Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Mitoxantrone Hydrochloride Liposome, Standard-dose of Cytarabine and Venetoclax in the Treatment of R/R AML [Phase 2]
Phase 2 clinical trial evaluating liposomal mitoxantrone in combination with cytarabine and venetoclax for relapsed/refractory acute myeloid…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: A Study of ASP2215 (Gilteritinib) by Itself, ASP2215 Combined With Azacitidine or Azacitidine by Itself to Treat Adult Patients Who Have Recently Been Diagnosed With Acute Myeloid Leukemia With a FLT3 Gene Mutation and Who Cannot Receive Standard Chemotherapy [Phase 3]
This Phase 3 trial evaluated gilteritinib alone or with azacitidine versus azacitidine alone in adults with newly diagnosed acute myeloid le…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Post-transplant Flotetuzumab for AML [Phase 1]
Phase 1 results update for flotetuzumab in post-transplant acute myeloid leukemia. Results were posted on 2025-09-12.
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Using Gilteritinib to Keep People With Acute Myeloid Leukemia Cancer-free After a Stem Cell Transplant
This clinical trial update discusses using gilteritinib to help maintain remission in patients with acute myeloid leukemia after stem cell t…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: A Study to Investigate Use of Off-the-shelf Natural Killer (NK) Cells (SAR445419) in Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 study evaluating off-the-shelf natural killer cells SAR445419 for relapsed/refractory acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Pitavastatin in Combination With Venetoclax for Chronic Lymphocytic Leukemia or Acute Myeloid Leukemia [Phase 1]
Phase 1 trial of pitavastatin in combination with venetoclax for chronic lymphocytic leukemia or acute myeloid leukemia has completed.
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Venetoclax Combining Chidamide and Azacitidine (VCA) in the Treatment of R/R AML [Phase 2]
Phase 2 clinical trial evaluating venetoclax in combination with chidamide and azacitidine (VCA) for relapsed/refractory acute myeloid leuke…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: A Study Comparing Venetoclax and Azacitidine Plus Cusatuzumab to Venetoclax and Azacitidine in Newly Diagnosed AML Ineligible for Intensive Therapy [Phase 2]
This is a Phase 2 trial comparing venetoclax and azacitidine plus cusatuzumab versus venetoclax and azacitidine in newly diagnosed acute mye…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: Radioimmunotherapy Conditioning With 131I- Apamistamab for Allogeneic Transplant in Relapse/Refractory AML [Phase 2, Phase 3]
This clinical trial evaluates radioimmunotherapy conditioning with 131I-apamistamab before allogeneic stem cell transplantation in patients …
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: A Long Term Follow-up Study of TScan TCR-T Products
This clinical trial update describes a long-term follow-up study of TScan Therapeutics' TCR-T cell therapies for acute myeloid leukemia, acu…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Leptin: A Marker for AML Chemo-Sensitivity
The trial assesses whether leptin can serve as a biomarker for chemotherapy sensitivity in adults with acute myeloid leukemia, and the study…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Combination of Midostaurin and Gemtuzumab Ozogamicin in First-line Standard Therapy for Acute Myeloid Leukemia (MOSAIC) [Phase 1, Phase 2]
A Phase 1/2 trial (MOSAIC) is evaluating the combination of midostaurin and gemtuzumab ozogamicin as part of first-line therapy for acute my…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: PF-05212384 (PKI-587) for t-AML/MDS or de Novo Relapsed or Refractory Acute Myeloid Leukemia (AML) (LAM-PIK) [Phase 2]
Phase 2 trial of PF-05212384 (PKI-587) for therapy-related AML/MDS and de novo/relapsed or refractory AML was terminated. The update indicat…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Cord Blood Transplant in Adults With Blood Cancers [Phase 2]
Phase 2 trial evaluating cord blood transplant in adults with blood cancers is currently recruiting. Conditions include acute myeloid leukem…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Vyxeos® With Clofarabine for Pediatric AML [Phase 1]
Phase 1 trial update of Vyxeos with Clofarabine for relapsed or refractory pediatric acute myeloid leukemia; study currently recruiting.
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors. [NA]
This clinical trial update describes a post-treatment program to identify and manage complications related to oncology or hematology treatme…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow Transplant [Phase 2]
The update describes a Phase 2 study of a modified dose of rabbit anti-thymocyte globulin (rATG) used to condition patients (children and ad…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Allogeneic HCT Using Conditioning Regimen of BuFluATG for AML CR1
Completion notice for NCT07155382 describing allogeneic hematopoietic cell transplantation using BuFluATG conditioning (busulfan, fludarabin…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Study of A Venetoclax-based, Anthracycline-free Regimen in Newly Diagnosed CBFβ::MYH11(+) AML [Phase 2]
A Phase 2 clinical trial evaluating a venetoclax-based, anthracycline-free regimen for newly diagnosed CBFB-MYH11-positive acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: The CLARA Study From the Acute Leukemia French Association (ALFA 0702 Trial) [Phase 2]
The Phase 2 CLARA (ALFA 0702) trial for Acute Myeloid Leukemia has completed.
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Evaluation of Treosulfan Versus Melphalan Conditioning Followed by PTCy in Patients With AML and MDS Undergoing Allogeneic Transplantation [Phase 2]
Phase 2 clinical trial evaluating treosulfan versus melphalan conditioning followed by post-transplant cyclophosphamide in AML and MDS patie…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: uCD7 CART for Relapsed or Refractory CD7 Positive Hematologic Malignancies [Phase 1]
Phase 1 clinical trial evaluating uCD7 CAR-T cells for relapsed or refractory CD7-positive hematologic malignancies is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: DFP-10917 in Combination With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating DFP-10917 in combination with venetoclax for relapsed or refractory acute myeloid leukemia is currentl…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Harmonized Clinical and Biological Database for Integrated Research Into the Management of Pediatric Acute Myeloid Leukemia
A harmonized clinical and biological database project to advance research into the management of pediatric acute myeloid leukemia; status is…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Expression Pattern and Possible Clinical Significance of CD81 In Myeloid Leukemia
This clinical trial update investigates CD81 expression in acute myeloid leukemia and chronic myeloid leukemia and explores its potential cl…