Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Treatment of Relapsed or Refractory t(8; 21) AML With Targeted AML1-ETO Neoantigen Cytotoxic T Cells (CTL) [EARLY_Phase 1]
An early-phase 1 trial is evaluating targeted AML1-ETO neoantigen cytotoxic T cells for relapsed or refractory acute myeloid leukemia with t…
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Donor Derived CD117 CAR-T Cells in the Treatment of R/R Acute Myeloid Leukemia [EARLY_Phase 1]
Early-phase trial evaluating donor-derived CD117 CAR-T cells for relapsed/refractory acute myeloid leukemia; the study is currently recruiti…
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: Study to Evaluate Safety and Tolerability of CC-91633 (BMS-986397) in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher-Risk Myelodysplastic Syndromes [Phase 1]
Phase 1 study evaluating safety and tolerability of CC-91633 (BMS-986397) in participants with relapsed or refractory acute myeloid leukemia…
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Prognostic Impacts of Lipid Profile and BMI in Adult AML
A clinical trial from Assiut University will assess how lipid profile and BMI influence prognosis in adults with acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: Hematopoietic Stem Cell Transplantation in the Treatment of Infant Leukemia [Phase 2]
This Phase 2 trial examines hematopoietic stem cell transplantation for infant leukemia and has completed with results posted.
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: Association of Ex Vivo Drug Response ( EVDR) and Clinical Outcome in Acute Myeloid Leukaemia (EXCYTE-2)
This clinical trial update reports on the association between ex vivo drug response and clinical outcomes in acute myeloid leukemia, includi…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of Tuspetinib (HM43239) in patients…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplant [Phase 1, Phase 2]
This clinical trial examines maintenance therapy with decitabine and venetoclax after allogeneic stem cell transplant. It is a Phase 1/2 stu…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AML [Phase 2]
Phase 2 clinical trial evaluating a metabolically optimized, non-cytotoxic, low-dose weekly decitabine/venetoclax regimen in myelodysplastic…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: MRD-guided Treatment in NPM1mut AML Patients [Phase 2]
A Phase 2 trial evaluating MRD-guided treatment in patients with NPM1-mutated acute myeloid leukemia has been terminated, per the clinical t…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: Luveltamab Tazevibulin (STRO-002) in Infants and Children < 12 Years of Age With Relapsed/Refractory CBFA2T3::GLIS2 AML [Phase 1, Phase 2]
A Phase 1/2 trial of Luveltamab Tazevibulin (STRO-002) for relapsed/refractory CBFA2T3::GLIS2 AML in infants and children under 12 has been …
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: A Study to Investigate Natural Killer Cell Engager (SAR443579) With Different Agents in Participants With Hematological Malignancies [Phase 1, Phase 2]
A study evaluating SAR443579, a natural killer cell engager, in combination with different agents for acute myeloid leukemia has been termin…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Ciprofloxacin vs Ceftazidime for Empirical Treatment of High-Risk Neutropenic Fever in Children With Hematologic Malignancies [Phase 4]
Phase 4 trial comparing ciprofloxacin to ceftazidime as empirical therapy for high-risk febrile neutropenia in children with hematologic can…
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CLINICAL_TRIALS other · 2025-08-22Clinical Trial Update: HPB-092 for the Treatment of Relapsed and Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial update for HPB-092 in relapsed and refractory acute myeloid leukemia, with the study listed as not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: A Study of Oral Venetoclax Tablets and Oral Azacitidine as Maintenance Therapy in Adult Participants With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy [Phase 3]
Phase 3 study evaluating maintenance therapy with venetoclax and azacitidine in adults with acute myeloid leukemia in first remission after …
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: MRD-positive AML Clinical Study [NA]
A China-based clinical trial is recruiting adults with MRD-positive acute myeloid leukemia, sponsored by the Institute of Hematology & Blood…
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CLINICAL_TRIALS other · 2025-08-20Clinical Trial Update: QH101 Cell Therapy Relapsed/Refractory(R/R) Acute Myeloid Leukemia(AML) and Myelodysplastic Syndromes(MDS) [Phase 1]
Phase 1 clinical trial update for QH101 Cell Therapy in relapsed/refractory acute myeloid leukemia and myelodysplastic syndromes; the study …
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CLINICAL_TRIALS trial_result · 2025-08-19Clinical Trial Update: Phase 1-2 MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell [Phase 1, Phase 2]
A completed Phase 1/2 study from Stanford evaluated a haploidentical hematopoietic cell transplantation approach using a T-cell depleted gra…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Goal Management Training for Adult Survivors of Childhood Leukemia and Non-Hodgkins Lymphoma With Neurocognitive Sequelae [NA]
Clinical trial update for a study evaluating Goal Management Training for adult survivors of childhood acute lymphoblastic leukemia and chil…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Ivosidenib and Azacitidine With or Without Venetoclax in Adult Patients With Newly Diagnosed IDH1-Mutated AML or MDS/AML Considered Ineligible for Intensive Chemotherapy [Phase 3]
A Phase 3 trial assessing ivosidenib plus azacitidine with or without venetoclax in adults with newly diagnosed IDH1-mutated AML or MDS/AML …
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: A Study of GLB-001 in Patients With Myeloid Malignancies [Phase 1]
A Phase 1 clinical trial evaluating GLB-001 in patients with myeloid malignancies is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: The Efficacy and Safety Assessment of Allogeneic γδ T Cells in Patients With MRD-positive AML After Allo-HSCT [EARLY_Phase 1]
An early-phase 1 trial evaluating the safety and potential efficacy of donor-derived allogeneic gamma-delta T cells in patients with measura…
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: A Study to Evaluate HMPL-306 in Patients With IDH1or IDH2-mutated Acute Myeloid Leukemia [Phase 3]
A Phase 3 study is evaluating HMPL-306 in IDH1- or IDH2-mutated acute myeloid leukemia and is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Clinical Study of Anti-FLT3 CAR-T Cells for the Treatment of Relapsed/Refractory AML [Phase 1]
Phase 1 clinical trial investigating anti-FLT3 CAR-T cells for relapsed/refractory acute myeloid leukemia; currently recruiting.
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: γδ T Cell Therapy for Relapse Prevention in High-Risk AML Post-Transplant [EARLY_Phase 1]
This entry describes an early-phase clinical trial of γδ T cell therapy to prevent relapse in high-risk acute myeloid leukemia after transpl…