Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: MGTA-145 + Plerixafor in the Mobilization of HSCs for Allogeneic Transplant in Hematologic Malignancies [Phase 2]
Phase 2 study evaluating MGTA-145 in combination with Plerixafor for mobilizing hematopoietic stem cells for allogeneic transplantation in h…
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CLINICAL_TRIALS research · 2024-08-28Clinical Trial Update: Immunotherapy With ex Vivo Expanded Haploidentical Natural Killer Cells for Children/Young Adults With AML [Phase 1, Phase 2]
Clinical trial update for immunotherapy using ex vivo expanded haploidentical natural killer cells in children and young adults with acute m…
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CLINICAL_TRIALS research · 2024-08-28Clinical Trial Update: Expanded Haploidentical Natural Killer Cells as Consolidation Strategy for Children/Young Adults With AML [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating expanded haploidentical natural killer cells as a consolidation therapy for children and young adults …
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CLINICAL_TRIALS research · 2024-08-26Clinical Trial Update: RIC Allo-HSCT vs. Venetoclax-Based Consolidation in Elderly AML Patients After First CR [Phase 4]
Phase 4 clinical trial comparing reduced-intensity conditioned allogeneic stem cell transplant against venetoclax-based consolidation in eld…
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Baricitinib at Children and Young Adults With Hemoblastosis [Phase 2, Phase 3]
Phase 2/Phase 3 trial evaluating a combination of post-transplant cyclophosphamide, abatacept, vedolizumab, and baricitinib to prevent graft…
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: Clinical Study of Induction Therapy Options Based on Molecular Subtyping and MRD in Children and Adolescents With AML [Phase 2]
A Phase 2 clinical trial in children and adolescents with acute myeloid leukemia evaluating induction therapy options based on molecular sub…
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: CHG Combined With Venetoclax and Azacytidine in Newly Diagnosed AML [Phase 2]
A Phase 2 clinical trial is evaluating CHG-based chemotherapy in combination with venetoclax and azacitidine for newly diagnosed acute myelo…
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: Study of CFI-400945 Fumarate in Patients With Relapsed or Refractory AML or MDS [Phase 1]
Phase 1 trial of CFI-400945 fumarate in relapsed or refractory acute myeloid leukemia and myelodysplastic syndromes has completed.
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation [Phase 2]
This notice describes a Phase 2 clinical trial evaluating avapritinib for relapsed or refractory pediatric core-binding factor acute myeloid…
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: SL-401 as Consolidation Therapy in Patients With Adverse Risk Acute Myeloid Leukemia in First Complete Remission [Phase 1, Phase 2]
Clinical trial update reports results for SL-401 as consolidation therapy in adverse-risk acute myeloid leukemia in first complete remission…
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CLINICAL_TRIALS trial_result · 2024-08-19Clinical Trial Update: Uproleselan With Pre-Transplant Conditioning in Hematopoietic Stem Cell Transplantation for AML [Phase 1]
Phase 1 trial of uproleselan with pre-transplant conditioning in hematopoietic stem cell transplantation for acute myeloid leukemia has been…
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CLINICAL_TRIALS research · 2024-08-19Clinical Trial Update: Hema-NeoTIL01 Cell Infusion Therapy in Relapsed/Refractory Acute Leukemia [EARLY_Phase 1]
This is an early Phase 1 trial update for Hema-NeoTIL01 cell infusion therapy in relapsed/refractory acute leukemia, including acute myeloid…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: A Study of Revumenib in Combination With Chemotherapy in Participants With R/R Acute Leukemia [Phase 1]
Phase 1 study evaluating revumenib in combination with chemotherapy for relapsed/refractory acute leukemias has completed.
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CLINICAL_TRIALS withdrawal · 2024-08-13Clinical Trial Update: Venetoclax-Navitoclax With Cladribine-based Salvage Therapy in Patients With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 trial evaluating venetoclax and navitoclax with cladribine-based salvage therapy for relapsed/refractory acute myeloid leukemia ha…
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CLINICAL_TRIALS research · 2024-08-13Clinical Trial Update: A Clinical Trial of TQB3455 Tablets in Patients With Hematological Malignancies [Phase 1]
Phase 1 clinical trial of TQB3455 tablets for hematological malignancies is currently recruiting in patients with acute myeloid leukemia and…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Psychological Intervention Mobile App for Patients With AML [NA]
A completed clinical trial evaluating a psychological intervention mobile app designed to support patients with acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2024-08-12Clinical Trial Update: Study of MEN1112 Intravenous Infusion in Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 study of MEN1112 intravenous infusion in relapsed or refractory acute myeloid leukemia was terminated; results have been posted.
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Individual Patient Compassionate Use of Crenolanib
Clinical trial update indicating that crenolanib is available for individual patient compassionate use in cancers with FLT3-ITD/FLT3-TKD mut…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Safety and Efficacy of NK520 to Treat Pediatric Relapsed/Refractory Acute Myeloid Leukemia [EARLY_Phase 1]
An early-phase clinical trial is evaluating the safety and potential efficacy of NK520 in pediatric patients with relapsed/refractory acute …
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Study to Improve OS in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus MMF Prophylaxis of GvHD in Allografted Patients in First CR [Phase 2, Phase 3]
A multi-arm Phase 2/Phase 3 study in adults with acute myeloid leukemia compares daunorubicin versus high-dose idarubicin induction, high-do…
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Safety and Efficacy of NK520 to Treat Relapsed/Refractory Acute Myeloid Leukemia [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating the safety and potential efficacy of NK520 for relapsed/refractory acute myeloid leukemia, curren…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: A Study to Evaluate Lanraplenib (LANRA) in Combination With Gilteritinib in Participants With FLT3-mutated Relapsed or Refractory Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
This clinical trial update reports results from a Phase 1/2 study evaluating lanraplenib in combination with gilteritinib in FLT3-mutated re…
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CLINICAL_TRIALS withdrawal · 2024-08-07Clinical Trial Update: ELU001 in Pediatric Subjects Who Have Relapsed and/or Refractory CBFA2T3-GLIS2-positive AML [Phase 1]
A Phase 1 trial of ELU001 for CBFA2T3-GLIS2-positive pediatric acute myeloid leukemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Haploidentical Donor vs mMUD in Hematological Malignancies [Phase 2, Phase 3]
A Phase 2/3 clinical trial comparing haploidentical donor transplantation to matched unrelated donor transplantation in hematologic malignan…
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: FLT PET/CT in Measuring Response in Patients With Previously Untreated Acute Myeloid Leukemia [Phase 2]
This Phase 2 trial update reports results on using FLT PET/CT to measure response in patients with previously untreated acute myeloid leukem…