute myeloid leukemia; the st…
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CLINICAL_TRIALS research · 2015-07-07Clinical Trial Update: Phase I/II Trial of ATRA and TCP in Patients With Relapsed or Refractory AML and no Intensive Treatment is Possible [Phase 1, Phase 2]
This entry reports a Phase I/II clinical trial evaluating all-trans retinoic acid (ATRA) in combination with TCP in patients with relapsed o…
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CLINICAL_TRIALS trial_result · 2015-07-03Clinical Trial Update: Donor Natural Killer Cells and Aldesleukin in Treating Patients w/High Risk AML Undergoing Donor Stem Cell Transplant [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating donor natural killer cells plus aldesleukin in high-risk acute myeloid leukemia patients undergoing dono…
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CLINICAL_TRIALS research · 2015-07-03Clinical Trial Update: Evaluation of Cytidine Deaminase for Patient Suffering of a Myelodysplastic Syndrom or an AML Treated by Azacytidine [NA]
Clinical trial update exploring cytidine deaminase for patients with myelodysplastic syndromes or acute myeloid leukemia treated with azacit…
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CLINICAL_TRIALS trial_result · 2015-07-02Clinical Trial Update: Vorinostat in Combination With Azacitidine in Patients With Newly-Diagnosed Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 trial evaluating vorinostat in combination with azacitidine in newly diagnosed AML or MDS; study completed with results posted in 20…
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CLINICAL_TRIALS trial_result · 2015-07-01Clinical Trial Update: A Phase I/II Study of MGCD0103 With Azacitidine in Patients With High-Risk Myelodysplastic Syndrome (MDS) or Acute Myelogenous Leukemia [Phase 1, Phase 2]
A Phase I/II study evaluating the combination of MGCD0103 with azacitidine in high-risk myelodysplastic syndrome or acute myeloid leukemia h…
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CLINICAL_TRIALS trial_result · 2015-07-01Clinical Trial Update: MGCD0103 in Elderly Patients With Previously Untreated AML/High Risk MDS or Adults With Relapsed/Refractory Disease [Phase 2]
Phase 2 trial of MGCD0103 (mocetinostat) in elderly patients with previously untreated acute myeloid leukemia/high-risk myelodysplastic synd…
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CLINICAL_TRIALS trial_result · 2015-06-26Clinical Trial Update: Study of Infusion of Blood Cells (Lymphocytes) to Stimulate the Immune System to Fight Leukemia/Lymphoma [Phase 2]
A Phase 2 trial evaluating infusion of blood cells (lymphocytes) to stimulate the immune system for fighting leukemia/lymphoma was terminate…
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CLINICAL_TRIALS trial_result · 2015-06-24Clinical Trial Update: Disease Stabilization in AML by Treatment With ATRA, Valproic Acid and Low-dose Cytarabine [Phase 1, Phase 2]
A Phase 1/2 trial in Acute myeloid leukemia reports disease stabilization with a combination of all-trans retinoic acid, valproic acid, and …