Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-09-26Clinical Trial Update: Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study [Phase 1, Phase 2]
Long-term follow-up update from BP-004 study (Phase 1/Phase 2) by Bellicum Pharmaceuticals; study status TERMINATED with results posted in 2…
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CLINICAL_TRIALS trial_result · 2023-09-22Clinical Trial Update: Lymphodepletion and Anti-PD-1 Blockade to Reduce Relapse in AML Patient Not Eligible for Transplant [Phase 2]
Phase 2 clinical trial evaluating lymphodepletion plus anti-PD-1 blockade to reduce relapse in acute myeloid leukemia patients ineligible fo…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Daratumumab in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating daratumumab in relapsed or high-risk myeloid malignancies (high-risk myelodysplastic syndrome and recurrent/refract…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Allo HSCT Using RIC for Hematological Diseases [Phase 2]
Phase 2 trial evaluating allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning for various hematologic dise…
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CLINICAL_TRIALS trial_result · 2023-09-18Clinical Trial Update: A Study of Pevonedistat and Venetoclax Combined With Azacitidine to Treat Acute Myeloid Leukemia (AML) in Adults Unable to Receive Intensive Chemotherapy [Phase 2]
Phase 2 results for a combo of pevonedistat, venetoclax, and azacitidine in adults with acute myeloid leukemia who cannot receive intensive …
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CLINICAL_TRIALS trial_result · 2023-09-18Clinical Trial Update: Pixantrone (BBR 2778) in Patients With Refractory Acute Myelogenous Leukemia (AML) [Phase 1, Phase 2]
Phase 1/2 trial of pixantrone (BBR 2778) in refractory acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: Comparison Between Two Dose Levels of Daunorubicin and Between One vs. Two Induction Cycles for Adult Patients With AML [Phase 3]
Phase 3 trial comparing two daunorubicin dose levels and one versus two induction cycles in adult acute myeloid leukemia patients has comple…
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CLINICAL_TRIALS trial_result · 2023-09-14Clinical Trial Update: A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor [Phase 2]
Phase II trial evaluating safety and efficacy of subcutaneous plerixafor in related donors of peripheral blood stem cells for various hemato…
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CLINICAL_TRIALS trial_result · 2023-09-14Clinical Trial Update: Clofarabine Pre-conditioning Followed by Stem Cell Transplant for Non-remission AML [Phase 2]
Phase 2 trial evaluating clofarabine pre-conditioning followed by stem cell transplant in acute myeloid leukemia; study terminated with resu…
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: Itacitinib, Tacrolimus, and Sirolimus for the Prevention of GVHD in Patients With Acute Leukemia, Myelodysplastic Syndrome, or Myelofibrosis Undergoing Reduced Intensity Conditioning Donor Stem Cell Transplantation [Phase 2]
Phase 2 study evaluating a combination of Itacitinib, Tacrolimus, and Sirolimus for prevention of graft-versus-host disease in patients with…
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: Study Augmenting TAK-659 Action in Relapsed/Refractory AML by Addition Ofthe Proteasome Inhibitor Ixazomib [Phase 1, Phase 2]
Phase 1/2 trial investigating TAK-659 in combination with Ixazomib for relapsed/refractory acute myeloid leukemia; study status terminated w…
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CLINICAL_TRIALS trial_result · 2023-09-01Clinical Trial Update: Study of Haplo-HSCT + Rivogenlecleucel vs Haplo-HSCT + Post Transplant Cyclophosphamide in Patients With AML or MDS [Phase 2, Phase 3]
A study comparing Haplo-HSCT with Rivogenlecleucel versus Haplo-HSCT with post-transplant cyclophosphamide in AML or MDS was terminated with…
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CLINICAL_TRIALS trial_result · 2023-09-01Clinical Trial Update: Study of Emerfetamab (AMG 673) in Adults With Relapsed/Refractory Acute Myeloid Leukemia (AML) [EARLY_Phase 1]
Early-phase trial of Emerfetamab (AMG 673) in adults with relapsed/refractory acute myeloid leukemia was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2023-08-09Clinical Trial Update: A Study of ARGX-110 in Combination With Azacytidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) or High Risk Myelodysplatic Syndrome (MDS) [Phase 1, Phase 2]
Phase 1/2 trial evaluating ARGX-110 with azacytidine in newly diagnosed acute myeloid leukemia or high-risk myelodysplastic syndromes has co…
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CLINICAL_TRIALS trial_result · 2023-08-04Clinical Trial Update: Sorafenib and Low Dose Cytarabine in Older Patients With Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
Clinical trial updating sorafenib combined with low-dose cytarabine in older patients with acute myeloid leukemia or high-risk myelodysplast…
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CLINICAL_TRIALS trial_result · 2023-08-04Clinical Trial Update: Venetoclax and Lintuzumab-Ac225 in AML Patients [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating venetoclax in combination with lintuzumab-acy225 for relapsed or adult acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: 2018-0674 - IL-7 for T-Cell Recovery Post Haplo and CB Transplant - Phase I/II [Phase 1, Phase 2]
This Phase I/II clinical trial evaluated Interleukin-7 for T-cell recovery after haploidentical and cord blood stem cell transplantation and…
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: Ibrutinib in Preventing Acute Leukemia in Patients After Reduced-Intensity Conditioning and Stem Cell Transplant [Phase 2]
Phase 2 trial evaluating ibrutinib to prevent acute leukemia after reduced-intensity conditioning and stem cell transplant.
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: Efficacy and Safety of BST-236 in Newly Diagnosed Acute Myeloid Leukemia Patients, Unfit for Standard Induction Therapy [Phase 2]
Phase 2 trial updates efficacy and safety of BST-236 in newly diagnosed acute myeloid leukemia patients unfit for standard induction therapy…
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: Treateament of Newly Diagnosed Acute Monocytic Leukemia in Children [Phase 2, Phase 3]
Clinical trial update for treatment of newly diagnosed acute monocytic leukemia in children, currently in Phase 2 and Phase 3.
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FDA approval · 2023-07-20FDA Approved: VANFLYTA — Original Application (Daiichi Sankyo Inc.)
FDA approved VANFLYTA (quizartinib) for adults with newly diagnosed FLT3-ITD–positive acute myeloid leukemia in combination with standard in…
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CLINICAL_TRIALS trial_result · 2023-07-20Clinical Trial Update: Lintuzumab-Ac225 in Older Acute Myeloid Leukemia (AML) Patients [Phase 1, Phase 2]
Phase 1/2 trial results for lintuzumab-Ac225 in older adults with acute myeloid leukemia have been completed.
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CLINICAL_TRIALS trial_result · 2023-07-19Clinical Trial Update: Study of Selinexor Combined With Chidamide in Relapsed/Refractory Acute Leukemia (AML) Patients [Phase 2]
Phase 2 trial evaluating selinexor with chidamide for relapsed/refractory acute myeloid leukemia is in progress, status currently unknown.
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CLINICAL_TRIALS trial_result · 2023-07-19Clinical Trial Update: Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia [Phase 3]
Phase 3 trial comparing Iomab-B to conventional care in older patients with active, relapsed or refractory acute myeloid leukemia is ongoing…
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CLINICAL_TRIALS trial_result · 2023-07-18Clinical Trial Update: Safety and Efficacy of Venetoclax in Combination With Azacitidine and HA Regimen in the Treatment of AML in the Elderly [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating venetoclax with azacitidine and HA regimen for elderly patients with acute myeloid leukemia; current s…