Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: ACHIEVE - Efficacy and Effectiveness of Adoptive Cellular tHerapy wIth Ex-Vivo Expanded Allogeneic γδ T-lymphocytes (TCB008) for Patients With Refractory or Relapsed Acute Myeloid Leukaemia (AML) [Phase 2]
Phase 2 trial ACHIEVE evaluating adoptive cellular therapy with ex-vivo expanded allogeneic γδ T-lymphocytes (TCB008) for refractory or rela…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Study of Liposomal Annamycin in Combination With Cytarabine for the Treatment of Subjects With Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
This entry summarizes a completed Phase 1/2 clinical trial evaluating liposomal annamycin in combination with cytarabine for acute myeloid l…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Retun-to-school Adaptation Program for Children With Cancer [NA]
Clinical trial update indicating the completion of a return-to-school adaptation program study for children with cancer, sponsored by Gazi U…
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies [Phase 3]
A Phase 3 randomized trial evaluating Orca-T in allogeneic stem cell transplantation for hematologic malignancies; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: Bioequivalence of Azacitidine 300 mg Film-Coated Tablets in Adult Patients With Acute Myeloid Leukaemia (AML) [Phase 1]
This clinical trial update reports the bioequivalence assessment of azacitidine 300 mg film-coated tablets in adults with acute myeloid leuk…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies [EARLY_Phase 1]
An early-phase trial evaluating Darzalex Faspro (daratumumab and hyaluronidase-fihj) given before desensitization and allogeneic stem cell t…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: A Study of BL-M11D1 in Patients With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial evaluating BL-M11D1 for relapsed/refractory acute myeloid leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Study of Lisaftoclax (APG-2575) Single Agent and Combination With Therapy in Patients Relapsed/Refractory AML [Phase 1, Phase 2]
This clinical trial update reports that Lisaftoclax (APG-2575) is being studied as a single agent and in combination for relapsed/refractory…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: A Study to Assess the Effect of CC-95251 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndromes [Phase 1]
This Phase 1 trial update reports results for CC-95251 in acute myeloid leukemia and myelodysplastic syndromes. The study has been terminate…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Single Arm Study of Post-transplant Azacitidine and Chidamide for Prevention of Acute Myelogenous Leukemia Relapse [Phase 1, Phase 2]
A single-arm Phase 1/2 clinical trial evaluating post-transplant azacitidine plus chidamide to prevent relapse in acute myeloid leukemia; re…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study
The CREST study update shows the cardiovascular reserve evaluation trial in transplant survivors is currently active but not recruiting, spo…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome [Phase 1]
Phase 1 clinical trial evaluating BH-30236 in patients with relapsed or refractory acute myeloid leukemia and higher-risk myelodysplastic sy…
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CLINICAL_TRIALS other · 2025-09-24Clinical Trial Update: RVU120 Rollover Study [Phase 2]
A Phase 2 rollover study of RVU120 in advanced solid tumors, acute myeloid leukemia, and high-risk myelodysplastic syndrome is not yet recru…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: NTX-301 in MDS/AML [Phase 1]
Phase 1 clinical trial update for NTX-301 in acute myeloid leukemia and myelodysplastic syndromes, including chronic myelomonocytic leukemia…
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CLINICAL_TRIALS trial_result · 2025-09-23Clinical Trial Update: Single Arm Study of Azacitidine and Venetoclax for Treatment of Newly Diagnosed Fit Acute Myeloid Leukemia Patients [NA]
A completed single-arm clinical trial evaluating the combination of azacitidine and venetoclax in newly diagnosed, fit patients with acute m…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Study of SGR-2921 in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1]
Phase 1 study of SGR-2921 in relapsed/refractory acute myeloid leukemia and myelodysplastic syndromes has been terminated.
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Chimeric Antigen Receptor T-cells for The Treatment of AML Expressing CLL-1 Antigen [Phase 1]
Phase 1 clinical trial evaluating CAR-T cells targeting CLL-1 (CLEC12A) for acute myeloid leukemia; the study is active but not recruiting.
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Venetoclax + Azacitidine in Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial update for venetoclax plus azacitidine in acute myeloid leukemia, currently recruiting.
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Venetoclax-Enhanced BUCY vs. Standard BUCY Conditioning in High-Risk AML and MDS Patients Undergoing Allo-HSCT (Ven-BUCY Study) [NA]
A clinical trial evaluating the addition of venetoclax to busulfan/cyclophosphamide conditioning for high-risk acute myeloid leukemia and my…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: An Adaptive Open-label Multicentre Phase 1/2 Trial, to Determine the Recommended Phase 2 Dose of CCTx-001, and to Assess Safety, Tolerability, and Clinical Activity in Patients With Relapsed/Refractory Acute Myeloid Leukaemia [Phase 1, Phase 2]
Adaptive open-label Phase 1/2 trial to determine the recommended Phase 2 dose of CCTx-001 and evaluate safety, tolerability, and clinical ac…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: BSB-1001 in Patients Undergoing HLA-Matched Allogenic Hematopoietic Stem Cell Transplant for AML, ALL or MDS [Phase 1, Phase 2]
Update on a Phase 1/2 trial of BSB-1001 in patients undergoing HLA-matched allogeneic hematopoietic stem cell transplantation for acute myel…
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EMA approval · 2025-09-17EMA Authorised: Mylotarg (gemtuzumab ozogamicin) — Pfizer Europe MA EEIG
The EMA has authorized Mylotarg (gemtuzumab ozogamicin) for acute myeloid leukemia. The product carries orphan medicine designation.
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Monitoring Minimal Residual Disease of Patients With Acute Myelogenous Leukemia or High Grade Myelodysplastic Syndrome
An ongoing University of Rochester clinical trial investigates monitoring minimal residual disease in patients with acute myeloid leukemia o…
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Enasidenib in Combination With Cobimetinib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial evaluating the combination of enasidenib with cobimetinib for relapsed or refractory acute myeloid leukemia; the st…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm [Phase 1]
This document describes an ongoing Phase 1 clinical trial evaluating a genetically modified T-cell immunotherapy for adults with relapsed/re…