Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-12-05Clinical Trial Update: 8-Chloroadenosine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
A phase 1/2 clinical trial investigates 8-Chloroadenosine for relapsed or refractory acute myeloid leukemia, with completed results posted i…
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CLINICAL_TRIALS trial_result · 2023-11-30Clinical Trial Update: A Phase II Study of Crenolanib in Relapsed/Refractory Acute Myeloid Leukemia Patients With FLT3 Activating Mutations [Phase 2]
Phase II study of crenolanib in relapsed/refractory FLT3-mutated acute myeloid leukemia completed with posted results.
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CLINICAL_TRIALS trial_result · 2023-11-29Clinical Trial Update: CART-19 T Cell in CD19 Positive Relapsed or Refractory Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating CART-19 T cell therapy targeting CD19 in patients with relapsed or refractory acute myeloid leukemia (…
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CLINICAL_TRIALS trial_result · 2023-11-28Clinical Trial Update: CAR-T CD19 for Acute Myelogenous Leukemia With t 8:21 and CD19 Expression [Phase 2, Phase 3]
A clinical trial update involving CAR-T therapy targeting CD19 for acute myeloid leukemia across Phase 2 and Phase 3 stages.
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CLINICAL_TRIALS trial_result · 2023-11-28Clinical Trial Update: Venetoclax Plus RIC Regimen Allo-HSCT for Elderly Patients With High-risk Myeloid Malignancies [Phase 2]
Phase 2 clinical trial evaluating venetoclax plus reduced-intensity conditioning allogeneic stem cell transplantation in elderly patients wi…
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CLINICAL_TRIALS trial_result · 2023-11-28Clinical Trial Update: Bisantrene Combination for Resistant AML [Phase 2]
Phase 2 clinical trial update for a bisantrene combination in resistant acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: Clinical Study of Venetoclax Combined With CAG in the Treatment of Refractory/Relapsed Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical study evaluating venetoclax in combination with CAG for refractory/relapsed acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: Plerixafor Plus Donor Lymphocyte Infusion for Relapsed Acute Leukemia After Allo-HSCT [Phase 2]
Phase 2 clinical trial update evaluating plerixafor in combination with donor lymphocyte infusion for relapsed acute leukemia after allogene…
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: Phase II Trial in Elderly Patients With AML or MDS in Complete Remission Not Eligible for Allogenic Transplant [Phase 2]
Phase II clinical trial in elderly patients with acute myeloid leukemia or myelodysplastic syndromes in complete remission not eligible for …
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CLINICAL_TRIALS trial_result · 2023-11-15Clinical Trial Update: Isatuximab in Combination With Chemotherapy in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia [Phase 2]
Phase 2 pediatric trial evaluating Isatuximab in combination with chemotherapy for relapsed/refractory acute lymphoblastic leukemia or acute…
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: Donor Natural Killer Cells and Donor Stem Cell Transplant in Treating Patients With High Risk Myeloid Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating donor natural killer cells and donor stem cell transplant in high-risk myeloid malignancies; completed w…
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: Multi-Ctr PII Cmb.Modality Tx Ruxolitinib, Decitabine, and DLI for Post HSCT in AML/MDS [Phase 2]
Phase 2 trial update of multi-modality treatment with Ruxolitinib, Decitabine, and donor lymphocyte infusion after stem cell transplant in A…
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: Study of Milademetan in Japanese Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) [Phase 1]
Phase 1 trial of milademetan in Japanese patients with relapsed or refractory acute myeloid leukemia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-11-03Clinical Trial Update: Relapse Prophylaxis With N-803 for AML and MDS Pts Following Allo HSCT [Phase 2]
Phase 2 trial investigating relapse prophylaxis with N-803 after allogeneic HSCT in AML and MDS patients has completed with posted results.
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CLINICAL_TRIALS trial_result · 2023-10-30Clinical Trial Update: Safety and Efficacy of Unrelated Umbilical Cord Blood Microtransplantation in Patients With AML [Phase 2]
Phase 2 trial evaluating safety and efficacy of unrelated umbilical cord blood microtransplantation in patients with acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2023-10-26Clinical Trial Update: Immunochemotherapy and AlloSCT in Patients With High Risk CD33+ AML/MDS [Phase 2]
Phase 2 clinical trial evaluating immunochemotherapy and allogeneic stem cell transplantation in high-risk CD33+ acute myeloid leukemia and …
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CLINICAL_TRIALS trial_result · 2023-10-26Clinical Trial Update: SCT Plus Immune Therapy in Average Risk AML/MDS [Phase 2]
Phase 2 clinical trial update for SCT plus immune therapy in average-risk acute myeloid leukemia and myelodysplastic syndrome has completed.
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CLINICAL_TRIALS trial_result · 2023-10-25Clinical Trial Update: A Study of APG-2575 in Combination With Azacitidine in Patients With Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
Clinical trial update for APG-2575 in combination with azacitidine in adults with acute myeloid leukemia, spanning Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: Biomarkers in Predicting Treatment Response to Sirolimus and Chemotherapy in Patients With High-Risk Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating biomarkers predicting response to sirolimus plus chemotherapy in high-risk acute myeloid leukemia; trial completed.
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: Comparison of the Efficacy and Safety of Venetoclax in Combination With 3 Days Decitabine (DEC3-VEN) vs. Venetoclax in Combination With Azacitidine (VIALE-A) in the Treatment of Elderly Patients or Unfit, New-diagnosis Acute Myeloid Leukemia Patients [Phase 3]
A Phase 3 trial comparing venetoclax plus decitabine (DEC3-VEN) versus venetoclax plus azacitidine (VIALE-A) in elderly or unfit, newly diag…
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CLINICAL_TRIALS trial_result · 2023-10-05Clinical Trial Update: Safety & Activity of Controllable PRAME-TCR Therapy in Previously Treated AML/MDS or Metastatic Uveal Melanoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating controllable PRAME-TCR therapy in patients with acute myeloid leukemia, myelodysplastic syndrome, or metastatic u…
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CLINICAL_TRIALS trial_result · 2023-10-03Clinical Trial Update: Phase I/IIa Trial to Investigate BI 6727 (Volasertib) as Monotherapy or in Combination With Cytarabine in Acute Myeloid Leukaemia [Phase 2]
Phase 2 trial of BI 6727 (volasertib) as monotherapy or with cytarabine in acute myeloid leukemia has completed with posted results.
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CLINICAL_TRIALS trial_result · 2023-09-29Clinical Trial Update: Ribavirin and Hedgehog Inhibitor With or Without Decitabine in AML [Phase 2]
Phase 2 clinical trial evaluating ribavirin and Hedgehog pathway inhibitor with or without decitabine in acute myeloid leukemia has complete…
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: CPX-351 Plus Enasidenib for Relapsed AML [Phase 2]
Phase 2 clinical trial update evaluating CPX-351 in combination with enasidenib for relapsed/refractory acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Methods of T Cell Depletion Trial (MoTD) [Phase 2]
Phase 2 trial update for methods of T cell depletion in various hematologic malignancies is ongoing.