Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2018-03-30Clinical Trial Update: Phase II Study of 5-azacytidine Maintenance After Transplant for AML or MDS [Phase 2]
A Phase II study evaluating maintenance therapy with 5-azacitidine after stem cell transplant in acute myeloid leukemia or myelodysplastic s…
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CLINICAL_TRIALS trial_result · 2018-03-30Clinical Trial Update: Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia [Phase 1]
A Phase 1 study examining donor stem cell transplant for high-risk acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2018-03-21Clinical Trial Update: Ipilimumab in Treating Patients With Relapsed or Refractory High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia [Phase 1]
A Phase 1 study evaluating ipilimumab in patients with relapsed or refractory high-risk myelodysplastic syndrome or acute myeloid leukemia h…
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CLINICAL_TRIALS research · 2018-03-20Clinical Trial Update: Phase I/II Study With Oral Panobinostat Maintenance Therapy Following Allogeneic Stem Cell Transplantation in Patients With High Risk Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
This is a Phase I/II clinical trial evaluating oral panobinostat as maintenance therapy after allogeneic stem cell transplantation in patien…
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CLINICAL_TRIALS trial_result · 2018-03-19Clinical Trial Update: Mitomycin and Mitoxantrone in Treating Patients With Acute Myelogenous Leukemia [Phase 1]
Phase 1 clinical trial update evaluating mitomycin C and mitoxantrone in patients with acute myeloid leukemia has completed.
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CLINICAL_TRIALS withdrawal · 2018-03-14Clinical Trial Update: Pharmacokinetic and Pharmacodynamic Assessment of Treatment With CPX-351 (Cytarabine: Daunorubicin) Liposome for Injection in Acute Leukemias and MDS Patients With Moderate Hepatic Impairment [Phase 2]
Clinical trial update notes that a Phase 2 study evaluating the pharmacokinetics and pharmacodynamics of CPX-351 in acute leukemias and myel…
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CLINICAL_TRIALS trial_result · 2018-03-12Clinical Trial Update: 1336GCC: Study of Erwinaze for Treatment of Acute Myeloid Leukemia (AML) [Phase 1]
This update notes the completion of a Phase 1 clinical trial evaluating Erwinaze for Acute Myeloid Leukemia.
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CLINICAL_TRIALS trial_result · 2018-03-09Clinical Trial Update: Vaccine Therapy and Basiliximab in Treating Patients With Acute Myeloid Leukemia in Complete Remission [Phase 1]
Phase 1 trial update evaluating a cancer vaccine therapy in combination with Basiliximab for adults with acute myeloid leukemia (in remissio…
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CLINICAL_TRIALS withdrawal · 2018-03-06Clinical Trial Update: Minnelide in Adult Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
The Phase 1 trial of Minnelide in adults with relapsed or refractory acute myeloid leukemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-03-05Clinical Trial Update: DCHA as Postremission Therapy for AML With t(8;21) [Phase 1, Phase 2]
A clinical trial update describing Phase 1 and Phase 2 studies of DCHA as postremission therapy for acute myeloid leukemia with t(8;21).
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CLINICAL_TRIALS approval · 2018-03-02Clinical Trial Update: Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Acute Promyelocytic Leukemia
Gemtuzumab ozogamicin has been approved for marketing for relapsed or refractory acute myeloid leukemia and acute promyelocytic leukemia bas…
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CLINICAL_TRIALS trial_result · 2018-02-28Clinical Trial Update: Trial of Intensive Chemotherapy With or Without Volasertib in Patients With Newly Diagnosed High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) [Phase 2]
A Phase 2 trial of intensive chemotherapy with or without volasertib in newly diagnosed high-risk myelodysplastic syndrome and acute myeloid…
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CLINICAL_TRIALS trial_result · 2018-02-14Clinical Trial Update: Chidamide Plus DCAG for Relapsed/Refractory AML [Phase 1, Phase 2]
Phase 1/2 trial investigating chidamide in combination with DCAG for relapsed or refractory acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2018-02-01Clinical Trial Update: Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic Malignancies [Phase 2]
Phase 2 trial of bortezomib plus vorinostat in younger patients with MLL-rearranged hematologic malignancies was terminated; results were po…
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CLINICAL_TRIALS trial_result · 2018-01-23Clinical Trial Update: A Phase 2 Study of ABT-199 in Subjects With Acute Myelogenous Leukemia (AML) [Phase 2]
A Phase 2 trial of venetoclax (ABT-199) in patients with acute myeloid leukemia has completed enrollment with results posted.
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CLINICAL_TRIALS trial_result · 2018-01-23Clinical Trial Update: Safety & Efficacy of Atorvastatin for Prophylaxis of Acute Graft Versus Host Disease in Patients With Hematological Malignancies HLA- Donor Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 trial evaluating atorvastatin for prophylaxis of acute graft-versus-host disease in patients undergoing HLA-mon donor hematopoietic …
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CLINICAL_TRIALS trial_result · 2018-01-16Clinical Trial Update: Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT [Phase 2]
Phase 2 trial evaluating post-transplant cyclophosphamide as graft-versus-host disease prophylaxis after allogeneic hematopoietic stem cell …
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CLINICAL_TRIALS trial_result · 2018-01-12Clinical Trial Update: Trial of CPX-351 in Newly Diagnosed Elderly AML Patients [Phase 2]
Phase 2 trial update of CPX-351 in newly diagnosed elderly patients with acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2018-01-12Clinical Trial Update: Decitabine Followed by Mitoxantrone Hydrochloride, Etoposide, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating decitabine followed by mitoxantrone, etoposide, and cytarabine in adults with relapsed/refractory acute …
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FDA approval · 2018-01-10FDA Approved: AZACITIDINE — Supplemental Application (BluePoint Laboratories)
The FDA approved a supplemental application for azacitidine submitted by BluePoint Laboratories. This indicates regulatory approval of modif…
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CLINICAL_TRIALS trial_result · 2018-01-10Clinical Trial Update: MT2014-25: Haplo NK With SQ IL-15 in Adult Relapsed or Refractory AML Patients [Phase 2]
Phase 2 trial of haploidentical NK cells with SQ IL-15 in adults with relapsed or refractory acute myeloid leukemia has completed with poste…
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CLINICAL_TRIALS trial_result · 2018-01-09Clinical Trial Update: Safety and Tolerability Study of Voreloxin and Cytarabine Combination in Acute Myeloid Leukemia in Humans [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating the safety and tolerability of the combination of voreloxin and cytarabine in adults with acute myeloi…
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CLINICAL_TRIALS trial_result · 2018-01-05Clinical Trial Update: Dose Escalation Phase I/II Study of Lovastatin With High-Dose Cytarabine for Refractory or Relapsed AML [Phase 1, Phase 2]
Phase I/II dose-escalation trial evaluating lovastatin with high-dose cytarabine for refractory or relapsed acute myeloid leukemia; study TE…
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CLINICAL_TRIALS trial_result · 2018-01-04Clinical Trial Update: Decitabine,Cytarabine and Arsenic Trioxide for Acute Myeloid Leukemia With p53 Mutations [Phase 2]
Phase 2 clinical trial update investigating a regimen of decitabine, cytarabine, and arsenic trioxide for acute myeloid leukemia with p53 mu…
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CLINICAL_TRIALS trial_result · 2018-01-03Clinical Trial Update: Azacitidine + Lenalidomide Combo in the Elderly With Previously Treated AML & High-Risk MDS [Phase 2]
Phase 2 trial update of azacitidine plus lenalidomide in elderly patients with previously treated acute myeloid leukemia and high-risk myelo…