Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: An Open-label Phase 3b Study of Ivosidenib in Combination With Azacitidine in Adult Patients Newly Diagnosed With IDH1m Acute Myeloid Leukemia (AML) Ineligible for Intensive Induction Chemotherapy. [Phase 3]
Open-label Phase 3b trial of ivosidenib plus azacitidine in IDH1-mutant acute myeloid leukemia patients ineligible for intensive chemotherap…
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CLINICAL_TRIALS trial_result · 2025-04-10Clinical Trial Update: Dexamethasone in Refractory or First Relapsed Acute Myeloid Leukemia [Phase 3]
Phase 3 trial evaluating dexamethasone for relapsed or refractory acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Single Cell Acute Leukemia Analysis [NA]
This clinical trial update describes a study on single-cell analysis in acute myeloid leukemia, which is not yet recruiting.
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: A Study of HYML-122 and Cytarabine in Patients With FLT3 Positive Relapsed or Refractory Acute Myeloid Leukemia (AML) [Phase 2]
A Phase 2 clinical trial evaluating HYML-122 plus Cytarabine in FLT3-positive relapsed or refractory AML; currently recruiting.
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Breath Analysis for the Detection of Invasive Fungal Infections
This clinical trial update describes a breath analysis approach being studied to detect invasive fungal infections in patients with leukemia…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Micro-transplantation in Elderly Patients With Acute Myeloid Leukemia [NA]
This clinical trial entry notes a study evaluating micro-transplantation in elderly patients with acute myeloid leukemia, currently in the r…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: HEC73543 Versus Salvage Chemotherapy in R/R FLT3-ITD AML [Phase 3]
Phase 3 trial evaluating HEC73543 versus salvage chemotherapy in relapsed/refractory FLT3-ITD acute myeloid leukemia is currently recruiting…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Combination Salvage Therapy With Venetoclax and Decitabine in Relapsed/Refractory AML [Phase 2]
Phase 2 clinical trial evaluating salvage therapy with venetoclax and decitabine for relapsed/refractory acute myeloid leukemia. The study a…
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CLINICAL_TRIALS trial_result · 2025-04-07Clinical Trial Update: Investigating Integrative Therapies for Symptom Management in Adults With Acute Leukemia [NA]
A clinical trial evaluating integrative therapies for symptom management in adults with acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Study of Itacitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation [Phase 1]
Phase 1 study evaluating itacitinib for prophylaxis of graft-versus-host disease and cytokine release syndrome after T-cell replete haploide…
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Donor Stem Cell Transplantation Using α/β+ T-lymphocyte Depleted Grafts From HLA Mismatched Donors [Phase 2]
A Phase 2 trial evaluating α/β+-T lymphocyte-depleted donor grafts from HLA-mismatched donors in multiple hematologic malignancies was termi…
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: MCLA-117 in Acute Myelogenous Leukemia [Phase 1]
A Phase 1 trial of MCLA-117 for acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: Study of Magrolimab Versus Placebo in Combination With Venetoclax and Azacitidine in Participants With Acute Myeloid Leukemia [Phase 3]
A Phase 3 trial evaluating magrolimab added to venetoclax and azacitidine versus placebo in adults with Acute Myeloid Leukemia was terminate…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML [Phase 3]
Phase 3 trial evaluating Revumenib in combination with azacitidine and venetoclax for adults with NPM1-mutated or KMT2A-rearranged acute mye…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: The Application of CAR-T Cell Therapy in Relapsed and Refractory Malignant Hematologic Tumors [Phase 1, Phase 2]
Ongoing Phase 1/Phase 2 trials are evaluating CAR-T cell therapy for relapsed or refractory malignant hematologic tumors, including aggressi…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant [EARLY_Phase 1]
An early-phase 1 clinical trial is evaluating hyperbaric oxygen therapy in combination with allogeneic peripheral blood stem cell transplant…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: Veliparib and Topotecan With or Without Carboplatin in Treating Patients With Relapsed or Refractory Acute Leukemia, High-Risk Myelodysplasia, or Aggressive Myeloproliferative Disorders [Phase 1]
Phase 1 study of Veliparib with Topotecan, with or without Carboplatin, in relapsed or refractory acute leukemias, high-risk myelodysplastic…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: MIF Involvement in AML
Clinical trial update examining the involvement of macrophage migration inhibitory factor (MIF) in acute myeloid leukemia. The study (NCT039…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: Study of Management and Prognosis of Patients With Acute Myeloblastic Leukemia in Saint-Antoine Hospital
The study at Saint-Antoine Hospital examines management and prognosis of patients with acute myeloid leukemia; it is currently not recruitin…
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CLINICAL_TRIALS trial_result · 2025-04-01Clinical Trial Update: The Role and Mechanism of TCR-T Cells in Immunotherapy for Acute Myeloid Leukemia [EARLY_Phase 1]
An early-phase trial update describing the role and mechanism of TCR-T cell therapy in Acute Myeloid Leukemia, with the study status marked …
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Using the Anticancer Drug Olaparib to Treat Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome With an Isocitrate Dehydrogenase (IDH) Mutation [Phase 2]
Phase 2 trial evaluating olaparib for relapsed/refractory IDH-mutated acute myeloid leukemia or myelodysplastic syndrome; results posted 202…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Phase 1a/1b Study of Aplitabart (IGM-8444) Alone or in Combination in Participants with Relapsed, Refractory, or Newly Diagnosed Cancers [Phase 1]
Aplitabart (IGM-8444) Phase 1a/1b study in solid tumors and various hematologic cancers was terminated.
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Gut Health in Children With Cancer
A clinical trial update indicates that a study on gut health in children with cancer is currently recruiting, enrolling conditions including…
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Selinexor Combined With Azacitidine Therapy in High-Risk Myeloid Neoplasms Patients [Phase 2]
Phase 2 clinical trial evaluating selinexor in combination with azacitidine for high-risk myeloid neoplasms, currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: Eltanexor and Venetoclax in Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia [Phase 1]
A Phase 1 study of eltanexor with venetoclax for relapsed or refractory myelodysplastic syndromes and acute myeloid leukemia is currently re…