Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Safety and Pharmacokinetics of Intravenous and Oral APX001 in Patients With Acute Myeloid Leukemia (AML) and Neutropenia [Phase 1]
Phase 1 study evaluating safety, tolerability, and pharmacokinetics of intravenous and oral APX001 (fosmanogepix) in patients with Acute Mye…
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CLINICAL_TRIALS research · 2024-05-17Clinical Trial Update: IMPACT-AML: Randomized Pragmatic Clinical Trial for Relapsed or Refractory AML [Phase 3]
IMPACT-AML is a Phase 3 randomized pragmatic trial evaluating treatment strategies for relapsed or refractory acute myeloid leukemia and is …
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: A Study of FMT in Patients With AML Allo HSCT in Recipients [Phase 2]
Phase 2 trial evaluating fecal microbiota transplantation in patients with acute myeloid leukemia undergoing allogeneic hematopoietic cell t…
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Study Protocol: Study on Incidence and Risk Factors of Mold Infections in Children During Leukemia Treatment
This document describes a protocol for a study to determine the incidence of mold infections in children undergoing leukemia treatment and i…
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FDA approval · 2024-05-16FDA Approved: AZACITIDINE — Original Application (Sandoz Inc)
FDA approved Sandoz Inc.'s generic azacitidine (AZACITIDINE) as an Original Application under ANDA212580.
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: A Study of HYML-122 in Patients With FLT3 Positive Relapsed or Refractory Acute Myeloid Leukemia (AML) [Phase 2]
A Phase 2 clinical trial evaluating HYML-122 for FLT3-positive relapsed or refractory acute myeloid leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Randomised Study of Oral Azacitidine vs Placebo Maintenance in AML or MDS Patients After Allo-SCT [Phase 3]
Phase 3 randomized trial evaluating oral azacitidine versus placebo as maintenance therapy after allogeneic stem cell transplantation in pat…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Low-dose AZA, Pioglitazone, ATRA Versus Standard-dose AZA in Patients >=60 Years With Refractory AML [Phase 2]
Phase 2 clinical trial update comparing low-dose azacitidine with pioglitazone and all-trans retinoic acid versus standard-dose azacitidine …
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Analysis of CMTM6 Expression in Patients With Acute Myeloid Leukemia
The completed clinical trial analyzes CMTM6 expression in adults with acute myeloid leukemia to evaluate its potential as a biomarker.
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: A Phase I Study of Euthare-155008(ETH-155008) in AML and NHL Patients [Phase 1]
A Phase I clinical trial update for ETH-155008 (Euthare-155008) in adult patients with non-Hodgkin lymphoma and recurrent acute myeloid leuk…
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Benadamustine, Fludarabine and Busulfan Conditioning in Recipients of Haploidentical Stem Cell Transplantation (FluBuBe) [Phase 2]
This Phase 2 clinical trial update reports on conditioning with benadamustine, fludarabine, and busulfan (FluBuBe) for recipients of haploid…
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CLINICAL_TRIALS trial_result · 2024-05-03Clinical Trial Update: A Study of LAM-003 in Patients With Acute Myeloid Leukemia [Phase 1]
This Phase 1 study of LAM-003 in patients with acute myeloid leukemia has completed enrollment and posted results.
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CLINICAL_TRIALS trial_result · 2024-05-03Clinical Trial Update: Trial of Haploidentical Stem Cell Transplantation for Haematological Cancers [Phase 2]
A Phase 2 clinical trial update on haploidentical stem cell transplantation for multiple hematologic cancers, with the study status reported…
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CLINICAL_TRIALS research · 2024-05-01Clinical Trial Update: Venetoclax in Addition to Sequential Conditioning With Fludarabine / Amsacrine / Ara-C (FLAMSA) + Treosulfan for Allogeneic Blood Stem Cell Transplantation in Patients With MDS, CMML or sAML [Phase 1, Phase 2]
A Phase 1/2 clinical trial assessing adding venetoclax to FLAMSA/treosulfan conditioning for allogeneic stem cell transplantation in patient…
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CLINICAL_TRIALS research · 2024-05-01Clinical Trial Update: Study of VA Combined With HAAG Regimen in Newly Diagnosed Intermediate and High-risk AML Patients [Phase 2]
This update describes a Phase 2 clinical trial evaluating the combination of VA with the HAAG regimen in adults with newly diagnosed interme…
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CLINICAL_TRIALS research · 2024-04-29Clinical Trial Update: A Study of AK117 in Combination With Azactidine Plus Venetoclax in Patients With Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating AK117 in combination with azacitidine and venetoclax in acute myeloid leukemia. The study is not yet rec…
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CLINICAL_TRIALS withdrawal · 2024-04-29Clinical Trial Update: High-Dose Post-Transplant Cyclophosphamide, Bortezomib, and Sitagliptin for the Prevention of GVHD [Phase 1, Phase 2]
The trial update indicates that the Phase 1/2 study of high-dose post-transplant cyclophosphamide, bortezomib, and sitagliptin for preventio…
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: Study of KHK2823 in Patients With Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) [Phase 1]
Phase 1 study of KHK2823 in Acute myeloid leukemia and myelodysplastic syndrome was terminated.
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CLINICAL_TRIALS research · 2024-04-29Clinical Trial Update: Role of Antifungal Prophylaxis in Elderly Patients With Acute Myeloid Leukemia During Consolidation Therapy
A clinical trial conducted by University of Rome Tor Vergata is evaluating antifungal prophylaxis to prevent invasive aspergillosis in elder…
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CLINICAL_TRIALS research · 2024-04-26Clinical Trial Update: Efficacy and Safety of MTBF Conditioning Regimen for Salvageable Allo-HSCT in the Treatment of R/R AML [NA]
This document reports on a clinical trial evaluating the MTBF conditioning regimen for salvageable allogeneic hematopoietic stem cell transp…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Study of Azacitidine，Venetoclax，and Flumatinib in Newly Diagnosed Ph-positive Acute Leukemia and CML-AP/BP Patients [Phase 2]
A Phase 2 study evaluating azacitidine, venetoclax, and flumatinib in newly diagnosed Ph-positive acute leukemia and CML-AP/BP; the trial ha…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Study of KW-2449 in Acute Myelogenous Leukemia (AML) (Protocol Number: 2449-US-002) [Phase 1]
An early-phase study evaluating KW-2449 in patients with acute myeloid leukemia reports on safety, tolerability, and pharmacokinetic/pharmac…
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CLINICAL_TRIALS trial_result · 2024-04-22Clinical Trial Update: Pilot Study of Pembrolizumab Treatment for Disease Relapse After Allogeneic Stem Cell Transplantation [EARLY_Phase 1]
A phase 1 pilot trial evaluating pembrolizumab for relapse after allogeneic stem cell transplantation in patients with classical Hodgkin lym…
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CLINICAL_TRIALS trial_result · 2024-04-19Clinical Trial Update: Family-mismatched/Haploidentical Donors Versus Matched Unrelated Donors [Phase 2, Phase 3]
Phase 2/3 trial comparing family-mismatched/haploidentical donors to matched unrelated donors in acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2024-04-18Clinical Trial Update: Phase II Study of the Combination of Mitoxantrone, Etoposide and Gemtuzumab Ozogamicin (MEGO) for Patients With Acute Myeloid Leukemia Refractory to Initial Standard Induction Therapy [Phase 2]
Phase II trial evaluating the MEGO combination (mitoxantrone, etoposide, gemtuzumab ozogamicin) in acute myeloid leukemia patients refractor…