A Phase 1 Study of Vorinostat (Suberoylanilide Hydroxamic Acid; SAHA) in Combination With Decitabine in Patients With Advanced Solid Tumors, Relapsed or Refractory Non-Hodgkin's Lymphoma, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Chronic Myelogenous Leukemia in Blast Crisis

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Record identity and dates

Source

ClinicalTrials.gov

Source record ID

NCT00275080

Title field or adapter rule

protocolSection.identificationModule.officialTitle

Ingested At

2026-04-28T10:35:38.562535+00:00

Published At

2014-08-27T00:00:00+00:00

Record Updated At

2014-08-27

Timestamp Basis

source retrieval time was not retained by the feed adapter

Date limitation

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Fields recorded by this source

protocolSection.conditionsModule.conditions

["Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities", "Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)", "Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)", "Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)", "Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)", "Blastic Phase Chronic Myelogenous Leukemia", "Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue", "Nodal Marginal Zone B-cell Lymphoma", "Recurrent Adult Acute Lymphoblastic Leukemia", "Recurrent Adult Acute Myeloid Leukemia", "Recurrent Adult Burkitt Lymphoma", "Recurrent Adult Diffuse Large Cell Lymphoma", "Recurrent Adult Diffuse Mixed Cell Lymphoma", "Recurrent Adult Diffuse Small Cleaved Cell Lymphoma", "Recurrent Adult Immunoblastic Large Cell Lymphoma", "Recurrent Adult Lymphoblastic Lymphoma", "Recurrent Grade 1 Follicular Lymphoma", "Recurrent Grade 2 Follicular Lymphoma", "Recurrent Grade 3 Follicular Lymphoma", "Recurrent Mantle Cell Lymphoma", "Recurrent Marginal Zone Lymphoma", "Recurrent Small Lymphocytic Lymphoma", "Secondary Acute Myeloid Leukemia", "Splenic Marginal Zone Lymphoma", "Stage III Adult Burkitt Lymphoma", "Stage III Adult Diffuse Large Cell Lymphoma", "Stage III Adult Diffuse Mixed Cell Lymphoma", "Stage III Adult Diffuse Small Cleaved Cell Lymphoma", "Stage III Adult Immunoblastic Large Cell Lymphoma", "Stage III Adult Lymphoblastic Lymphoma", "Stage III Grade 1 Follicular Lymphoma", "Stage III Grade 2 Follicular Lymphoma", "Stage III Grade 3 Follicular Lymphoma", "Stage III Mantle Cell Lymphoma", "Stage III Marginal Zone Lymphoma", "Stage III Small Lymphocytic Lymphoma", "Stage IV Adult Burkitt Lymphoma", "Stage IV Adult Diffuse Large Cell Lymphoma", "Stage IV Adult Diffuse Mixed Cell Lymphoma", "Stage IV Adult Diffuse Small Cleaved Cell Lymphoma", "Stage IV Adult Immunoblastic Large Cell Lymphoma", "Stage IV Adult Lymphoblastic Lymphoma", "Stage IV Grade 1 Follicular Lymphoma", "Stage IV Grade 2 Follicular Lymphoma", "Stage IV Grade 3 Follicular Lymphoma", "Stage IV Mantle Cell Lymphoma", "Stage IV Marginal Zone Lymphoma", "Stage IV Small Lymphocytic Lymphoma", "Unspecified Adult Solid Tumor, Protocol Specific", "Untreated Adult Acute Lymphoblastic Leukemia", "Untreated Adult Acute Myeloid Leukemia"]

protocolSection.statusModule.lastUpdatePostDateStruct.date

"2014-08-27"

protocolSection.identificationModule.nctId

"NCT00275080"

protocolSection.identificationModule.officialTitle

"A Phase 1 Study of Vorinostat (Suberoylanilide Hydroxamic Acid; SAHA) in Combination With Decitabine in Patients With Advanced Solid Tumors, Relapsed or Refractory Non-Hodgkin\u0027s Lymphoma, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Chronic Myelogenous Leukemia in Blast Crisis"

protocolSection.statusModule.overallStatus

"COMPLETED"

protocolSection.designModule.phases

["PHASE1"]

protocolSection.statusModule.resultsFirstPostDateStruct.date

""

Study condition terms

• Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities (protocolSection.conditionsModule.conditions)
• Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) (protocolSection.conditionsModule.conditions)
• Adult Acute Myeloid Leukemia With t(15;17)(q22;q12) (protocolSection.conditionsModule.conditions)
• Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) (protocolSection.conditionsModule.conditions)
• Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) (protocolSection.conditionsModule.conditions)
• Blastic Phase Chronic Myelogenous Leukemia (protocolSection.conditionsModule.conditions)
• Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue (protocolSection.conditionsModule.conditions)
• Nodal Marginal Zone B-cell Lymphoma (protocolSection.conditionsModule.conditions)
• Recurrent Adult Acute Lymphoblastic Leukemia (protocolSection.conditionsModule.conditions)
• Recurrent Adult Acute Myeloid Leukemia (protocolSection.conditionsModule.conditions)
• Recurrent Adult Burkitt Lymphoma (protocolSection.conditionsModule.conditions)
• Recurrent Adult Diffuse Large Cell Lymphoma (protocolSection.conditionsModule.conditions)
• Recurrent Adult Diffuse Mixed Cell Lymphoma (protocolSection.conditionsModule.conditions)
• Recurrent Adult Diffuse Small Cleaved Cell Lymphoma (protocolSection.conditionsModule.conditions)
• Recurrent Adult Immunoblastic Large Cell Lymphoma (protocolSection.conditionsModule.conditions)
• Recurrent Adult Lymphoblastic Lymphoma (protocolSection.conditionsModule.conditions)
• Recurrent Grade 1 Follicular Lymphoma (protocolSection.conditionsModule.conditions)
• Recurrent Grade 2 Follicular Lymphoma (protocolSection.conditionsModule.conditions)
• Recurrent Grade 3 Follicular Lymphoma (protocolSection.conditionsModule.conditions)
• Recurrent Mantle Cell Lymphoma (protocolSection.conditionsModule.conditions)
• Recurrent Marginal Zone Lymphoma (protocolSection.conditionsModule.conditions)
• Recurrent Small Lymphocytic Lymphoma (protocolSection.conditionsModule.conditions)
• Secondary Acute Myeloid Leukemia (protocolSection.conditionsModule.conditions)
• Splenic Marginal Zone Lymphoma (protocolSection.conditionsModule.conditions)
• Stage III Adult Burkitt Lymphoma (protocolSection.conditionsModule.conditions)
• Stage III Adult Diffuse Large Cell Lymphoma (protocolSection.conditionsModule.conditions)
• Stage III Adult Diffuse Mixed Cell Lymphoma (protocolSection.conditionsModule.conditions)
• Stage III Adult Diffuse Small Cleaved Cell Lymphoma (protocolSection.conditionsModule.conditions)
• Stage III Adult Immunoblastic Large Cell Lymphoma (protocolSection.conditionsModule.conditions)
• Stage III Adult Lymphoblastic Lymphoma (protocolSection.conditionsModule.conditions)
• Stage III Grade 1 Follicular Lymphoma (protocolSection.conditionsModule.conditions)
• Stage III Grade 2 Follicular Lymphoma (protocolSection.conditionsModule.conditions)
• Stage III Grade 3 Follicular Lymphoma (protocolSection.conditionsModule.conditions)
• Stage III Mantle Cell Lymphoma (protocolSection.conditionsModule.conditions)
• Stage III Marginal Zone Lymphoma (protocolSection.conditionsModule.conditions)
• Stage III Small Lymphocytic Lymphoma (protocolSection.conditionsModule.conditions)
• Stage IV Adult Burkitt Lymphoma (protocolSection.conditionsModule.conditions)
• Stage IV Adult Diffuse Large Cell Lymphoma (protocolSection.conditionsModule.conditions)
• Stage IV Adult Diffuse Mixed Cell Lymphoma (protocolSection.conditionsModule.conditions)
• Stage IV Adult Diffuse Small Cleaved Cell Lymphoma (protocolSection.conditionsModule.conditions)
• Stage IV Adult Immunoblastic Large Cell Lymphoma (protocolSection.conditionsModule.conditions)
• Stage IV Adult Lymphoblastic Lymphoma (protocolSection.conditionsModule.conditions)
• Stage IV Grade 1 Follicular Lymphoma (protocolSection.conditionsModule.conditions)
• Stage IV Grade 2 Follicular Lymphoma (protocolSection.conditionsModule.conditions)
• Stage IV Grade 3 Follicular Lymphoma (protocolSection.conditionsModule.conditions)
• Stage IV Mantle Cell Lymphoma (protocolSection.conditionsModule.conditions)
• Stage IV Marginal Zone Lymphoma (protocolSection.conditionsModule.conditions)
• Stage IV Small Lymphocytic Lymphoma (protocolSection.conditionsModule.conditions)
• Unspecified Adult Solid Tumor, Protocol Specific (protocolSection.conditionsModule.conditions)
• Untreated Adult Acute Lymphoblastic Leukemia (protocolSection.conditionsModule.conditions)
• Untreated Adult Acute Myeloid Leukemia (protocolSection.conditionsModule.conditions)

Intervention details are not present in the imported fields for this record. No drug-condition relationship is inferred from co-listing.

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