Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-04-15Clinical Trial Update: Dociparstat in Combination With Standard Chemotherapy for the Treatment of Acute Myeloid Leukemia [Phase 3]
Phase 3 trial update for dociparstat in combination with standard chemotherapy in acute myeloid leukemia; study terminated with results post…
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CLINICAL_TRIALS trial_result · 2024-04-15Clinical Trial Update: A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of TJ011133 as Monotherapy and in Combination With Azacitidine (AZA) in Patients With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) [Phase 1, Phase 2]
A Phase 1/2 trial evaluating TJ011133 as monotherapy and in combination with azacitidine in AML or MDS has completed.
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CLINICAL_TRIALS trial_result · 2024-04-10Clinical Trial Update: MA+AZA Regimen for the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML) [Phase 3]
Phase 3 clinical trial evaluating MA+AZA regimen for newly diagnosed acute myeloid leukemia is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-04-10Clinical Trial Update: Innate Donor Effector Allogeneic Lymphocyte Infusion After Stem Cell Transplantation: the IDEAL Trial [Phase 2, Phase 3]
Clinical trial update for IDEAL trial evaluating innate donor effector allogeneic lymphocyte infusion after stem cell transplantation in AML…
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CLINICAL_TRIALS trial_result · 2024-04-10Clinical Trial Update: Venetoclax Add in Combination With Fludarabine, Cyratabine and Idarubicine in Induction for Acute Myelid Leukemia [Phase 2]
Phase 2 clinical trial investigating venetoclax in combination with fludarabine, cytarabine, and idarubicin (also known as FLAG-IDA) for ind…
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CLINICAL_TRIALS trial_result · 2024-04-09Clinical Trial Update: VA vs DA for Newly Diagnosed Hig-risk AML [Phase 2, Phase 3]
A clinical trial comparing VA versus DA for newly diagnosed high-risk acute myeloid leukemia is in Phase 2 and Phase 3 and currently recruit…
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CLINICAL_TRIALS trial_result · 2024-04-09Clinical Trial Update: A Pilot RCT of the PRISM Intervention for AYAs With Cancer [Phase 2]
pilot randomized Phase 2 trial evaluating the PRISM intervention for adolescents and young adults with cancer, completed.
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia [Phase 2]
Phase 2 trial update evaluating topotecan hydrochloride and carboplatin with or without veliparib for advanced myeloproliferative disorders …
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer [Phase 2]
Phase 2 study evaluating a conditioning regimen of fludarabine phosphate, cyclophosphamide, and total body irradiation followed by donor ste…
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FDA approval · 2024-03-29FDA Approved: AZACITIDINE — Supplemental Application (Accord Healthcare Inc.)
FDA approved a supplemental application for azacitidine from Accord Healthcare Inc., enabling continued regulatory authorization of the gene…
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CLINICAL_TRIALS trial_result · 2024-03-26Clinical Trial Update: APR-246 in Combination With Azacitidine for TP53 Mutated AML (Acute Myeloid Leukemia) or MDS (Myelodysplastic Syndromes) Following Allogeneic Stem Cell Transplant [Phase 2]
Phase 2 clinical trial update reporting results for APR-246 in combination with azacitidine for TP53-mutated acute myeloid leukemia or myelo…
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CLINICAL_TRIALS trial_result · 2024-03-20Clinical Trial Update: Study of Crenolanib Combined With Chemotherapy in FLT3-mutated Acute Myeloid Leukemia Patients [Phase 1, Phase 2]
The Phase 1/2 trial evaluating crenolanib in combination with chemotherapy for FLT3-mutated acute myeloid leukemia has completed enrollment …
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CLINICAL_TRIALS trial_result · 2024-03-19Clinical Trial Update: A Trial to Find and Investigate a Safe Dose of BI 836858 in Combination With Decitabine for Patients With Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
A combined Phase 1/2 trial evaluating BI 836858 with decitabine in adults with acute myeloid leukemia has completed, with results posted in …
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children [Phase 2]
Phase 2 trial exploring selective depletion of CD45RA+ T cells from allogeneic stem cell grafts to prevent GVHD in children has completed wi…
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Efficacy Study of Dendritic Cell Vaccination in Patients With Acute Myeloid Leukemia in Remission [Phase 2]
Phase 2 study evaluating dendritic cell vaccination as an efficacy treatment in patients with acute myeloid leukemia in remission.
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CLINICAL_TRIALS trial_result · 2024-03-08Clinical Trial Update: Study of AMG 330 in Combination With Pembrolizumab in Adult With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 study of AMG 330 in combination with pembrolizumab in adults with relapsed or refractory acute myeloid leukemia has been terminated;…
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CLINICAL_TRIALS trial_result · 2024-03-05Clinical Trial Update: A Patient-centered Communication Tool (UR-GOAL) for Older Patients With Acute Myeloid Leukemia, Their Caregivers, and Their Oncologists [NA]
A completed clinical trial evaluating UR-GOAL, a patient-centered communication tool for older adults with Acute Myeloid Leukemia, their car…
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CLINICAL_TRIALS trial_result · 2024-02-29Clinical Trial Update: Safety and Efficacy of Venetoclax Combination With Decitabine(DEC3-VEN) in the Treatment of AML in the Adult [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating venetoclax in combination with decitabine for adult acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2024-02-29Clinical Trial Update: Rapamycin in Combination With Low-dose Aracytin in Elderly Acute Myeloid Leukemia Patients [Phase 2]
Phase 2 trial evaluating rapamycin combined with low-dose cytarabine in elderly patients with acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Quizartinib With Azacitidine or Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1, Phase 2]
Phase 1/2 trial evaluating quizartinib with azacitidine or cytarabine in relapsed or refractory acute myeloid leukemia and myelodysplastic s…
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Trial for Relapsed or Refractory AML Patients Combining Cytarabine and Mitoxantrone With Venetoclax (RELAX) [Phase 1, Phase 2]
Phase 1/2 trial evaluating cytarabine and mitoxantrone with venetoclax for relapsed or refractory acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2024-02-23Clinical Trial Update: Randomized Phase III Study of Intensive Chemotherapy With or Without Dasatinib (Sprycel™) [Phase 3]
Randomized Phase III trial evaluating intensive chemotherapy with or without dasatinib (Sprycel) in acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2024-02-22Clinical Trial Update: Investigator Initiated Trial of CPX-351 for Untreated Acute Myeloid Leukemia [Phase 2]
Phase 2 investigator-initiated trial of CPX-351 in untreated acute myeloid leukemia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-02-13Clinical Trial Update: IPA Targeted Adoptive Immunotherapy vs Adult Haplo-identical Cell Infusion During Induction of High Risk Leukemia [Phase 2]
Phase 2 trial evaluating IPA-targeted adoptive immunotherapy versus adult haplo-identical cell infusion for induction in high-risk leukemia;…
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CLINICAL_TRIALS trial_result · 2024-02-08Clinical Trial Update: Study to Assess the Safety and Efficacy of Midostaurin (PKC412) in Combination With Standard Chemotherapy During Induction and Consolidation Followed by 12 Months of Maintenance Monotherapy in Patients With Newly-diagnosed FMS-like Tyrosine 3 (FLT3) Kinase Receptor-mutated Acute Myeloid Leukemia. [Phase 3]
A Phase 3 trial evaluating midostaurin added to standard chemotherapy for newly diagnosed FLT3-mutated acute myeloid leukemia has completed …