Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Molecular Genetics Guide the Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation [Phase 2, Phase 3]
Phase 2/Phase 3 clinical trial investigating molecular genetics-guided maintenance therapy after allogeneic hematopoietic stem cell transpla…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Pharmacoscopy-guided Clinical Standard-of-care in r/r AML [Phase 2]
Phase 2 trial evaluating pharmacoscopy-guided standard-of-care for relapsed/refractory acute myeloid leukemia is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: STAT Inhibitor OPB-111077, Decitabine and Venetoclax in Treating Patients With Acute Myeloid Leukemia That Is Refractory, Relapsed or Newly Diagnosed and Ineligible for Intensive Chemotherapy [Phase 1]
This Phase 1 trial evaluated the combination of the STAT inhibitor OPB-111077 with Decitabine and Venetoclax in patients with Acute Myeloid …
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Palliative Care Oncology in Patients With Relapsed, Refractory, and High-Risk Leukemias or MDS [Phase 2]
This clinical trial update describes a Phase 2 study evaluating palliative care oncology in adults with relapsed, refractory, or high-risk a…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: ASTX727 and Donor Lymphocyte Infusions After Allogenic Stem Cell Transplantation in Very High Risk MDS or AML Patients [Phase 2]
Phase 2 trial evaluating ASTX727 with donor lymphocyte infusions after allogeneic stem cell transplantation in very high risk myelodysplasti…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Phase 1 Study of Allo-RevCAR01-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies [Phase 1]
Phase 1 study evaluating Allo-RevCAR01-T-CD123 in CD123-positive hematologic malignancies, including relapsed or refractory acute myeloid le…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: IDH Targeted/Non- Targeted vs Non-targeted/IDH-targeted Approaches in the Treatment of Newly Diagnosed IDH Mutated AML Patients Not Candidates for Intensive Induction Therapy (I- DATA Study) [Phase 2]
A Phase 2 clinical trial (I- DATA Study) compares IDH-targeted versus non-targeted treatment approaches in newly diagnosed IDH-mutated acute…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Daunorubicin + Cytarabine + Venetoclax in de Novo AML [NA]
This entry notes a clinical trial evaluating daunorubicin, cytarabine, and venetoclax in newly diagnosed acute myeloid leukemia, with enroll…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Analysis of the Immunobiology of Acute Myeloid Leukemia Relapses After Allogeneic Hematopoietic Stem Cell Transplant (HSCT) for the Generation of Guidelines and Personalized Therapeutic Pathways
This clinical trial update analyzes the immunobiology of acute myeloid leukemia relapses after allogeneic hematopoietic stem cell transplant…
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: Augmentation of the Graft vs. Leukemia Effect Via Checkpoint Blockade With Pembrolizumab [Phase 1]
Phase 1 study evaluating pembrolizumab to augment graft-versus-leukemia effect in patients with myelodysplastic syndromes and acute myeloid …
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: APVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AML [Phase 1]
APVO436 is being studied in a Phase 1b/2 trial for newly diagnosed acute myeloid leukemia, with recruitment ongoing for the Phase 1 portion.
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: Conditioning Regimen in Elderly AML Patients Receiving Haplo-HSCT. [NA]
This clinical trial update discusses a conditioning regimen for elderly patients with acute myeloid leukemia undergoing haploidentical hemat…
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: Decoding the Inflammasome Influence on Treatment Response in Acute Myeloid Leukemia
This clinical trial update describes a study investigating how inflammasome signaling influences treatment response in Acute Myeloid Leukemi…
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: LY3214996 in Patients With AML Who Are Not Candidates for Standard Therapy [Phase 1]
A Phase 1 clinical trial update for LY3214996 in patients with acute myeloid leukemia who are not candidates for standard therapy, with the …
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: XmAb18968 (CD3-CD38) in Relapsed or Refractory Acute Leukemia and T Cell Lymphoblastic Leukemia [Phase 1]
Phase 1 trial of XmAb18968 (CD3-CD38) in relapsed or refractory acute myeloid leukemia and T-cell lymphoblastic leukemia/lymphoma has been t…
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: Safety and Efficacy of RVU120 for Treatment of Relapsed/Refractory AML [Phase 2]
Clinical trial update on RVU120 for relapsed/refractory acute myeloid leukemia in a Phase 2 study. The trial is currently active but not rec…
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EMA approval · 2025-05-07EMA Authorised: Daurismo (Glasdegib maleate) — Pfizer Europe MA EEIG
The European Medicines Agency authorized Daurismo (glasdegib) from Pfizer Europe MA EEIG for acute myeloid leukemia, with orphan medicine de…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Venetoclax and Azacitidine for Non-Elderly Adult Patients With Acute Myeloid Leukemia [Phase 2]
A Phase 2 trial assessing venetoclax in combination with azacitidine for non-elderly adults with acute myeloid leukemia; the study is curren…
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CLINICAL_TRIALS trial_result · 2025-05-06Clinical Trial Update: Tagraxofusp-erzs, an IL-3 Diphtheria Fusion Protein, in Combination With Gemtuzumab Ozogamicin in Patients With Relapsed/Refractory AML [Phase 1]
Phase 1 trial update evaluating Tagraxofusp-erzs in combination with gemtuzumab ozogamicin for relapsed/refractory acute myeloid leukemia.
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Registry of Myelodysplastic Syndromes and Therapy-related Acute Myeloid Leukemia
A new clinical trial registry entry for patients with myelodysplastic syndromes and acute myeloid leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Refining the Role of Mid-induction Bone Marrow Biopsy in Acute Myeloid Leukemia: A Pilot Study
A pilot study at University of Alabama at Birmingham is investigating the role of mid-induction bone marrow biopsy in Acute Myeloid Leukemia…
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CLINICAL_TRIALS trial_result · 2025-05-04Clinical Trial Update: Study of the Safety and Efficacy of Gemtuzumab Ozogamicin (GO) and Venetoclax in Patients With Relapsed or Refractory CD33+ Acute Myeloid Leukemia:Big Ten Cancer Research Consortium BTCRC-AML17-113 [Phase 1]
Phase 1 study evaluating the safety and preliminary efficacy of combining Gemtuzumab ozogamicin with Venetoclax in adults with relapsed or r…
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Donor-Derived Ex-Vivo Expanded Natural Killer Cell Infusions in Children and Young Adults With High Risk Acute Myeloid Leukemia Receiving Myeloablative HLA-Haploidentical Hematopoietic Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating donor-derived ex-vivo expanded natural killer cell infusions in pediatric and young adult patients with hi…
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: KIR Favorable Mismatched Haplo Transplant and KIR Polymorphism in ALL/AML/MDS Allo-HCT Children [Phase 2]
This clinical trial update describes a Phase 2 study evaluating KIR-favorable mismatched haploidentical transplantation and KIR polymorphism…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies [Phase 1]
Phase 1 study update for Orca-T in recipients undergoing allogeneic transplantation for hematologic malignancies; the trial is currently act…