Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-10-09Clinical Trial Update: Eltrombopag Used in Thrombocytopenia After Comsolidation Therapy in AML [Phase 2, Phase 3]
Phase 2/Phase 3 trial updates explore eltrombopag for thrombocytopenia after consolidation therapy in acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2018-10-03Clinical Trial Update: Study of MLN9708 as Maintenance Therapy for Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS) in Remission [Phase 2]
Phase 2 trial of MLN9708 as maintenance therapy in AML and high-risk MDS patients in remission was terminated; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-10-02Clinical Trial Update: WT1 TCR Gene Therapy for Leukaemia: A Phase I/II Safety and Toxicity Study [Phase 1, Phase 2]
A Phase I/II safety and toxicity study of WT1 TCR gene therapy for acute myeloid leukemia and chronic myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2018-10-02Clinical Trial Update: Genomic Predictors of Decitabine Response in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes [Phase 2]
Phase 2 trial update evaluating genomic predictors of decitabine response in patients with acute myeloid leukemia or myelodysplastic syndrom…
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CLINICAL_TRIALS trial_result · 2018-10-01Clinical Trial Update: A Dose-finding Study of the Bromodomain (Brd) Inhibitor OTX015/ Birabresib (MK-8628) in Hematologic Malignancies (MK-8628-001) [Phase 1]
Phase 1 dose-finding study of the bromodomain inhibitor birabresib (OTX015/MK-8628) in hematologic malignancies has completed with results p…
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FDA approval · 2018-09-28FDA Approved: BUSULFEX — Supplemental Application (Otsuka America Pharmaceutical, Inc.)
FDA approved a supplemental application for Busultex (busulfan) filed by Otsuka America Pharmaceutical, Inc. The action updates the labeling…
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FDA approval · 2018-09-27FDA Approved: DAUNORUBICIN HYDROCHLORIDE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved a supplemental application for daunorubicin hydrochloride (Hikma Pharmaceuticals USA Inc.).
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CLINICAL_TRIALS trial_result · 2018-09-27Clinical Trial Update: Safety and Efficacy of Human Myeloid Progenitor Cells (CLT-008) During Chemotherapy for Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial update on safety and efficacy of CLT-008 human myeloid progenitor cells during chemotherapy in acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2018-09-26Clinical Trial Update: Experimental Bone Marrow Transplant Protocol [Phase 2]
Phase 2 clinical trial update for an experimental bone marrow transplant protocol that investigated treatment in blood cancer conditions; st…
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CLINICAL_TRIALS trial_result · 2018-09-20Clinical Trial Update: A Study of Lenalidomide in Pediatric Subjects With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 study evaluating lenalidomide in pediatric patients with relapsed or refractory acute myeloid leukemia has completed with posted res…
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CLINICAL_TRIALS trial_result · 2018-09-07Clinical Trial Update: Decitabine and Midostaurin in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 2]
Phase 2 trial update evaluating decitabine and midostaurin in older adults with newly diagnosed acute myeloid leukemia; study status termina…
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CLINICAL_TRIALS research · 2018-09-07Clinical Trial Update: WT1 Immunity Via DNA Fusion Gene Vaccination in Haematological Malignancies by Intramuscular Injection Followed by Intramuscular Electroporation [Phase 2]
Phase 2 clinical trial investigating WT1 DNA fusion gene vaccination with intramuscular injection and electroporation for haematological mal…
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CLINICAL_TRIALS trial_result · 2018-09-05Clinical Trial Update: Phase 1/2 Study of the ERK1/2 Inhibitor BVD-523 in Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndromes [Phase 1, Phase 2]
Phase 1/2 study evaluating the ERK1/2 inhibitor BVD-523 (ulixertinib) in patients with acute myeloid leukemia or myelodysplastic syndromes; …
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CLINICAL_TRIALS trial_result · 2018-08-31Clinical Trial Update: HLA 10/10 Matched Unrelated Donor vs Haploidentical Allogenic Hematopoietic Stem Cell Transplantation [Phase 3]
Phase 3 trial comparing HLA 10/10 matched unrelated donor versus haploidentical allogeneic hematopoietic stem cell transplantation for acute…
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CLINICAL_TRIALS trial_result · 2018-08-22Clinical Trial Update: Combination of BTK Inhibitor Overcomes Drug-resistance in Refractory/Relapsed FLT3 Mutant AML [Phase 2, Phase 3]
A clinical trial update reports a BTK inhibitor combination aimed at overcoming drug resistance in refractory/relapsed FLT3-mutant acute mye…
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CLINICAL_TRIALS trial_result · 2018-08-17Clinical Trial Update: Phase I/II Study of Combination of Sorafenib, Vorinostat, and Bortezomib for the Treatment of Acute Myeloid Leukemia With Complex- or Poor-risk (Monosomy 5/7) Cytogenetics or FLT3-ITD Positive Genotype [Phase 1, Phase 2]
Phase I/II trial evaluating a combination of sorafenib, vorinostat, and bortezomib in adults with acute myeloid leukemia, completed with pos…
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CLINICAL_TRIALS trial_result · 2018-08-14Clinical Trial Update: Study of Ibrutinib in Subjects With Acute Myeloid Leukemia [Phase 2]
Phase 2 trial of ibrutinib in acute myeloid leukemia was terminated; results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-08-07Clinical Trial Update: Evaluation of a New Anti-cancer Immunotherapy After Chemotherapy in Adult Patients With Acute Myeloid Leukemia (AML) [Phase 1]
Phase 1 trial evaluating a new anti-cancer immunotherapy after chemotherapy in adults with acute myeloid leukemia has completed with posted …
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CLINICAL_TRIALS trial_result · 2018-08-06Clinical Trial Update: Risk-adapted, MRD-directed Therapy for Young Adults With Newly Diagnosed Acute Myeloid Leukemia [Phase 2]
A Phase 2 trial updating risk-adapted, MRD-directed therapy for young adults with newly diagnosed acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2018-08-01Clinical Trial Update: Study of Low-Dose Cytarabine and Etoposide With or Without All-Trans Retinoic Acid in Older Patients Not Eligible for Intensive Chemotherapy With Acute Myeloid Leukemia and NPM1 Mutation [Phase 3]
Phase 3 trial evaluating low-dose cytarabine and etoposide with or without all-trans retinoic acid in older AML patients not eligible for in…
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CLINICAL_TRIALS trial_result · 2018-07-31Clinical Trial Update: Use Feasibility of the iThermonitor in Pediatrics Patients on Myelosuppresive Therapies [NA]
Clinical trial update evaluating the feasibility of the iThermonitor in pediatric patients receiving myelosuppressive therapies; the study i…
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CLINICAL_TRIALS trial_result · 2018-07-30Clinical Trial Update: Volasertib in Japanese Patients With Acute Myeloid Leukemia (AML) [Phase 1]
Phase 1 study of volasertib in Japanese patients with acute myeloid leukemia; the report covers safety, tolerability, and preliminary activi…
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: AML Therapy With Irradiated Allogeneic Cells [NA]
Clinical trial update for irradiated allogeneic cell therapy in various adult acute myeloid leukemia subtypes; the study is terminated with …
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CLINICAL_TRIALS approval · 2018-07-24Clinical Trial Update: Ivosidenib Expanded Access Program in Relapsed/Refractory AML With an IDH1 Mutation
This clinical trial update describes an expanded access program for Ivosidenib in relapsed/refractory IDH1-mutant acute myeloid leukemia. It…
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CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: Choline Magnesium Trisalicylate and Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 trial updating the use of Choline Magnesium Trisalicylate in combination chemotherapy for various adult acute myeloid leukemia subty…