Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-05-30Clinical Trial Update: Reduced Intensity Regimen vs Myeloablative Regimen for Myeloid Leukemia or Myelodysplastic Syndrome (BMT CTN 0901) [Phase 3]
Phase 3 trial comparing reduced intensity conditioning to myeloablative conditioning for acute myeloid leukemia and myelodysplastic syndrome…
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CLINICAL_TRIALS trial_result · 2018-05-25Clinical Trial Update: Liposomal Cytarabine-Daunorubicin CPX-351 in Treating Patients With Untreated Myelodysplastic Syndrome or Acute Myeloid Leukemia [NA]
ClinicalTrials.gov update on a completed trial evaluating CPX-351 (liposomal cytarabine-daunorubicin) for untreated myelodysplastic syndrome…
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CLINICAL_TRIALS trial_result · 2018-05-23Clinical Trial Update: A Study To Evaluate PF-04449913 With Chemotherapy In Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 2]
Phase 2 trial updating the evaluation of PF-04449913 in combination with chemotherapy for acute myeloid leukemia, with completed status and …
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CLINICAL_TRIALS trial_result · 2018-05-21Clinical Trial Update: Treo/Flu/TBI With Donor Stem Cell Transplant for Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating Treo/Flu/TBI with donor stem cell transplant for myelodysplastic syndrome or acute myeloid leukemia.
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CLINICAL_TRIALS withdrawal · 2018-05-21Clinical Trial Update: Arsenic Trioxide in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
A Phase 2 trial of arsenic trioxide for relapsed or refractory acute myeloid leukemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-05-17Clinical Trial Update: A Study of the Safety and Pharmacokinetics of RO6839921, An MDM2 Antagonist, in Patients With Advanced Cancers, Including Acute Myeloid Leukemia. [Phase 1]
Phase 1 study assessing safety and pharmacokinetics of RO6839921 (idasanutlin), an MDM2 antagonist, in patients with advanced cancers includ…
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CLINICAL_TRIALS trial_result · 2018-05-14Clinical Trial Update: Ibrutinib, Idarubicin and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 trial evaluating a combination of ibrutinib, idarubicin, and cytarabine in adults with relapsed or refractory acute myeloid leukemia…
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CLINICAL_TRIALS other · 2018-05-14Clinical Trial Update: A Safety Study of SGN-CD123A in Patients With Acute Myeloid Leukemia [Phase 1]
Phase 1 safety study of SGN-CD123A in patients with Acute Myeloid Leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: A Phase 2 Trial of MLN8237 in Adult Participants With Acute Myelogenous Leukemia and High-Grade Myelodysplastic Syndrome [Phase 2]
A Phase 2 clinical trial update on MLN8237 (alisertib) in adults with acute myeloid leukemia and high-grade myelodysplastic syndrome; the st…
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CLINICAL_TRIALS trial_result · 2018-05-09Clinical Trial Update: A Safety Study of SGN-CD33A in Combination With Standard-of-care in Patients With AML [Phase 1]
A completed Phase 1 safety study evaluating SGN-CD33A in combination with standard-of-care in patients with acute myeloid leukemia.
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CLINICAL_TRIALS withdrawal · 2018-05-04Clinical Trial Update: Midostaurin in Treating Older Patients With Mutated Acute Myeloid Leukemia Post-Transplant [Phase 2]
A Phase 2 study of midostaurin in older patients with AML with gene mutations after transplant has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-05-04Clinical Trial Update: Volasertib Combined With Induction Chemotherapy in Acute Myeloid Leukemia [Phase 1]
A phase 1 trial evaluating volasertib in combination with induction chemotherapy for acute myeloid leukemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-04-27Clinical Trial Update: Pilot Study Efficacy and Tolerance Fish Oil Emulsion Daunorubicin and Cytarabine Treatment of AML Younger Patients [Phase 2]
Phase 2 pilot study assessing efficacy and tolerability of a fish oil emulsion combined with daunorubicin and cytarabine in younger patients…
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: Respiratory Viral Infections During Acute Myeloid Leukemia (AML)Chemotherapy Related Aplasia [Phase 4]
A Phase 4 clinical trial evaluating respiratory viral infections during chemotherapy-induced aplasia in patients with acute myeloid leukemia…
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CLINICAL_TRIALS research · 2018-04-20Clinical Trial Update: Screening of IDH1 and IDH2 Gene Mutations in Adult Acute Myeloid Leukemia for Possible Targeted Therapy
This Clinical Trial Update reports on screening adult AML patients for IDH1 and IDH2 mutations to identify candidates for targeted therapy.
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CLINICAL_TRIALS withdrawal · 2018-04-19Clinical Trial Update: Dasatinib in Combination With Chemotherapy for Relapsed or Refractory Core Binding Factor Acute Myeloid Leukemia [Phase 1]
A Phase 1 study of dasatinib in combination with chemotherapy for relapsed or refractory core-binding factor acute myeloid leukemia has been…
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CLINICAL_TRIALS trial_result · 2018-04-18Clinical Trial Update: Oshadi D & Oshadi R Combined With Salvage Chemotherapy for Relapsed Acute Myeloid Leukemia or Lymphoid Leukemia Patients [Phase 2]
Phase 2 trial evaluating Oshadi D and Oshadi R combined with salvage chemotherapy in relapsed acute myeloid leukemia and lymphoid leukemia i…
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CLINICAL_TRIALS trial_result · 2018-04-13Clinical Trial Update: Decitabine and Cytarabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia, High Risk Myelodysplastic Syndrome, or Myeloproliferative Neoplasm [NA]
This clinical trial update reports results for using decitabine plus cytarabine in older adults with untreated acute myeloid leukemia, high-…
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CLINICAL_TRIALS trial_result · 2018-04-10Clinical Trial Update: Phase 2 Haplotype Mismatched HSCT in Patients With Hematological Malignancies [Phase 2]
A Phase 2 trial evaluated haplotype-mismatched hematopoietic stem cell transplantation in patients with hematological malignancies. The stud…
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FDA approval · 2018-04-09FDA Approved: MYLOTARG — Supplemental Application (Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.)
The FDA approved a supplemental application for MYLOTARG (gemtuzumab ozogamicin) submitted by Wyeth Pharmaceuticals LLC (a subsidiary of Pfi…
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CLINICAL_TRIALS research · 2018-04-09Clinical Trial Update: Maintenance Therapy With Histamine Dihydrochloride and Interleukin-2 in Adult Acute Myeloid Leukemia (AML) Patients With Measurable Minimal Residual Disease (MRD)- a Non-interventional Study (NIS)
The document reports a terminated non-interventional study evaluating maintenance therapy with histamine dihydrochloride and interleukin-2 i…
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CLINICAL_TRIALS trial_result · 2018-04-06Clinical Trial Update: Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating trametinib in combination with the AKT inhibitor GSK2141795 for acute myeloid leukemia was terminated, with results…
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CLINICAL_TRIALS trial_result · 2018-04-06Clinical Trial Update: Treatment of Elderly AML Patients With Induction Chemotherapy Followed by G-CSF-Mobilized Stem Cells From Haploidentical Related Donors [NA]
Terminated clinical trial evaluating induction chemotherapy in elderly acute myeloid leukemia patients followed by G-CSF-mobilized haploiden…
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CLINICAL_TRIALS trial_result · 2018-04-03Clinical Trial Update: Busulfan, Fludarabine Phosphate, and Anti-Thymocyte Globulin Followed By Donor Stem Cell Transplant and Azacitidine in Treating Patients With High-Risk Myelodysplastic Syndrome and Older Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating a conditioning regimen of busulfan, fludarabine phosphate, and anti-thymocyte globulin followed by donor stem cell …
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CLINICAL_TRIALS trial_result · 2018-04-02Clinical Trial Update: Clofarabine Plus Cytarabine Versus Conventional Induction Therapy And A Study Of NK Cell Transplantation In Newly Diagnosed Acute Myeloid Leukemia [Phase 3]
Phase 3 trial comparing clofarabine plus cytarabine against conventional induction therapy in newly diagnosed acute myeloid leukemia; also s…