Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-01-02Clinical Trial Update: Cyclophosphamide and Busulfan Followed by Donor Stem Cell Transplant in Treating Patients With Myelofibrosis, Acute Myeloid Leukemia, or Myelodysplastic Syndrome [NA]
Clinical trial update on cyclophosphamide and busulfan followed by donor stem cell transplant for myelofibrosis, AML, or myelodysplastic syn…
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CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: A Study of RO6870810/TEN-010 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndrome [Phase 1]
Phase 1 study of RO6870810/TEN-010 in patients with Acute Myeloid Leukemia and Myelodysplastic Syndromes has completed.
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CLINICAL_TRIALS research · 2017-12-08Clinical Trial Update: Hematopoietic Stem Cell Microtransplantation for in AML [NA]
This entry reports on a clinical trial evaluating hematopoietic stem cell microtransplantation for acute myeloid leukemia. The study status …
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CLINICAL_TRIALS trial_result · 2017-12-08Clinical Trial Update: Decitabine and Selinexor in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
This Phase 1 trial updates the safety and preliminary activity of decitabine combined with selinexor in patients with relapsed or refractory…
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CLINICAL_TRIALS trial_result · 2017-12-08Clinical Trial Update: Rasburicase and Allopurinol in Treating Patients With Hematologic Malignancies [Phase 2]
Phase 2 trial evaluating rasburicase and allopurinol in adults with hematologic malignancies; the study was terminated with results posted i…
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CLINICAL_TRIALS trial_result · 2017-12-06Clinical Trial Update: Evaluation of "Dose-dense Therapy" by S-HAM in Comparison to Conventionally Timed Double Induction in Patients With Acute Myeloid Leukemia (AML) [Phase 3]
A Phase 3 trial comparing dose-dense S-HAM therapy to conventionally timed double induction in acute myeloid leukemia has completed. The upd…
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CLINICAL_TRIALS research · 2017-12-06Clinical Trial Update: Antiminor Histocompatibility Complex (MiHA) T Cells for Patients With Relapsed Hematologic Malignancies Following Matched HSCT (Guided Lymphocyte Immunopeptide Derived Expansion) [Phase 1, Phase 2]
Phase 1/2 study investigating Antiminor Histocompatibility Complex (MiHA) T cells in patients with relapsed hematologic malignancies after m…
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CLINICAL_TRIALS trial_result · 2017-12-06Clinical Trial Update: MEK Inhibitor MEK162, Idarubicin, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 trial evaluating a MEK inhibitor (MEK162) in combination with idarubicin and cytarabine for adults with relapsed or refractory acu…
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CLINICAL_TRIALS withdrawal · 2017-12-05Clinical Trial Update: StemRegenin-1 Expanded vs Unexpanded UCB for High Risk Heme Malignancies [Phase 2]
Phase 2 trial evaluating StemRegenin-1-expanded versus unexpanded umbilical cord blood for high-risk hematologic malignancies has been withd…
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CLINICAL_TRIALS trial_result · 2017-12-05Clinical Trial Update: AHN-12 Biodistribution in Advanced Leukemia [Phase 1]
A Phase 1 trial of the investigational agent AHN-12 focusing on biodistribution in advanced leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2017-12-04Clinical Trial Update: Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant [Phase 3]
Phase 3 trial update on graft-versus-host disease prophylaxis in patients with hematologic malignancies undergoing unrelated donor periphera…
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CLINICAL_TRIALS trial_result · 2017-12-04Clinical Trial Update: Evaluating Cell Damage in Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, or Fanconi Anemia; in Patients Who Were Exposed to Alkylating Agents; and in Healthy Volunteers
A completed clinical trial evaluating cell damage from alkylating agents in patients with acute myeloid leukemia, myelodysplastic syndromes,…
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CLINICAL_TRIALS withdrawal · 2017-12-02Clinical Trial Update: T-Regulatory Cell and CD3 Depleted Double Umbilical Cord Blood Transplantation in Hematologic Malignancies [Phase 1, Phase 2]
A trial investigating T-regulatory cell and CD3-depleted double umbilical cord blood transplantation for hematologic malignancies has been w…
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CLINICAL_TRIALS withdrawal · 2017-12-02Clinical Trial Update: CD3/CD19 Depleted or CD3 Depleted/CD56 Selected Haploid Donor Natural Killer Cell Treatment in Older AML in First Complete Remission [Phase 2]
A Phase 2 trial evaluating haploidentical donor natural killer cell therapy using CD3/CD19-depleted or CD3-depleted/CD56-selected NK cells f…
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CLINICAL_TRIALS withdrawal · 2017-12-02Clinical Trial Update: Clofarabine, Cyclophosphamide and Etoposide for Minimal Residual Disease Positive Acute Leukemia [Phase 2]
Phase 2 trial evaluating clofarabine, cyclophosphamide, and etoposide for minimal residual disease-positive acute leukemia has been withdraw…
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CLINICAL_TRIALS trial_result · 2017-11-30Clinical Trial Update: An Open Label Phase II Pharmacokinetic and Pharmacodynamic Assessment of the Potential for QTc Prolongation Following First Induction Treatment With CPX-351 (Cytarabine:Daunorubicin) Liposome Injection in Acute Leukemias and MDS Patients [Phase 2]
This Phase 2 open-label pharmacokinetic/pharmacodynamic trial evaluated CPX-351 (cytarabine:daunorubicin liposome injection) for potential Q…
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Maintenance Therapy With Ceplene® (Histamine) and IL-2 on Immune Response and MRD in Acute Myeloid Leukemia [Phase 4]
Phase 4 clinical trial evaluating maintenance therapy with Ceplene (histamine dihydrochloride) and interleukin-2 in acute myeloid leukemia t…
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CLINICAL_TRIALS research · 2017-11-29Clinical Trial Update: DLAAG in the Treatment of Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome With Blast Excess [Phase 2]
A Phase 2 clinical trial evaluating DLAAG for acute myeloid leukemia and myelodysplastic syndrome with blast excess, with status currently u…
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Donor Lymphocyte Infusion (DLI) for Relapsed (Post Transplant) Leukemia [NA]
The document reports the completion of a clinical trial evaluating donor lymphocyte infusion for relapsed leukemia after transplantation acr…
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CLINICAL_TRIALS trial_result · 2017-11-22Clinical Trial Update: Treatment With Low-Dose Cytarabine in Elderly Patients (Age 70 Years or Older) With Acute Myeloid Leukemia: A Single Institution Experience.
This clinical trial update summarizes results from a single-institution experience using low-dose cytarabine in elderly patients (70 years o…
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: ABT-348 as Monotherapy and in Combination With Azacitidine to Treat Advanced Hematologic Malignancies [Phase 1]
A Phase 1 trial evaluated ABT-348 as a standalone therapy and in combination with azacitidine for advanced hematologic malignancies; the stu…
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CLINICAL_TRIALS research · 2017-11-20Clinical Trial Update: Observational Study of Patients Older Than 60 Years With Acute Myeloblastic Leukemia
This is an observational study focusing on patients older than 60 with acute myeloid leukemia. The current study status is UNKNOWN.
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Idarubicin, Cytarabine, and Pravastatin Sodium in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes [NA]
This clinical trial evaluated a combination of idarubicin, cytarabine, and pravastatin sodium in adults with acute myeloid leukemia or myelo…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Gluten Free Diet in Diminishing Side Effects Patients With Acute Myeloid Leukemia Undergoing Induction Chemotherapy [Phase 2]
A Phase 2 clinical trial testing whether a gluten-free diet reduces side effects in patients with acute myeloid leukemia undergoing inductio…
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CLINICAL_TRIALS research · 2017-11-17Clinical Trial Update: AML Treatment in Untreated Adult Patients [NA]
An update on a clinical trial evaluating treatment for untreated adult patients with acute myeloid leukemia is provided. The update does not…