Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: CD123-CD16-NK Cells Immunotherapy for AML [Phase 1]
Phase 1 clinical trial evaluating CD123-CD16-NK cell immunotherapy for Acute Myeloid Leukemia is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: Tamibarotene Plus Venetoclax/Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 trial evaluating tamibarotene in combination with venetoclax and azacitidine in newly diagnosed acute myeloid leukemia has been term…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Study of Tretinoin Capsules in Combination With Azacitidine and Venetoclax in Treatment Naïve Participants With Acute Myeloid Leukemia [NA]
A planned clinical trial to test the combination of tretinoin capsules with azacitidine and venetoclax in adults with treatment-naïve acute …
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Dose-escalation Study of D-CMG Regimen for the Treatment of Elderly Newly Diagnosed AML Patients [Phase 1]
This clinical trial update announces a phase 1 dose-escalation study evaluating the D-CMG regimen for elderly patients with newly diagnosed …
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Chiglitazar Sodium Combined With Venetoclax and Azacitidine (CVA) for the Treatment of R/R AML [Phase 1]
Phase 1 clinical trial evaluating chiglitazar sodium combined with venetoclax and azacitidine (CVA) for relapsed/refractory acute myeloid le…
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: APR-246 in Combination With Venetoclax and Azacitidine in TP53-Mutant Myeloid Malignancies [Phase 1]
Phase 1 study evaluating APR-246 in combination with venetoclax and azacitidine for TP53-mutant myeloid malignancies has completed and poste…
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: IDH1/2 Mutational Analysis in AML Patients: Diagnosis and Follow-up
This update reports on a completed study examining IDH1/2 mutational analysis in patients with Acute Myeloid Leukemia to aid diagnosis and f…
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: Cardioprotection in AML [Phase 2]
This clinical trial update describes a Phase 2 study on cardioprotection in acute myeloid leukemia that is currently recruiting. The sponsor…
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CLINICAL_TRIALS trial_result · 2025-02-20Clinical Trial Update: Acute Myeloid Leukemia Treated With With NETrin Abs in Combination With [AZACITIDINE + VENETOCLAX] [Phase 1, Phase 2]
A Phase 1/2 trial evaluating NETrin Abs in combination with azacitidine and venetoclax for refractory acute myeloid leukemia has been termin…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Veneclax, Chidaniline Combined With Azacitidine Followed by Decitabine + MAG Regimen in the Treatment of Elderly Untreated AML [Phase 2]
Phase 2 trial update for elderly patients with untreated acute myeloid leukemia evaluating Veneclax and Chidaniline with Azacitidine, follow…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: VCA Regimen Followed by D-MAG Regimen on the Treatment of Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 clinical trial evaluating a sequence of the VCA regimen followed by the D-MAG regimen for elderly patients with newly diagnosed acut…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Randomized Study of Conditioning of Fludarabine Combined With Single or Dual Alkylating Agents in Myeloid Malignancies [Phase 3]
A Phase 3 randomized trial evaluating conditioning with fludarabine plus single versus dual alkylating agents in myeloid malignancies (acute…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Chemotherapy CLAGE-Ven Sequential With Reduced Intensity Conditioning for Refractory Acute Myelodi Leukemia [Phase 2]
Phase 2 clinical trial evaluating sequential chemotherapy CLAGE-Ven with reduced-intensity conditioning for refractory acute myeloid leukemi…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: A Study of Midostaurin Efficacy and Safety in Newly Diagnosed Patients With FLT3-mutated AML [Phase 2]
A Phase 2 trial assessing the efficacy and safety of midostaurin in newly diagnosed FLT3-mutated acute myeloid leukemia has completed enroll…
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CLINICAL_TRIALS research · 2025-02-10Clinical Trial Update: Reduced Intensity Conditioning Regimens for Acute Myeloid Leukemia and Myelodysplastic Syndrome [Phase 3]
A Phase 3 clinical trial update evaluating reduced-intensity conditioning regimens for patients with acute myeloid leukemia or myelodysplast…
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: A Telehealth Advance Care Planning Intervention for Older Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome [NA]
This clinical trial update reports results for a telehealth advance care planning intervention targeting older patients with Acute Myeloid L…
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: HVA vs IA/DA or VA in the Treatment of ND HR-AML [Phase 3]
A Phase 3 clinical trial comparing HVA regimens against IA/DA or VA regimens for newly diagnosed high-risk acute myeloid leukemia is current…
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CLINICAL_TRIALS trial_result · 2025-02-05Clinical Trial Update: Study of Magrolimab in Combination With Azacitidine Versus Physician's Choice of Venetoclax in Combination With Azacitidine or Intensive Chemotherapy in Patients With TP53 Mutant Acute Myeloid Leukemia That Have Not Been Treated [Phase 3]
Phase 3 study of magrolimab in combination with azacitidine in TP53-mutant acute myeloid leukemia was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Study of Allogeneic Double Negative T Cells (DNT-UHN-1) in Patients With High Risk Acute Myeloid Leukemia [Phase 1]
Phase 1 trial assessing allogeneic double negative T cells (DNT-UHN-1) in high-risk acute myeloid leukemia has completed.
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CLINICAL_TRIALS research · 2025-01-31Clinical Trial Update: Interferon-alpha As Maintenance Therapy for Favorable-risk Acute Myeloid Leukemia [Phase 3]
This clinical trial update describes a Phase 3 study evaluating interferon-alpha as maintenance therapy in favorable-risk acute myeloid leuk…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Tagraxofusp in Patients With CD123+ or With BPDCN-IPh-like Acute Myeloid Leukemia [Phase 2]
Phase 2 study of Tagraxofusp in patients with CD123+ or BPDCN-like acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS research · 2025-01-30Clinical Trial Update: Molecular Characterization of Patients With Acute Myeloid Leukemia and the Impact of Clonal Evolution in the Response to Therapeutic Treatments
This clinical trial update outlines the molecular characterization of patients with acute myeloid leukemia and investigates how clonal evolu…
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CLINICAL_TRIALS withdrawal · 2025-01-29Clinical Trial Update: Correlation of Serum Gasdermin-D and NLRP-3 Inflammasome Levels With GVHD Biomarkers and Endothelial Damage Markers in Graft-Versus-Host Disease
A clinical trial investigating correlations between serum biomarkers and GVHD-related endothelial damage has been withdrawn. The study recor…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Relation of C-reactive Protein/ Albumin Ratio and Coagulation Profile in Acute Myeloid Leukemia Patients
Assiut University is conducting a clinical study to examine the relationship between the C-reactive protein/albumin ratio and coagulation pa…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: GITMO AML/MDS-Relapse Registry Study
The GITMO AML/MDS-Relapse Registry Study has completed.