Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Lenalidomide in Acute Leukemias and Chronic Lymphocytic Leukemia. [Phase 1]
This update reports the completion of a Phase 1 trial evaluating lenalidomide in acute myeloid leukemia, acute lymphoblastic leukemia, and c…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Eltrombopag Treatment of Thrombocytopenia in Subjects With Advanced Myelodysplastic Syndrome (MDS) or Secondary Acute Myeloid Leukemia After MDS (sAML/MDS) [Phase 1]
A completed Phase 1 trial evaluating eltrombopag for treating thrombocytopenia in patients with advanced myelodysplastic syndromes or second…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Combination Study of GSK1120212 With Gemcitabine in Subjects With Solid Tumors [Phase 1]
Phase 1 trial evaluating the combination of trametinib (GSK1120212) and gemcitabine in subjects with solid tumors; the study has completed.
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FDA approval · 2017-11-09FDA Approved: CYTARABINE — Original Application (Meitheal Pharmaceuticals Inc.)
The FDA approved the original abbreviated new drug application for Cytarabine from Meitheal Pharmaceuticals, enabling the generic injectable…
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CLINICAL_TRIALS research · 2017-11-09Clinical Trial Update: Interest of a Therapeutic Follow-up of the Cytarabine in the Acute Myeloid Leukaemia: Is There Constitutional Biomarkers [NA]
This clinical trial update discusses the potential use of cytarabine in Acute Myeloid Leukemia and explores whether constitutional biomarker…
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CLINICAL_TRIALS trial_result · 2017-11-08Clinical Trial Update: T-cell Depleted Alternative Donor Transplantation [Phase 2]
Phase 2 clinical trial of T-cell depleted alternative donor transplantation for acute leukemias and related conditions was terminated with r…
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: Study Evaluating Orally Administered AMG 900 in Adult Subjects With Acute Myeloid Leukemia [Phase 1]
An early-phase trial evaluating orally administered AMG 900 in adults with acute myeloid leukemia has completed.
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FDA approval · 2017-11-03FDA Approved: DOXORUBICIN HYDROCHLORIDE — Supplemental Application (BluePoint Laboratories)
FDA approved a supplemental application for doxorubicin hydrochloride from BluePoint Laboratories, adding a new approved generic version of …
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CLINICAL_TRIALS trial_result · 2017-11-01Clinical Trial Update: Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients [Phase 2]
Phase 2 clinical trial of microtransplantation for refractory or relapsed hematologic malignancies in younger patients was terminated, with …
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CLINICAL_TRIALS withdrawal · 2017-10-19Clinical Trial Update: Donor Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia in Remission [Phase 2]
A Phase 2 trial evaluating donor stem cell transplant for adults with acute myeloid leukemia in remission has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-10-17Clinical Trial Update: CD123 Redirected Autologous T Cells for AML [EARLY_Phase 1]
An early-phase 1 trial assessing CD123-targeted autologous T cells for relapsed or refractory acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2017-10-02Clinical Trial Update: Phase III Study of CPX-351 Versus 7+3 in Patients 60-75 Years Old With Untreated High Risk (Secondary) Acute Myeloid Leukemia [Phase 3]
Phase III trial comparing CPX-351 to the 7+3 regimen in untreated high-risk secondary acute myeloid leukemia in patients aged 60-75 has comp…
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CLINICAL_TRIALS trial_result · 2017-09-29Clinical Trial Update: Trial of CPX-351 in Adult Patients With First Relapse Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 clinical trial results for CPX-351 in adults with first-relapse Acute Myeloid Leukemia have been completed, with results posted in 2…
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CLINICAL_TRIALS trial_result · 2017-09-27Clinical Trial Update: Study Evaluating the Safety and Efficacy of Astarabine in Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
A completed phase 1/2 trial evaluating safety and efficacy of Astarabine in acute myeloid leukemia and acute lymphoblastic leukemia.
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FDA approval · 2017-09-22FDA Approved: DECITABINE — Original Application (Amneal Pharmaceuticals LLC)
FDA approved Amneal's original ANDA for decitabine, a generic chemotherapy agent. It is indicated for the treatment of myelodysplastic syndr…
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CLINICAL_TRIALS trial_result · 2017-09-20Clinical Trial Update: Study on All-Trans Retinoic Acid, Induction and Consolidation Therapy, and Pegfilgrastim After Consolidation Therapy in Younger Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 2, Phase 3]
Phase 2/3 trial evaluating all-trans retinoic acid with induction and consolidation therapy plus pegfilgrastim in younger patients with newl…
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CLINICAL_TRIALS trial_result · 2017-09-20Clinical Trial Update: Study of Vosaroxin and Cytarabine for the Treatment of Adults 60 Years of Age or Older With Previously Untreated AML [NA]
A terminated clinical trial in older adults with previously untreated acute myeloid leukemia evaluating vosaroxin and cytarabine; results po…
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CLINICAL_TRIALS trial_result · 2017-09-15Clinical Trial Update: Pilot of Abatacept-based Immunosuppression for Prevention of Acute GvHD During Unrelated Donor HCT [Phase 2]
Phase 2 trial evaluating abatacept-based immunosuppression to prevent acute graft-versus-host disease during unrelated donor hematopoietic c…
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CLINICAL_TRIALS trial_result · 2017-09-14Clinical Trial Update: Phase II Study of Decitabine and Cytarabine for Older Patients With Newly Diagnosed Acute Myeloid Leukemia (AML) [Phase 2]
Phase II study evaluating decitabine and cytarabine in older patients with newly diagnosed acute myeloid leukemia; the trial is completed wi…
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CLINICAL_TRIALS trial_result · 2017-09-08Clinical Trial Update: Clofarabine, Cytarabine, and G-CSF in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of clofarabine, cytarabine, and G-CSF in relapsed or refractory acute myeloid leukemia…
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FDA approval · 2017-09-01FDA Approved: MYLOTARG — Original Application (Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.)
FDA approval of Mylotarg (gemtuzumab ozogamicin) under the original application from Wyeth/Pfizer for treatment of acute myeloid leukemia.
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CLINICAL_TRIALS withdrawal · 2017-08-31Clinical Trial Update: iCare3: Monitoring Circulating Cancer DNA After Chemotherapy in MDS and AML
A clinical trial (NCT03138395) investigating monitoring circulating cancer DNA after chemotherapy in Acute myeloid leukemia and Myelodysplas…
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CLINICAL_TRIALS trial_result · 2017-08-30Clinical Trial Update: Radiolabeled BC8 Antibody, Busulfan, Cyclophosphamide Followed by Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia in First Remission [Phase 2]
Phase 2 trial evaluating radiolabeled BC8 antibody with busulfan and cyclophosphamide followed by donor stem cell transplant in adults with …
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CLINICAL_TRIALS trial_result · 2017-08-30Clinical Trial Update: Donor Peripheral Blood Stem Cell Transplant and Pretargeted Radioimmunotherapy in Treating Patients With High-Risk Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome [Phase 1]
Phase 1 trial evaluating donor peripheral blood stem cell transplantation in combination with pretargeted radioimmunotherapy for patients wi…
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CLINICAL_TRIALS trial_result · 2017-08-30Clinical Trial Update: Mismatched Donor Cells to Treat Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial is evaluating mismatched donor cells to treat Acute Myeloid Leukemia. The study status is currently UNKNOWN.