Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Epidemiology of Infection in Acute Myeloid Leukemia (AML)
This clinical trial update examines the epidemiology of infections in patients with acute myeloid leukemia, and the study is not yet recruit…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Phase I Study of GNKG168 in Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia [Phase 1]
This clinical trial update summarizes Phase I results for GNKG168 in relapsed acute lymphoblastic leukemia and relapsed acute myeloid leukem…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Safety and Clinical Activity of KT-253 in Adult Patients with High Grade Myeloid Malignancies, Acute Lymphocytic Leukemia, Lymphoma, Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating safety and preliminary activity of KT-253 in adults with high-grade myeloid malignancies, acute lymphoblas…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: BI 836858 Dose Escalation in Patients With Refractory or Relapsed Acute Myeloid Leukemia and in Patients With AML in Complete Remission With High Risk to Relapse [Phase 1]
Phase 1 dose-escalation trial of BI 836858 in adults with refractory or relapsed acute myeloid leukemia and in AML in complete remission wit…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Trial of LAVA-051 in Patients with Relapsed/refractory CLL, MM, or AML [Phase 1]
The Phase 1 trial of LAVA-051 in relapsed/refractory Chronic Lymphocytic Leukemia, Multiple Myeloma, or Acute Myeloid Leukemia has been term…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer [NA]
This update reports the completion of a clinical trial evaluating health care coach support to reduce acute care use and costs in cancer pat…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: SGI-110 in Participants With Myelodysplastic Syndromes (MDS) or Acute Myelogenous Leukemia (AML) [Phase 1, Phase 2]
Clinical trial update reporting completion and posted results for SGI-110 (guadecitabine) in patients with myelodysplastic syndromes, chroni…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Clinical Study on the Safety and Efficacy of Autologous CD84 Chimeric Antigen Receptor T-Cell Therapy for Adult Relapsed/Refractory Acute Myeloid Leukemia. [EARLY_Phase 1]
An early-phase study is evaluating autologous CD84 CAR-T cell therapy for adults with relapsed or refractory acute myeloid leukemia; the tri…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Expectations of Patients in Palliative Situation
A clinical trial in acute myeloid leukemia at University Hospital Montpellier is examining patients' expectations in a palliative care setti…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: First-in-human Study Aiming to Characterize the Safety, Tolerability, Pharmacokinetic and Preliminary Signs of Activity of ABD-3001 in Refractory or Relapsed AML and High Risk MDS Adult Patients [Phase 1, Phase 2]
First-in-human Phase 1/2 study of ABD-3001 to evaluate safety, tolerability, pharmacokinetics, and preliminary activity in adults with refra…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Avapritinib Combined With Azacitidine and Venetoclax in the Treatment of Relapsed AML After Allo-HSCT [Phase 2]
Phase 2 clinical trial evaluating the combination of avapritinib with azacitidine and venetoclax for relapsed acute myeloid leukemia after a…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: NK Cell Infusion for Remission Consolidation in AML: A Phase II Trial [Phase 2]
A Phase II study evaluating natural killer (NK) cell infusion as remission-consolidation therapy for acute myeloid leukemia; the trial is cu…
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CLINICAL_TRIALS research · 2025-01-17Clinical Trial Update: Azacitidine Combined with Donor Lymphocyte Infusion for Acute Myeloid Leukemia Post-transplant Relapse Prevention. [Phase 2]
A Phase 2 clinical trial evaluating azacitidine in combination with donor lymphocyte infusion to prevent relapse of acute myeloid leukemia a…
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FDA approval · 2025-01-16FDA Approved: IDHIFA — Supplemental Application (Celgene Corporation)
FDA approved a supplemental application for IDHIFA (enasidenib mesylate) submitted by Celgene Corporation.
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: Accelerated Dose Schedule of Cytarabine Consolidation Therapy for Older Patients With Acute Myeloid Leukemia (AML) in Complete Remission [Phase 2]
A Phase 2 study evaluating an accelerated cytarabine consolidation schedule for older patients with acute myeloid leukemia in complete remis…
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CLINICAL_TRIALS research · 2025-01-16Clinical Trial Update: Intermediate-dose HAD Regimen for CEBPA Double-mutated AML [NA]
The document notes an ongoing clinical trial in China evaluating an intermediate-dose HAD regimen for CEBPA double-mutated acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2025-01-14Clinical Trial Update: A Study of ASP2215 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase 3 (FLT3) Mutation [Phase 3]
Phase 3 trial comparing ASP2215 (gilteritinib) to salvage chemotherapy in relapsed or refractory acute myeloid leukemia with FLT3 mutation. …
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CLINICAL_TRIALS trial_result · 2025-01-14Clinical Trial Update: A Study of Siremadlin Alone and in Combination With Donor Lymphocyte Infusion in Acute Myeloid Leukemia Post-allogeneic Stem Cell Transplant [Phase 1, Phase 2]
Clinical trial evaluating siremadlin alone and in combination with donor lymphocyte infusion for acute myeloid leukemia after allogeneic ste…
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 trial evaluating the addition of ivosidenib to chemotherapy for IDH1-mutant relapsed or refractory acute myeloid leukemia, including…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Selinexor Combined With Venetoclax Maintenance Therapy After Allo-HSCT [Phase 2]
Phase 2 clinical trial update evaluating the combination of selinexor and venetoclax as maintenance therapy after allogeneic hematopoietic s…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Avapritinib Maintenance for AML With KIT Mutations [Phase 2]
Phase 2 trial evaluating maintenance avapritinib in adults with acute myeloid leukemia harboring KIT mutations; the study status is not yet …
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Liquid Micro-biopsy: a Novel Approach to Study Tumor Microenvironment From the Peripheral Blood
A clinical trial is evaluating a liquid micro-biopsy method from peripheral blood to study the tumor microenvironment. The study targets pat…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: CLAG+VEN vs CLAG in the Treatment of Relapsed/Refractory AML [Phase 4]
This Phase 4 trial compares CLAG+venetoclax versus CLAG for relapsed/refractory acute myeloid leukemia and is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-01-07Clinical Trial Update: Ipilimumab and Decitabine in Treating Patients With Relapsed or Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial update on the combination of ipilimumab and decitabine in patients with relapsed or refractory myelodysplastic syndro…
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: A Clinical Study to Explore the Safety and Efficacy of CD33 CAR-T Cell in Relapsed/Refractory Acute Myeloid Leukemia [EARLY_Phase 1]
An early-phase study evaluating the safety and efficacy of CD33-directed CAR-T cells in relapsed or refractory acute myeloid leukemia. The t…