Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-02-08Clinical Trial Update: Fractionated Gemtuzumab Ozogamicin Followed by Non-engraftment Donor Leukocyte Infusions for Relapsed/Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating fractionated gemtuzumab ozogamicin followed by non-engraftment donor leukocyte infusions in relapsed/refractory acu…
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: Gemtuzumab Ozogamicin+Cytarabine vs Idarubicin+Cytarabine in Elderly Patients With AML.Mylofrance 4 [Phase 2, Phase 3]
A clinical trial comparing gemtuzumab ozogamicin plus cytarabine versus idarubicin plus cytarabine in elderly patients with acute myeloid le…
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: A Safety and Tolerability Study of Crenolanib in Combination With Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia Patients With FLT3 Mutations [Phase 2]
Phase 2 safety and tolerability study of crenolanib with chemotherapy in newly diagnosed AML patients with FLT3 mutations completed; results…
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: A Study of APG-115 Alone or Combined With Azacitidine in Patients With AML, CMML, or MDS [Phase 1, Phase 2]
Clinical trial update on APG-115 alone or with azacitidine in patients with AML, CMML, or MDS across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: Clofarabine and Low Dose Total Body Irradiation as a Preparative Regimen for Stem Cell Transplant in Leukemia. [Phase 1]
Phase 1 trial of clofarabine with low-dose total body irradiation as a preparative regimen for stem cell transplant in leukemia shows comple…
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic Transplant [Phase 1]
Phase 1 trial evaluating the CMV-MVA Triplex vaccine given to stem cell donors to prevent cytomegalovirus viremia in recipients of allogenei…
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: Comparison of the OSHO Protocol to a Standard Arm Protocol of the German AML Intergroup in Patients With AML>60a [Phase 3]
Phase 3 trial comparing the OSHO protocol to a standard arm in adults over 60 with acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy [Phase 2]
Phase 2 clinical trial update for MGTA-456 in high-risk hematologic malignancies; results were posted in 2024 and the study is currently act…
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: DS-3201b for Acute Myelogenous Leukemia (AML) or Acute Lymphocytic Leukemia (ALL) [Phase 1]
Phase 1 trial update for DS-3201b in acute myeloid leukemia and acute lymphocytic leukemia has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Flotetuzumab in Primary Induction Failure (PIF) or Early Relapse (ER) Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
Phase 1/2 clinical trial update for flotetuzumab in primary induction failure or early relapse acute myeloid leukemia; the study is terminat…
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CLINICAL_TRIALS trial_result · 2024-01-29Clinical Trial Update: Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia [Phase 2, Phase 3]
Clinical trial update for stem cell transplant in acute myeloid leukemia is terminated with results posted.
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CLINICAL_TRIALS trial_result · 2024-01-23Clinical Trial Update: A Study of TQB3454 Tablets in Patients With Blood Tumors [Phase 1, Phase 2]
Clinical trial update for TQB3454 tablets in blood tumors (Phase 1/2) involving Acute Myeloid Leukemia and Myelodysplastic Syndromes.
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CLINICAL_TRIALS trial_result · 2024-01-19Clinical Trial Update: Impact of Remission Induction Chemotherapy Prior to Allogeneic SCT in Relapsed and Poor-response Patients With AML [Phase 3]
Phase 3 trial assessing whether remission induction chemotherapy before allogeneic stem cell transplant improves outcomes in relapsed or poo…
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CLINICAL_TRIALS trial_result · 2024-01-18Clinical Trial Update: Comparison of Consolidation Strategies for Pediatric Patients With Acute Myeloid Leukemia [Phase 3]
Phase 3 trial update comparing consolidation strategies for pediatric acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2024-01-17Clinical Trial Update: Natural Killer Cells Before and After Donor Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating natural killer cells as part of donor stem cell transplantation for various myeloid leukemias and myelodysplastic…
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CLINICAL_TRIALS trial_result · 2024-01-17Clinical Trial Update: Allogeneic Hematopoietic Stem Cell Transplantation (AlloSCT) Initial Salvage Therapy for Induction Failure Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 trial evaluating allogeneic hematopoietic stem cell transplantation as initial salvage therapy for induction failure in acute myeloi…
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CLINICAL_TRIALS trial_result · 2024-01-16Clinical Trial Update: Antigen-specific T Cell Therapy for AML or MDS Patients With Relapsed Disease After Allo-HCT [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating an antigen-specific T cell therapy for patients with acute myeloid leukemia or myelodysplastic syndrom…
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CLINICAL_TRIALS trial_result · 2023-12-28Clinical Trial Update: FLYSYN in MRD Positive AML [Phase 1, Phase 2]
Clinical trial update for FLYSYN in MRD-positive acute myeloid leukemia completed phases 1 and 2.
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CLINICAL_TRIALS trial_result · 2023-12-28Clinical Trial Update: Study Investigating NTLA-5001 in Subjects With Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 clinical trial of NTLA-5001 in Acute Myeloid Leukemia has been terminated; results posted previously.
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CLINICAL_TRIALS trial_result · 2023-12-28Clinical Trial Update: A Bridging Study of Liposomal Cytarabine-Daunorubicin in Treating Olderly Patients With Treatment-naive High-Risk (Secondary) Acute Myeloid Leukemia [Phase 3]
A Phase 3 bridging study evaluating liposomal cytarabine-daunorubicin for older patients with treatment-naive high-risk secondary acute myel…
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FDA approval · 2023-12-21FDA Approved: IDHIFA — Supplemental Application (Celgene Corporation)
FDA approved a supplemental application for IDHIFA (enasidenib mesylate) to expand its labeling for acute myeloid leukemia with IDH2 mutatio…
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CLINICAL_TRIALS trial_result · 2023-12-20Clinical Trial Update: Pilot Study of Crenolanib Combined With Standard Salvage Chemotherapy in Subjects With R/R AML [Phase 1, Phase 2]
Pilot study results for crenolanib combined with salvage chemotherapy in relapsed/refractory acute myeloid leukemia (AML) reported in a Phas…
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: Continuation Study of B1371019(NCT03416179) and B1371012(NCT02367456) Evaluating Azacitidine With Or Without Glasdegib In Patients With Previously Untreated AML, MDS or CMML [Phase 3]
Phase 3 continuation study of azacitidine with or without glasdegib in untreated AML, MDS, or CMML; trial completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: Crenolanib Maintenance Following Allogeneic Stem Cell Transplantation in FLT3-positive Acute Myeloid Leukemia Patients [Phase 2]
Phase 2 trial update evaluating crenolanib as maintenance therapy after allogeneic stem cell transplantation in FLT3-positive acute myeloid …
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CLINICAL_TRIALS trial_result · 2023-12-11Clinical Trial Update: Flotetuzumab for the Treatment of Pediatric Recurrent or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial of Flotetuzumab in pediatric patients with recurrent or refractory acute myeloid leukemia; results were posted in Dec…