Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-08-05Clinical Trial Update: Safety and Efficacy of Venetoclax, Cytarabine and Metformin (VenCM) for Relapsed-Refractory and Induction-Ineligible Acute Myeloid Leukemia [Phase 2]
A Phase 2 clinical trial evaluating the safety and efficacy of venetoclax, cytarabine, and metformin in relapsed/refractory or induction-ine…
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CLINICAL_TRIALS research · 2024-08-05Clinical Trial Update: VA Combined With PD-1 Inhibitor for the Treatment of Relapsed and Refractory AML and High-risk MDS [Phase 2]
A Phase 2 clinical trial is evaluating the combination of a VA agent with a PD-1 inhibitor for relapsed or refractory acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: Effect of Food on Blood Levels of ASTX727 [Phase 1]
Phase 1 trial evaluating the impact of food on plasma levels of ASTX727 (decitabine/cedazuridine) in patients with myelodysplastic syndromes…
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: Clinical Trial Protocol for the Combined Use of VAG in the Treatment of ND-AML [NA]
This document outlines a clinical trial protocol for the combined use of VAG in newly diagnosed acute myeloid leukemia and indicates that re…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: Study to Assess the Safety of Escalating Doses of AT9283, in Patients With Leukemias [Phase 1, Phase 2]
An early-phase study of escalating doses of AT9283 for various leukemias has been terminated.
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: A Study of ASTX660 as a Single Agent and in Combination With ASTX727 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (AML) [Phase 1]
This Phase 1 study evaluating ASTX660 alone and in combination with ASTX727 in relapsed/refractory acute myeloid leukemia has been terminate…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: A Study of TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid Neoplasms [Phase 1]
The Phase 1 study of TAS1553 in subjects with relapsed or refractory acute myeloid leukemia and other myeloid neoplasms has been terminated.
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: Arsenic Trioxide With Cyclophosphamide in Patients With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 trial evaluated arsenic trioxide in combination with cyclophosphamide in patients with relapsed/refractory acute myeloid leukemia.…
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: Tagraxofusp in Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm or Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial results for Tagraxofusp in Blastic Plasmacytoid Dendritic Cell Neoplasm and Acute Myeloid Leukemia have been …
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CLINICAL_TRIALS research · 2024-08-01Clinical Trial Update: Sorafenib Relapase Prophylaxis After HCT With PTBCy Regimen [Phase 2]
Phase 2 clinical trial evaluating sorafenib as relapse prophylaxis after hematopoietic cell transplantation using the PTBCy regimen; the stu…
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CLINICAL_TRIALS research · 2024-08-01Clinical Trial Update: Phase IIa Study to Assess Safety and Efficacy in the Relapsed/Refractory Acute Myeloid Leukemia [Phase 2]
Phase IIa study sponsored by Changzhou Qianhong Bio-pharma Co., Ltd. evaluating safety and efficacy in relapsed/refractory acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: A Phase 1 Study of AMG 330 in Subjects With Myeloid Malignancies [Phase 1]
Phase 1 study of AMG 330 in adults with myeloid malignancies, including relapsed/refractory acute myeloid leukemia and MRD-positive AML, has…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Vitamin A and D Supplementation in Allogeneic HCT [Phase 2]
Phase 2 clinical trial in allogeneic hematopoietic cell transplantation is evaluating vitamin A and vitamin D supplementation, currently rec…
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CLINICAL_TRIALS trial_result · 2024-07-30Clinical Trial Update: Idarubicin Plus Cytarabine (IA) vs IA Plus Cladribine (IAC) as Induction Regimen to Treat Initially Diagnosed Acute Myeloid Leukemia (AML) [Phase 3]
A Phase 3 trial comparing idarubicin plus cytarabine (IA) versus IA plus cladribine (IAC) as induction therapy for newly diagnosed acute mye…
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CLINICAL_TRIALS trial_result · 2024-07-30Clinical Trial Update: A Study of Cusatuzumab Plus Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia Who Are Not Candidates for Intensive Chemotherapy [Phase 2]
Phase 2 study of Cusatuzumab plus Azacitidine in newly diagnosed acute myeloid leukemia patients who are not candidates for intensive chemot…
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CLINICAL_TRIALS research · 2024-07-29Clinical Trial Update: Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+) [Phase 1]
Phase 1 clinical trial evaluating the combination of iadademstat and gilteritinib in patients with relapsed/refractory acute myeloid leukemi…
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CLINICAL_TRIALS withdrawal · 2024-07-29Clinical Trial Update: Study to Determine the Efficacy of Uproleselan (GMI-1271) in Combination With Chemotherapy to Treat Relapsed/Refractory Acute Myeloid Leukemia [Phase 3]
Phase 3 trial evaluating uproleselan (GMI-1271) in combination with chemotherapy for relapsed/refractory acute myeloid leukemia has been ter…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: Up-front Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia Patients Aged 65-75 [Phase 2]
Phase 2 clinical trial evaluating upfront hematopoietic stem cell transplantation in adults aged 65-75 with acute myeloid leukemia has compl…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: Haploidentical Allogeneic Peripheral Blood Transplantation: Examining Checkpoint Immune Regulators' Expression [Phase 3]
Phase 3 trial evaluating haploidentical allogeneic peripheral blood transplantation with analysis of checkpoint immune regulator expression;…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: Azacitidine With or Without Nivolumab or Midostaurin, or Decitabine and Cytarabine Alone in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome [Phase 2, Phase 3]
This clinical trial update reports results from Phase 2 and Phase 3 studies evaluating azacitidine with or without nivolumab or midostaurin,…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: Results From a French Temporary Utilization Authorization of First-line Acute Myeloid Leukemia (AML) Patients Ineligible for Intensive Chemotherapy (IC), Treated With Venetoclax Azacitidine
The document reports results from a French temporary utilization authorization study of first-line acute myeloid leukemia patients ineligibl…
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CLINICAL_TRIALS research · 2024-07-22Clinical Trial Update: Intensive Conditioning withTHI/Bu/Flu/Ara-C in Allo-HSCT for Myeloid Malignancies With Extramedullary Involvement
This clinical trial is testing an intensive conditioning regimen consisting of Thiotepa, Busulfan, Fludarabine, and Cytarabine followed by a…
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CLINICAL_TRIALS research · 2024-07-22Clinical Trial Update: ELN 2022 in MENAFC ( Middle Eastern or North Coast of Africa ) Patients With Newly AML
ClinicalTrials.gov entry describing a trial of the ELN 2022 risk-stratification approach in patients with newly diagnosed acute myeloid leuk…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: Safety and Efficacy of Allogeneic NK Cell Infusions in Patients With Relapsed/Refractory AML and High Risk MDS [Phase 1]
Phase 1 trial assessing safety and potential efficacy of allogeneic NK cell infusions in adults with relapsed/refractory acute myeloid leuke…
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: Use of T-allo10 in Hematopoietic Stem Cell Transplantation (HSCT) for Blood Disorders [Phase 1]
Phase 1 trial update on T-allo10 for hematopoietic stem cell transplantation in various blood disorders; the NCT03198234 study sponsored by …