Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-08-29Clinical Trial Update: Haploidentical NK-cell Infusion in Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 trial of haploidentical NK-cell infusion in Acute Myeloid Leukemia has completed.
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CLINICAL_TRIALS approval · 2017-08-22Clinical Trial Update: EAP of CPX-351 (VYXEOS) for Patients 60-75 Years of Age With Secondary AML
CPX-351 (Vyxeos) has received marketing approval for adults aged 60-75 with secondary acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Azacytidine and Bortezomib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes [Phase 1]
Phase 1 study of azacitidine plus bortezomib in relapsed or refractory acute myeloid leukemia or myelodysplastic syndromes has completed enr…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: PK Study of Oral and IV Clofarabine in High Risk Myelodysplasia+Acute Leukemias [Phase 1]
Phase 1 pharmacokinetic study of oral and intravenous clofarabine in high-risk myelodysplastic syndrome and acute leukemias; the trial has c…
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CLINICAL_TRIALS research · 2017-08-21Clinical Trial Update: Low Dose Decitabine + Modified BUCY Conditioning Regimen for High Risk Acute Myeloid Leukemia Undergoing Allo-HSCT [Phase 2, Phase 3]
Clinical trial update describing the use of low-dose decitabine with a modified BUCY conditioning regimen for high-risk acute myeloid leukem…
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CLINICAL_TRIALS trial_result · 2017-08-18Clinical Trial Update: Bendamustine and Idarubicin in Treating Older Patients With Previously Untreated AML or MDS [Phase 1, Phase 2]
This clinical trial update describes the Phase 1/2 results for the combination of bendamustine and idarubicin in older patients with previou…
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CLINICAL_TRIALS trial_result · 2017-08-18Clinical Trial Update: Lenalidomide in Combination With Microtransplantation as Post-remission Therapy in AML [Phase 1]
A Phase 1 trial evaluating lenalidomide in combination with microtransplantation as post-remission therapy for acute myeloid leukemia has be…
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CLINICAL_TRIALS trial_result · 2017-08-17Clinical Trial Update: Safety and Efficacy Study of PRI-724 in Subjects With Advanced Myeloid Malignancies [Phase 1, Phase 2]
A completed Phase 1/2 study of PRI-724 in adults with advanced myeloid malignancies (acute and chronic myeloid leukemia) evaluated safety an…
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CLINICAL_TRIALS trial_result · 2017-08-17Clinical Trial Update: Physical Activity in Older Patients With Acute Myeloid Leukemia Undergoing Chemotherapy [NA]
This clinical trial update notes the completion of a study examining the effects of physical activity in older adults with acute myeloid leu…
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EMA withdrawal · 2017-08-15EMA Application withdrawn: Qinprezo (vosaroxin) — Sunesis Europe Ltd
European EMA withdrawn the application for Qinprezo (vosaroxin) for acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2017-08-11Clinical Trial Update: Targeted, Dose-Escalation Busulfan-Etoposide as Prep Regimen [Phase 1]
Phase 1 trial evaluating a targeted, dose-escalation busulfan-etoposide conditioning regimen for acute myeloid leukemia. The study status is…
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CLINICAL_TRIALS research · 2017-08-10Clinical Trial Update: Analysis of Genetic Factors Related to Predisposition and Prognosis of Hematological Malignancies in Israel
A completed Israeli clinical trial analyzing genetic factors associated with predisposition and prognosis of hematologic malignancies, inclu…
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CLINICAL_TRIALS trial_result · 2017-08-09Clinical Trial Update: Randomized HaploCord Blood Transplantation vs. Double Umbilical Cord Blood Transplantation for Hematologic Malignancies [Phase 2]
This Phase 2 randomized trial comparing haplo cord blood transplantation versus double umbilical cord blood transplantation for hematologic …
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CLINICAL_TRIALS trial_result · 2017-08-08Clinical Trial Update: A Phase I Clinical Trial of OXi4503 for Relapsed and Refractory AML and MDS [Phase 1]
Phase I trial of OXi4503 for relapsed and refractory acute myeloid leukemia and myelodysplastic syndromes was terminated.
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: Decitabine, Vorinostat, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1]
This Phase 1 trial evaluated the safety and preliminary activity of a three-drug combination—decitabine, vorinostat, and cytarabine—in patie…
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FDA approval · 2017-08-01FDA Approved: IDHIFA — Original Application (Celgene Corporation)
FDA approves IDHIFA (enasidenib) in the original application for adult patients with relapsed or refractory acute myeloid leukemia harboring…
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FDA approval · 2017-07-28FDA Approved: AZACITIDINE — Supplemental Application (Dr. Reddy's Laboratories Inc.)
FDA approved Dr. Reddy's Laboratories Inc.'s supplemental application for azacitidine. The action pertains to a supplemental filing for the …
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CLINICAL_TRIALS trial_result · 2017-07-28Clinical Trial Update: Efficacy and Safety Study of Recombinant Human Arginase 1 in Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial update on the efficacy and safety of recombinant human arginase 1 in relapsed or refractory acute myeloid leukemia; c…
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: A Study to Determine Final Geriatric Assessment in Haematology (GAH) Score as a Tool for Predicting Tolerance to Treatment in Elderly Patients (≥ 65 Years) With Haematologic Neoplasms
Completed clinical trial evaluating whether the final Geriatric Assessment in Haematology (GAH) score can predict tolerance to treatment in …
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CLINICAL_TRIALS trial_result · 2017-07-24Clinical Trial Update: Posaconazole Versus Micafungin for Prophylaxis Against Invasive Fungal Infections During Neutropenia in Patients Undergoing Chemotherapy for Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia or Myelodysplastic Syndrome [Phase 4]
This Phase 4 trial compares posaconazole to micafungin for preventing invasive fungal infections during neutropenia in patients receiving ch…
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: Phase I Trial of Cabozantinib in Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
Phase I trial of cabozantinib in patients with relapsed or refractory acute myeloid leukemia has been completed.
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CLINICAL_TRIALS trial_result · 2017-07-19Clinical Trial Update: Allogeneic Stem Cell Transplant With Clofarabine, Busulfan and Antithymocyte Globulin (ATG) for Adult Patients With High-risk Acute Myeloid Leukemia/Myelodysplastic Syndromes (AML/MDS) or Acute Lymphoblastic Leukemia (ALL) [Phase 2]
Phase 2 trial evaluating an allogeneic stem cell transplant regimen combining clofarabine, busulfan, and antithymocyte globulin in adults wi…
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CLINICAL_TRIALS research · 2017-07-19Clinical Trial Update: Changes in the Gut Microbiota of Patients Undergoing Allogeneic Stem Cell Transplantation (COLLECT)
This clinical trial update describes observed changes in the gut microbiota of patients undergoing allogeneic hematopoietic stem cell transp…
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CLINICAL_TRIALS trial_result · 2017-07-17Clinical Trial Update: Preservation of Ovarian Function After Hematopoietic Cell Transplant [Phase 2]
Phase 2 trial investigating preservation of ovarian function after hematopoietic cell transplantation in patients with hematologic cancers; …
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CLINICAL_TRIALS trial_result · 2017-07-17Clinical Trial Update: PKC412 in Participants With Acute Myeloid Leukemia or With Myelodysplastic Syndrome (CPKC412A2104 Core); and PKC412 in Participants With Acute Myeloid Leukemia or With Myelodysplastic Syndrome With Either Wild Type or Mutated FMS-like Tyrosine Kinase 3 (FLT3) (CPKC412A2104E1 and CPKC412A2104E2) [Phase 1, Phase 2]
This clinical trial update reports the completion and posted results of Phase 1 and Phase 2 studies of PKC412 (midostaurin) in adults with a…