Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Collecting and Storing Tissue From Young Patients With Cancer
A completed clinical trial update from the Children’s Oncology Group describing the collection and storage of tissue from pediatric cancer p…
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CLINICAL_TRIALS withdrawal · 2025-05-01Clinical Trial Update: Dasatinib Combined With Chemotherapy in Relapsed t(8;21) Acute Myeloid Leukemia With KIT D816 Mutation [Phase 1]
Phase 1 trial evaluating dasatinib in combination with chemotherapy for relapsed acute myeloid leukemia with t(8;21) translocation and KIT D…
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: CLAG-GO for Patients With Persistent, Relapsed or Refractory AML [Phase 2]
Phase 2 clinical trial update for the CLAG-GO regimen in adults with persistent, relapsed, or refractory acute myeloid leukemia, currently r…
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CLINICAL_TRIALS trial_result · 2025-04-30Clinical Trial Update: Studying Malnutrition And Sarcopenia In Older Adults With Acute Myeloid Leukemia
A clinical trial investigating malnutrition and sarcopenia in older adults with acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: IFN-γ to Treat Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) That Has Relapsed After Allogeneic Hematopoietic Stem Cell Transplantation [EARLY_Phase 1]
A Phase 1 trial evaluating interferon-gamma (IFN-γ) for relapsed myelodysplastic syndrome and acute myeloid leukemia after allogeneic stem c…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia [EARLY_Phase 1]
A Phase 1 trial evaluating a combination of sirolimus, idarubicin, and cytarabine in adults with newly diagnosed acute myeloid leukemia has …
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: MEN1703 (SEL24) in Participants With Acute Myeloid Leukemia [Phase 1, Phase 2]
This clinical trial update reports completed Phase 1/2 results for MEN1703 (SEL24) in participants with Acute Myeloid Leukemia. Results were…
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CLINICAL_TRIALS withdrawal · 2025-04-29Clinical Trial Update: Mobile Intervention to Improve Adherence of Oral Anti-cancer Medications Among Acute Myeloid Leukemia Patients, the txt4AML Study [NA]
A clinical trial testing a mobile intervention to improve adherence to oral anti-cancer medications in acute myeloid leukemia has been withd…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: Study of Oral Venetoclax Tablets to Evaluate Adverse Events and Change in Disease Activity in Participants of Any Age With Acute Myeloid Leukemia
This clinical trial update summarizes the study of oral venetoclax in participants with acute myeloid leukemia, focusing on adverse events a…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: Biomarkers in Patients With Anemia-Induced Thrombocytopenic Bleeding [NA]
This clinical trial update notes ongoing recruitment for a study examining biomarkers in patients with anemia-induced thrombocytopenic bleed…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Total Body Irradiation and Cladribine Before Allogeneic Hematopoietic Cell Transplantation in Patients With AML (Acute Myeloid Leukemia) and Myelodysplastic Syndromes [Phase 2]
A Phase 2 clinical trial is evaluating total body irradiation and cladribine as conditioning before allogeneic hematopoietic cell transplant…
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: Study of REM-422 in Patients With AML or Higher Risk MDS [Phase 1]
Remix Therapeutics is conducting a Phase 1 study of REM-422 in patients with myelodysplastic syndromes and acute myeloid leukemia, including…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Azacitidine, Venetoclax, and Trametinib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Higher-Risk Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating a three-drug combination of azacitidine, venetoclax, and trametinib for relapsed or refractory acute myeloid leukem…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Tocilizumab for the Prevention of Graft Versus Host Disease After Cord Blood Transplantation [Phase 2]
Phase 2 trial evaluating tocilizumab to prevent graft-versus-host disease after cord blood transplantation has been completed.
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: Matched Unrelated vs. Haploidentical Donor for Allogeneic Stem Cell Transplantation in Patients With Acute Leukemia [Phase 2]
This entry describes a Phase 2 clinical trial evaluating matched unrelated donor versus haploidentical donor approaches for allogeneic stem …
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: A Study to Asses Effectiveness and Treatment Management of Oral Venetoclax Tablets + Subcutaneously Injected Azacitidine in Adult Participants Ineligible for Intensive Chemotherapy With de Novo Acute Myeloid Leukemia (AML) in Italy
An ongoing Italy-based study evaluating oral venetoclax plus subcutaneous azacitidine in adults with de novo acute myeloid leukemia who are …
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CLINICAL_TRIALS withdrawal · 2025-04-22Clinical Trial Update: Trial of Cladribine and Low-Dose Cytarabine (LoDAC) Alternating With Decitabine vs. Hypomethylating Agents (HMA) Plus Venetoclax as Frontline Therapy for AML or High-Grade MDS in Patients Unfit for Intensive Induction [Phase 2]
Phase 2 frontline trial evaluating cladribine/low-dose cytarabine alternating with decitabine versus hypomethylating agents plus venetoclax …
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial [Phase 2]
Phase 2 trial evaluating fecal microbiota transplantation before allogeneic stem cell transplant; recruitment is ongoing across multiple hem…
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Phase I Clinical Study: BG1805 Injection in the Treatment of Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
This entry notes an ongoing Phase I/II clinical trial, currently recruiting, evaluating BG1805 injection for relapsed or refractory acute my…
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Cusatuzumab in Combination With Background Therapy for the Treatment of Participants With Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial evaluating cusatuzumab in combination with background therapy for acute myeloid leukemia. The study is currently acti…
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT) [Phase 1]
Phase 1 clinical trial assessing a preventive therapy to reduce graft-versus-host disease in participants with hematologic malignancies unde…
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CLINICAL_TRIALS research · 2025-04-13Clinical Trial Update: A Phase Ⅰb/Ⅱ Clinical Study of Clifutinib Besylate Combined With Chemotherapy in the Treatment of Newly Diagnosed AML [Phase 1, Phase 2]
A Phase Ⅰb/Ⅱ clinical trial evaluating clifutinib besylate in combination with chemotherapy for newly diagnosed acute myeloid leukemia is cu…
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CLINICAL_TRIALS research · 2025-04-13Clinical Trial Update: Safety and Efficacy of RVU120 Combined With Venetoclax for Treatment of Relapsed/Refractory AML [Phase 2]
Ongoing Phase 2 study evaluating the safety and efficacy of RVU120 in combination with venetoclax for relapsed/refractory acute myeloid leuk…
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: Phase I/II Trial of S65487 Plus Azacitidine in Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase I/II clinical trial evaluating S65487 plus azacitidine for Acute Myeloid Leukemia; the study is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation [Phase 1]
Phase 1 safety study of IDH1/IDH2 inhibitors AG-120 (ivosidenib) or AG-221 (enasidenib) combined with induction and consolidation therapy fo…