Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2018-07-24Clinical Trial Update: Safety and Efficacy Study of PD-616 Plus Cytarabine to Treat Acute Myelogenous Leukemia or Myelodysplastic Syndrome [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating PD-616 in combination with cytarabine for acute myeloid leukemia and myelodysplastic syndromes has bee…
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FDA approval · 2018-07-20FDA Approved: TIBSOVO — Original Application (Servier Pharmaceutical LLC)
FDA approved Tibsovo (ivosidenib) in its original application for the treatment of acute myeloid leukemia, supporting use in patients with I…
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CLINICAL_TRIALS trial_result · 2018-07-19Clinical Trial Update: Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer
This Clinical Trial Update describes a study collecting and storing malignant and related samples from young cancer patients; the trial stat…
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Adoptive Transfer of Haplo-identical DLI for AML and MDS [Phase 1, Phase 2]
Clinical trial update for adoptive transfer of haplo-identical donor lymphocyte infusion in AML and MDS, completed with posted results in 20…
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CLINICAL_TRIALS research · 2018-07-18Clinical Trial Update: Chidamide Plus PTCy/Cyclosporine to Prevent GVHD After Myeloablative Conditioning, Matched PBSCT [Phase 2]
Phase 2 clinical trial evaluating chidamide plus post-transplant cyclophosphamide and cyclosporine to prevent graft-versus-host disease afte…
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FDA approval · 2018-07-17FDA Approved: CYTARABINE — Original Application (Meitheal Pharmaceuticals Inc.)
FDA approves the original application for CYTARABINE (cytarabine) from Meitheal Pharmaceuticals Inc., making a generic cytarabine product av…
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CLINICAL_TRIALS research · 2018-07-12Clinical Trial Update: NGS in AML Relapse
This entry provides an update on a clinical trial investigating the use of next-generation sequencing in relapsed acute myeloid leukemia at …
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Ultra-Low Dose IL-2 Therapy as GVHD Prophylaxis in Haploidentical Allogeneic Stem Cell Transplantation [Phase 1]
Phase 1 trial update reporting completion of a study evaluating ultra-low-dose interleukin-2 as graft-versus-host disease prophylaxis in hap…
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: E7070, Idarubicin and Cytarabine in Relapsed AML and High-Risk Myelodysplastic Syndromes [Phase 2]
Phase 2 clinical trial evaluating E7070 in combination with idarubicin and cytarabine for relapsed acute myeloid leukemia and high-risk myel…
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: CPI-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 trial evaluating CPI-613 (devimistat) in combination with cytarabine and mitoxantrone hydrochloride for relapsed or refractory acute…
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CLINICAL_TRIALS withdrawal · 2018-07-03Clinical Trial Update: 6,8-Bis(Benzylthio)Octanoic Acid, Cytarabine, and Daunorubicin Hydrochloride in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating 6,8-Bis(Benzylthio)Octanoic Acid in combination with Cytarabine and Daunorubicin hydrochloride for unt…
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CLINICAL_TRIALS research · 2018-07-02Clinical Trial Update: Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer [NA]
Clinical trial update on caregiver-delivered massage therapy to improve quality of life in pediatric cancer patients; the study (NCT01053494…
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CLINICAL_TRIALS trial_result · 2018-07-02Clinical Trial Update: Decitabine and Plerixafor in Elderly Acute Myeloid Leukemia (AML) [Phase 1]
Phase 1 trial update of decitabine in combination with plerixafor in elderly patients with acute myeloid leukemia.
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CLINICAL_TRIALS research · 2018-07-02Clinical Trial Update: Investigating the Prevalence and Prognostic Importance of Polypharmacy in Adults Treated for Newly Diagnosed Acute Myelogenous Leukemia (AML)
This clinical trial update summarizes a completed study examining the prevalence of polypharmacy in adults with newly diagnosed acute myeloi…
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FDA approval · 2018-07-02FDA Approved: AZACITIDINE — Original Application (Accord Healthcare Inc.)
FDA approved Accord Healthcare Inc.'s original application for azacitidine, providing a generic version of the cancer drug indicated for mye…
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CLINICAL_TRIALS withdrawal · 2018-07-02Clinical Trial Update: Gemtuzumab Ozogamicin in Treating Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 trial of gemtuzumab ozogamicin for adults with acute myeloid leukemia, including acute promyelocytic leukemia and various cytogeneti…
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CLINICAL_TRIALS trial_result · 2018-06-28Clinical Trial Update: Cladribine Dose Escalation in Conditioning Regimen Prior to Allo-HSCT for Refractory Acute Leukemia and Myelodysplastic Syndromes [Phase 1]
A Phase 1 trial update exploring dose escalation of cladribine in conditioning regimens before allogeneic stem cell transplantation for refr…
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Pilot Study of Feasibility of Outpatient Daily High Dose Cytarabine as Consolidation Therapy for Older Patients With Acute Myeloid Leukemia (AML) [NA]
This completed pilot study assesses the feasibility of outpatient daily high-dose cytarabine as consolidation therapy for older adults with …
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CLINICAL_TRIALS trial_result · 2018-06-15Clinical Trial Update: Pacritinib Combined With Decitabine or Cytarabine in Older Patients With AML [Phase 2]
Phase 2 trial evaluating pacritinib with decitabine or cytarabine in older patients with acute myeloid leukemia was terminated; results were…
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CLINICAL_TRIALS research · 2018-06-14Clinical Trial Update: CART-123 FOR Relapsed/Refractory Acute Myelocytic Leukemia（AML） [Phase 1, Phase 2]
Clinical trial update for CART-123 in relapsed/refractory acute myeloid leukemia, spanning Phase 1 and Phase 2. Current status of the trial …
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CLINICAL_TRIALS trial_result · 2018-06-12Clinical Trial Update: Standard Idarubicin and Cytarabine for the Treatment of Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 clinical trial update evaluating standard idarubicin and cytarabine for acute myeloid leukemia has completed with results posted in …
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: Relapsed Malignant Blood Cancer After Allogeneic Hematopoietic Stem Cell Transplantation
The National Cancer Institute-sponsored clinical trial assessing relapse in malignant blood cancers after allogeneic hematopoietic stem cell…
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CLINICAL_TRIALS trial_result · 2018-06-04Clinical Trial Update: Dose Escalation of OXi4503 as Single Agent and Combination With Cytarabine w/Subsequent Ph 2 Cohorts for AML and MDS [Phase 1, Phase 2]
Dose-escalation study of OXi4503 as a single agent and in combination with cytarabine, with subsequent Phase 2 cohorts planned for acute mye…
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CLINICAL_TRIALS trial_result · 2018-06-01Clinical Trial Update: Safety Study of Chimeric Antigen Receptor Modified T-cells Targeting NKG2D-Ligands [Phase 1]
Phase 1 safety study of CYAD-01, CAR T cells targeting NKG2D-ligands, completed; evaluated in acute myeloid leukemia, myelodysplastic syndro…
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CLINICAL_TRIALS trial_result · 2018-05-30Clinical Trial Update: Omacetaxine and Low Dose Cytarabine in Older Patients With Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 trial of omacetaxine with low-dose cytarabine in older patients with acute myeloid leukemia and high-risk myelodysplastic syndrome h…