Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-09-22Clinical Trial Update: AMD3100 Plus Mitoxantrone, Etoposide and Cytarabine in Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 study of AMD3100 (plerixafor) plus mitoxantrone, etoposide, and cytarabine in adults with acute myeloid leukemia; the trial comple…
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CLINICAL_TRIALS trial_result · 2014-09-18Clinical Trial Update: Dosing Study of Ara-C/EL625/Idarubicin in Refractory and Relapsed AML [Phase 2]
Phase 2 dosing study in refractory and relapsed acute myeloid leukemia evaluating the Ara-C/EL625/idarubicin combination; study status is co…
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CLINICAL_TRIALS trial_result · 2014-09-18Clinical Trial Update: Combination of Sorafenib and Vorinostat in Poor-risk Acute Myelogenous Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS) [Phase 1]
Phase 1 trial update of combining sorafenib with vorinostat in poor-risk acute myeloid leukemia and high-risk myelodysplastic syndromes. The…
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CLINICAL_TRIALS trial_result · 2014-09-18Clinical Trial Update: A Phase 1 Study of the HSP90 Inhibitor, STA-9090 in Subjects With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Blast-phase Chronic Myelogenous Leukemia [Phase 1]
This document reports the completion of a Phase 1 study evaluating the HSP90 inhibitor STA-9090 (ganetespib) in patients with acute myeloid …
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CLINICAL_TRIALS trial_result · 2014-09-18Clinical Trial Update: STA-9090 for Treatment of AML, CML, MDS and Myeloproliferative Disorders [Phase 1]
Phase 1 clinical trial of ganetespib (STA-9090) for acute myeloid leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myelopr…
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CLINICAL_TRIALS withdrawal · 2014-09-18Clinical Trial Update: Aezea® (Cenersen) and Chemotherapy for AML Subjects ≥ 55 Years of Age With No Response to Frontline Induction Course [Phase 2]
A Phase 2 trial of Aezea (Cenersen) with chemotherapy for adults aged 55 and older with Acute Myeloid Leukemia who did not respond to frontl…
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CLINICAL_TRIALS trial_result · 2014-09-12Clinical Trial Update: Clofarabine, Cytarabine, and Thymoglobulin for Allogeneic Transplantation [Phase 2]
Phase 2 trial of Clofarabine, Cytarabine, and Thymoglobulin as part of allogeneic transplantation in myelodysplastic syndromes and acute mye…
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FDA approval · 2014-09-04FDA Approved: BUSULFEX — Supplemental Application (Otsuka America Pharmaceutical, Inc.)
FDA approved a supplemental application for BUSULFEX (busulfan) submitted by Otsuka America Pharmaceutical, Inc.
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CLINICAL_TRIALS trial_result · 2014-08-28Clinical Trial Update: Panobinostat in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia [Phase 2]
A Phase 2 trial evaluating panobinostat in relapsed or refractory acute lymphoblastic leukemia or acute myeloid leukemia was terminated, wit…
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CLINICAL_TRIALS trial_result · 2014-08-27Clinical Trial Update: Vorinostat and Decitabine in Treating Patients With Advanced Solid Tumors or Relapsed or Refractory Non-Hodgkin's Lymphoma, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Chronic Myelogenous Leukemia [Phase 1]
Phase 1 trial of vorinostat combined with decitabine in adults with advanced solid tumors or relapsed/refractory hematologic cancers, includ…
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CLINICAL_TRIALS trial_result · 2014-08-27Clinical Trial Update: Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML) [NA]
A pilot trial evaluating sirolimus in combination with MEC chemotherapy for high-risk acute myeloid leukemia has completed, with results pos…
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CLINICAL_TRIALS trial_result · 2014-08-12Clinical Trial Update: Combination Chemotherapy and Dasatinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial assessing combination chemotherapy with dasatinib for newly diagnosed acute myeloid leukemia; completed with results …
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CLINICAL_TRIALS trial_result · 2014-08-08Clinical Trial Update: Docetaxel in Treating Children With Relapsed or Refractory Acute Lymphoblastic or Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating docetaxel in children with relapsed or refractory acute lymphoblastic leukemia or acute myeloid leukemia; the study…
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CLINICAL_TRIALS trial_result · 2014-08-06Clinical Trial Update: Detection of Residual Disease in Children Receiving Therapy for Acute Myeloid Leukemia or Myelodysplastic Syndrome
The document reports on a clinical trial update focused on detecting residual disease in children undergoing therapy for acute myeloid leuke…
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CLINICAL_TRIALS trial_result · 2014-07-29Clinical Trial Update: Intravenous (IV) Decitabine and Oral Bexarotene for Acute Myelogenous Leukemia (AML) [Phase 1]
A Phase 1 trial evaluating intravenous decitabine in combination with oral bexarotene for acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2014-07-28Clinical Trial Update: Combination Chemotherapy Followed by Melphalan and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Acute Myeloid Leukemia [Phase 1]
Phase 1 trial evaluating combination chemotherapy followed by melphalan and peripheral stem cell transplantation in children with newly diag…
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CLINICAL_TRIALS trial_result · 2014-07-25Clinical Trial Update: Chemotherapy in Treating Children With Recurrent Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial update on chemotherapy for children with recurrent acute myeloid leukemia; the study has completed.
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CLINICAL_TRIALS trial_result · 2014-07-24Clinical Trial Update: Chemotherapy in Treating Children With Relapsed Acute Leukemia, Acute Myeloid Leukemia, or Blastic Phase Chronic Myelogenous Leukemia [Phase 2]
This update reports the completion of a Phase 2 chemotherapy trial in children with relapsed acute leukemia, including acute myeloid leukemi…
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CLINICAL_TRIALS trial_result · 2014-07-24Clinical Trial Update: Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 2]
A Phase 2 trial evaluating a combination chemotherapy regimen in patients with acute myeloid leukemia or myelodysplastic syndromes has compl…
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CLINICAL_TRIALS trial_result · 2014-07-18Clinical Trial Update: Feasibility and Efficiency Study of Leukemic Cell Mobilization With Plerixafor Injection
This clinical trial evaluated the feasibility and efficiency of mobilizing leukemic cells using the CXCR4 inhibitor plerixafor in patients w…
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CLINICAL_TRIALS trial_result · 2014-07-17Clinical Trial Update: Blood Stem Cell Transplantation for the Treatment of Older Patients With Acute Myelogenous Leukemia [Phase 2]
This Phase 2 trial evaluated blood stem cell transplantation as treatment for older adults with acute myeloid leukemia; the study has comple…
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CLINICAL_TRIALS trial_result · 2014-07-17Clinical Trial Update: Trial of Arsenic Trioxide With Ascorbic Acid in the Treatment of Adult Non-Acute Promyelocytic Leukemia (APL) Acute Myelogenous Leukemia [Phase 2]
Phase 2 trial evaluating arsenic trioxide in combination with ascorbic acid for adult acute myeloid leukemia; the study was terminated and r…
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CLINICAL_TRIALS trial_result · 2014-07-09Clinical Trial Update: Phase 2 Study of Temozolomide to Treat Poor Risk / Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 study of temozolomide in patients with poor-risk or refractory acute myeloid leukemia has been completed, with results posted in 201…
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CLINICAL_TRIALS trial_result · 2014-07-09Clinical Trial Update: Peptide Vaccinations to Treat Patients With Low-Risk Myeloid Cancers [Phase 2]
Phase 2 clinical trial update evaluating peptide vaccinations in patients with low-risk myeloid cancers, including myelodysplastic syndrome …
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CLINICAL_TRIALS trial_result · 2014-07-08Clinical Trial Update: DNR and AraC Combined to Fractionated Mylotarg® in Patients With First Relapse of AML [Phase 1, Phase 2]
This Phase 1/2 trial evaluated daunorubicin and cytarabine in combination with fractionated Mylotarg (gemtuzumab ozogamicin) in patients wit…