Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-01-07Clinical Trial Update: AKT Inhibitor MK-2206 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating AKT inhibitor MK-2206 in relapsed or refractory adult acute leukemias completed; results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: Stem Cell Transplantation for Patients With Cancers of the Blood [Phase 2]
Phase 2 trial update reporting results from stem cell transplantation for patients with blood cancers, including chronic myeloid leukemia, c…
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CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: Methods to Enhance the Safety and Effectiveness of Stem Cell Transplants [Phase 2]
Phase 2 clinical trial update on methods to enhance safety and effectiveness of stem cell transplants.
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CLINICAL_TRIALS research · 2015-01-06Clinical Trial Update: Azacytidine Plus FLAG for Relapsed or Refractory AML [Phase 2]
Phase 2 trial evaluating azacitidine plus FLAG for relapsed or refractory acute myeloid leukemia; current status is unknown.
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: Lenalidomide, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial evaluating a combination of lenalidomide, cytarabine, and idarubicin in adults with acute myeloid leukemia; the study…
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: Belinostat and Azacitidine in Treating Patients With Advanced Hematologic Cancers or Other Diseases [Phase 1]
Phase 1 trial update on belinostat plus azacitidine in adults with advanced hematologic cancers. The study has completed enrollment and eval…
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CLINICAL_TRIALS trial_result · 2014-12-18Clinical Trial Update: A Safety Study of Lintuzumab in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome [Phase 1]
This document reports the completion of a Phase 1 safety study of lintuzumab in patients with acute myeloid leukemia and myelodysplastic syn…
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CLINICAL_TRIALS withdrawal · 2014-12-11Clinical Trial Update: Early Enteral Tube Feedings in Children Receiving Chemo for AML/MDS & High Risk Solid Tumors [NA]
This clinical trial update indicates that Vanderbilt University’s study on early enteral tube feedings for children undergoing chemotherapy …
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CLINICAL_TRIALS trial_result · 2014-12-05Clinical Trial Update: Clofarabine/Ara-C Treatment Combined With Reduced-intensity Conditioning Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia in Primary Treatment Failure [Phase 2]
Phase 2 clinical trial evaluating clofarabine/cytarabine with reduced-intensity conditioning allogeneic stem cell transplantation for acute …
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FDA approval · 2014-12-04FDA Approved: IDAMYCIN PFS — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
FDA approved a supplemental application for IDAMYCIN PFS (idarubicin hydrochloride) from Pfizer Laboratories Div Pfizer Inc. The action repr…
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CLINICAL_TRIALS trial_result · 2014-11-25Clinical Trial Update: Azacitidine With or Without Entinostat in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating azacitidine with or without entinostat in patients with myelodysplastic syndromes, chronic myelomonocytic leukemia,…
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CLINICAL_TRIALS trial_result · 2014-11-13Clinical Trial Update: Trial of PXD101 (Belinostat) in Combination With Idarubicin to Treat AML Not Suitable for Standard Intensive Therapy [Phase 1, Phase 2]
This Phase 1/2 trial assessed belinostat (PXD101) in combination with idarubicin for patients with acute myeloid leukemia not eligible for s…
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CLINICAL_TRIALS withdrawal · 2014-11-13Clinical Trial Update: Phase 1 Study Evaluating ZEN003365 in Relapsed/Refractory Lymphoproliferative Malignancies or Relapsed/Refractory AML [Phase 1]
Zenith Epigenetics has withdrawn its Phase 1 trial of ZEN003365 for relapsed/refractory lymphoproliferative disorders and acute myeloid leuk…
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CLINICAL_TRIALS trial_result · 2014-11-11Clinical Trial Update: Oral Clofarabine for Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial evaluating oral clofarabine in patients with acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2014-11-10Clinical Trial Update: Acute Myeloid Leukemia T Cell Depletion to Improve Transplants in Adults With Acute Myeloid Leukemia (BMT CTN 0303) [Phase 2]
Phase 2 trial assessing T cell depletion to improve transplant outcomes in adults with acute myeloid leukemia has completed with results pos…
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CLINICAL_TRIALS trial_result · 2014-11-10Clinical Trial Update: A Two-Step Approach to Bone Marrow Transplant Using Cells From Two Partially-Matched Relatives [Phase 2]
Phase 2 clinical trial investigating a two-step bone marrow transplant using cells from two partially matched relatives was terminated; resu…
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CLINICAL_TRIALS trial_result · 2014-11-07Clinical Trial Update: Decitabine and Bortezomib in Treating Patients With Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial evaluating the combination of decitabine and bortezomib in adults with various subtypes of acute myeloid leukemia h…
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FDA approval · 2014-11-05FDA Approved: DOXORUBICIN HYDROCHLORIDE — Supplemental Application (Fresenius Kabi USA, LLC)
FDA approved a supplemental application for doxorubicin hydrochloride (Fresenius Kabi USA, LLC) under anANDA to support its generic product.
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CLINICAL_TRIALS trial_result · 2014-10-31Clinical Trial Update: A Study of Withdrawal of Immunosuppression and Donor Lymphocyte Infusions Following Allogeneic Transplant for Pediatric Hematologic Malignancies [Phase 2]
Phase 2 trial evaluating withdrawal of immunosuppression and donor lymphocyte infusions after allogeneic transplant in pediatric hematologic…
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CLINICAL_TRIALS research · 2014-10-29Clinical Trial Update: Idarubicin at Different Dosages as Induction Therapy for Newly Diagnosed Acute Myeloid Leukaemia [Phase 4]
This document discusses an ongoing Phase 4 clinical trial evaluating different idarubicin dosing regimens as induction therapy for newly dia…
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FDA approval · 2014-10-25FDA Approved: CYCLOPHOSPHAMIDE — Supplemental Application (Civica, Inc.)
FDA approved a supplemental application for Civica, Inc. to market a generic cyclophosphamide product.
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CLINICAL_TRIALS trial_result · 2014-10-20Clinical Trial Update: Phase 1-2 of Azacitidine + Lenalidomide for Previously Untreated Elderly Patients With Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
A completed Phase 1-2 trial evaluating the combination of azacitidine and lenalidomide in previously untreated elderly patients with acute m…
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CLINICAL_TRIALS trial_result · 2014-10-13Clinical Trial Update: PXD101 in Treating Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 study evaluating belinostat (PXD101) in adults with acute myeloid leukemia, with results posted after completion in 2014.
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CLINICAL_TRIALS trial_result · 2014-10-13Clinical Trial Update: Bone Marrow Transplantation of Patients in Remission Using Partially Matched Relative Donor [Phase 2]
Phase 2 clinical trial evaluating bone marrow transplantation from partially matched relative donors in patients in remission, focusing on a…
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CLINICAL_TRIALS trial_result · 2014-09-29Clinical Trial Update: Lenalidomide in Older Patients With Acute Myeloid Leukemia Without Chromosome 5q Abnormalities [Phase 2]
This Phase 2 trial evaluated lenalidomide in older patients with acute myeloid leukemia without chromosome 5q abnormalities and results were…