Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-07-17Clinical Trial Update: Tipifarnib in Subjects With Chronic Myelomonocytic Leukemia, Other MDS/MPN, and Acute Myeloid Leukemia [Phase 2]
This Phase 2 trial evaluated tipifarnib in patients with chronic myelomonocytic leukemia and other myelodysplastic/myeloproliferative neopla…
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Reduced-Intensity Conditioning (RIC) and Myeloablative Conditioning (MAC) for HSCT in AML/MDS [Phase 2]
Phase 2 clinical trial update comparing reduced-intensity conditioning and myeloablative conditioning for hematopoietic stem cell transplant…
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CLINICAL_TRIALS research · 2024-07-11Clinical Trial Update: Phase II Study of Sonrotoclax Combined With Chemotherapy in the Treatment of Newly Diagnosed Acute Myeloid Leukemia [Phase 2]
This document provides an update on a Phase II clinical trial evaluating Sonrotoclax in combination with chemotherapy for newly diagnosed ac…
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CLINICAL_TRIALS research · 2024-07-10Clinical Trial Update: Incidence of Neutropenic Enterocolitis Study in Acute Myeloid Leukemia Patients During Intensive Therapy
A clinical trial (NCT03450512) is investigating the incidence of neutropenic enterocolitis in patients with acute myeloid leukemia undergoin…
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CLINICAL_TRIALS trial_result · 2024-07-10Clinical Trial Update: Haploidentical Stem Cell Transplantation Using Post-Transplant Cyclophosphamide [Phase 2]
Phase 2 haploidentical stem cell transplantation trial using post-transplant cyclophosphamide was terminated.
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CLINICAL_TRIALS research · 2024-07-10Clinical Trial Update: Study of NEROFE, a Novel Hormone-Peptide in Adult Patients With Advanced MDS and AML [Phase 1]
Phase 1 clinical trial update for NEROFE, a novel hormone-peptide, in adults with advanced myelodysplastic syndrome and acute myeloid leukem…
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CLINICAL_TRIALS other · 2024-07-10Clinical Trial Update: MRD Response-adapted Allo-HSCT for Adverse-risk AML [NA]
MRD response-adapted allogeneic stem cell transplantation for adverse-risk acute myeloid leukemia is currently recruiting at Peking Universi…
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CLINICAL_TRIALS trial_result · 2024-07-08Clinical Trial Update: Drug-screening in AML at Relapse for Targeted Treatment [NA]
This document reports that the clinical trial NCT05732688 evaluating drug-screening at relapse for targeted treatment in acute myeloid leuke…
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: Development and Application of a Novel Digital Array PCR for Acute Myeloid Leukemia (AML)
The document reports on the development and potential application of a novel digital array PCR assay for detecting acute myeloid leukemia an…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia (AML) Following Initial Treatment [Phase 2]
Phase 2 clinical trial investigating a combination therapy for persistent low-level acute myeloid leukemia after initial treatment. The stud…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: IL-6: A Marker for AML Chemo Sensitivity
A clinical study is evaluating whether interleukin-6 levels can predict chemotherapy response in adults with acute myeloid leukemia; the tri…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Individualized Treatment of Pediatric R/R AML Based on Transcriptomic Profile and in Vitro Drug Sensitivity Test [NA]
This clinical trial aims to personalize treatment for children with relapsed/refractory acute myeloid leukemia using transcriptomic profilin…
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: Study of ASTX727 vs IV Decitabine in Participants With MDS, CMML, and AML [Phase 3]
Phase 3 study comparing ASTX727 (cedazuridine/decitabine) versus intravenous decitabine in myelodysplastic syndromes, chronic myelomonocytic…
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CLINICAL_TRIALS research · 2024-07-01Clinical Trial Update: DCs Vaccine Combined With Cytokine-induced Killer Cells in Patients With AML [Phase 1, Phase 2]
Phase 1/2 clinical trial updating recruitment for a combination therapy using dendritic cell vaccine and cytokine-induced killer cells in pa…
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CLINICAL_TRIALS withdrawal · 2024-06-28Clinical Trial Update: Managed Access Programs for PKC412, Midostaurin
This update indicates that Novartis' managed access programs for midostaurin (PKC412) are no longer available, impacting access for patients…
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CLINICAL_TRIALS research · 2024-06-27Clinical Trial Update: Venetoclax + Cytarabine Versus Idarubicin + Cytarabine : Efficacity Assessment as Post-remission Therapy to Elderly Patients With Acute Myeloid Leukemia in First Remission [Phase 2]
Phase 2 clinical trial evaluating venetoclax plus cytarabine as post-remission therapy versus idarubicin plus cytarabine in elderly patients…
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: BeFluBu vs FluBuRux Conditioning in Haploidentical HCT [Phase 2]
Phase 2 clinical trial comparing BeFluBu vs FluBuRux conditioning regimens in haploidentical stem cell transplantation is currently recruiti…
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Anti-Covid-19 Vaccine in Children With Acute Leukemia and Their Siblings [Phase 1, Phase 2]
Phase 1/2 clinical trial assessing an anti-COVID-19 vaccine in children with acute leukemia and their siblings; study completed.
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CLINICAL_TRIALS research · 2024-06-26Clinical Trial Update: Acute Myeloid Leukemia At Initial Diagnosis and/or Relapse in Children, Teenagers and Young Adults: Molecular Profiling, Multidrug Testing and MSC Interaction Studies
Clinical trial investigating Acute Myeloid Leukemia at initial diagnosis or relapse in children, teenagers and young adults, with focus on m…
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: A Study Investigating the Safety, Tolerability and Efficacy of ASP7517 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (AML) and Relapsed/Refractory Higher Risk Myelodysplastic Syndrome (MDS) [Phase 1, Phase 2]
The document reports the completion and posting of results for a Phase 1/2 study evaluating ASP7517 for safety, tolerability, and preliminar…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Phase I/II Study of Enhanced CD33 CAR T Cells in Subjects With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
This update reports a completed Phase 1/2 trial of enhanced CD33-targeted CAR T cells in relapsed or refractory acute myeloid leukemia.
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Relationship Between Serum N/OFQ and Acute Myeloid Cell Leukemia
Clinical trial investigating the relationship between serum N/OFQ and acute myeloid leukemia; the study is currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-06-20Clinical Trial Update: FLT3 Clonal Evolution in Patients With Acute Myeloid Leukemia
This document reports the completion of a clinical trial investigating FLT3 clonal evolution in patients with Acute Myeloid Leukemia. The sp…
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: ACHIEVE2 - Safety and Preliminary Efficacy of Intravenous TCB008 in Patients With Relapse or Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)/AML [Phase 1]
Clinical trial update for ACHIEVE2 reports safety and preliminary efficacy data for intravenous TCB008 in patients with relapse or refractor…
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CLINICAL_TRIALS withdrawal · 2024-06-14Clinical Trial Update: Adding Venetoclax to the High-dose Chemotherapy Regimen Prior to Mismatche Allogeneic Stem Cell Transplant [Phase 2]
A Phase 2 trial evaluating adding venetoclax to high-dose chemotherapy before a mismatched allogeneic stem cell transplant for acute myeloid…