Clinical Trial Update: Safety and Efficacy Study of Nilotinib Combined With Mitoxantrone, Etoposide, and High-dose Cytarabine Induction Chemotherapy Followed by Consolidation for Patients With C-kit Positive Acute Myeloid Leukemia [Phase 1, Phase 2]

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Summary

This terminated Phase 1/2 trial evaluated the safety and efficacy of adding nilotinib to a mitoxantrone, etoposide, and high-dose cytarabine induction regimen f…

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Diseases / indications

• Acute Myeloid Leukemia

Drugs mentioned

• CYTARABINE (CYTARABINE)
• Etoposide (Etoposide)
• Mitoxantrone (mitoxantrone)
• Nilotinib (nilotinib)

Snippet

Sponsor: University Health Network, Toronto | Conditions: Acute Myeloid Leukemia | Phase 1, Phase 2 | Status: TERMINATED