Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies [Phase 1, Phase 2]
A first-in-human study evaluating HLA partially to fully matched allogeneic, cryopreserved deceased donor bone marrow transplantation for va…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
A clinical trial update describing a study to learn more about the health of persons with Down syndrome after treatment for acute leukemia.
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CLINICAL_TRIALS withdrawal · 2026-02-24Clinical Trial Update: Cryopreserved MMUD BM With PTCy for Hematologic Malignancies [Phase 1]
Phase 1 trial of cryopreserved MMUD bone marrow with post-transplant cyclophosphamide for hematologic malignancies has been withdrawn.
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 clinical trial evaluating imatinib mesylate in combination with chemotherapy for newly diagnosed Philadelphia chromosome-positive ac…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies [Phase 1]
This clinical trial update describes a Phase 1 study of Orca-Q for patients with hematologic malignancies undergoing allogeneic stem cell tr…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCT [NA]
Clinical trial update indicates ongoing recruitment for a study evaluating CD45RA-depleted peripheral stem cell addback to prevent viral or …
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution
A pharmacokinetic study is evaluating how crushing venetoclax tablets and dissolving them in solution affects drug exposure, to assess alter…
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CLINICAL_TRIALS withdrawal · 2026-02-18Clinical Trial Update: SPARK-ALL: Calaspargase Pegol in Adults With ALL [Phase 2, Phase 3]
Clinical trial SPARK-ALL evaluating Calaspargase Pegol in adults with acute lymphoblastic leukemia was terminated (Phase 2/3).
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Low-Intensity Chemotherapy, Ponatinib and Blinatumomab in Treating Patients With Philadelphia Chromosome-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia [Phase 2]
This Phase 2 clinical trial evaluates low-intensity chemotherapy in combination with ponatinib and blinatumomab for Philadelphia chromosome-…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Inotuzumab Ozogamicin in Treating Patients With B-cell Acute Lymphocytic Leukemia With Positive Minimal Residual Disease [Phase 2]
Phase 2 clinical trial update evaluating Besponsa (Inotuzumab ozogamicin) for B-cell acute lymphoblastic leukemia with positive minimal resi…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant [Phase 2]
A Phase 2 clinical trial update evaluating busulfan, fludarabine phosphate, and post-transplant cyclophosphamide in patients with hematologi…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/Leukemia [Phase 2]
Phase 2 clinical trial update describing a combination chemotherapy regimen for relapsed or refractory acute lymphoblastic leukemia, lymphob…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: The Effect of Mandala on Anxiety and Fear Levels in Children With Leukemia Before Intrathecal Chemotherapy Treatment [NA]
A clinical trial at Ege University is evaluating whether Mandala affects anxiety and fear levels in pediatric leukemia patients before intra…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Pilot Study of Anti-CD19 Chimeric Antigen Receptor T Cells (CAR-T Cells) for the Treatment of Relapsed/Refractory CD19+ Malignancies [Phase 1]
Phase 1 pilot study evaluating anti-CD19 CAR-T cells for relapsed/refractory CD19+ malignancies; the trial is currently recruiting at the Un…
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Innovative Prosthetic Systems for Pediatric Limb Loss to Accommodate Growth [NA]
Clinical trial update on innovative prosthetic systems for children with limb deficiencies that can accommodate growth; the study is current…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Exploring the Effect of Calaspargase Pegol on the Coagulation System in Pediatric Acute Lymphoblastic Leukemia (ALL) Patients: Pilot Study
A Mayo Clinic-sponsored pilot clinical trial is evaluating how calaspargase pegol impacts the coagulation system in pediatric acute lymphobl…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma [Phase 2]
A Phase 2 clinical trial update from St. Jude Children's Research Hospital recruiting for therapy in newly diagnosed B-cell precursor acute …
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: Inotuzumab Ozogamicin for Children With MRD Positive CD22+ Lymphoblastic Leukemia [Phase 2]
This Phase 2 trial evaluating inotuzumab ozogamicin in children with MRD-positive CD22+ acute lymphoblastic leukemia was terminated.
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Weight Gain in Pediatric Leukemia Survivors [NA]
A clinical trial examining weight gain in pediatric leukemia survivors, currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Immune-targeted Combination With Chemotherapy for Acute Leukemia of Ambiguous Lineage [NA]
A clinical trial update notes a planned immune-targeted combination with chemotherapy for adult acute leukemia with ambiguous lineage (ALL/M…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: A Study of 19-28z/IL-18 in People With Acute Lymphoblastic Leukemia (ALL) [Phase 1]
A Phase 1 study of 19-28z/IL-18 in adults with acute lymphoblastic leukemia is ongoing, including Philadelphia-negative and Philadelphia-pos…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Autologous CD22 CAR T Cells Following Commercial CD19 CAR T Cells in B Cell Malignancies [Phase 1]
Phase 1 trial evaluating autologous CD22-directed CAR T cells after prior commercial CD19-directed CAR T therapy in patients with B-cell mal…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: A 3-cohort Randomized Study Evaluating the Role of New Immunotherapeutic Agents and of Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Frontline Therapy of Adults With Acute Lymphoblastic Leukemia [Phase 2, Phase 3]
This Clinical Trials entry describes a multicohort randomized study evaluating new immunotherapies and allogeneic hematopoietic stem cell tr…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Electronic Health Mindfulness-based Music Therapy Intervention for Patients Undergoing Allogeneic Stem Cell Transplantation [NA]
The document updates a clinical trial evaluating an electronic health mindfulness-based music therapy intervention for patients undergoing a…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: A Study to Evaluate the Tolerability, Safety, and Efficacy of an Anti-CD19 CAR-T Product in Patients With B-cell Lymphoproliferative Disorders [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a CD19-targeted CAR-T therapy for B-cell lymphoproliferative disorders has completed, assessing tolera…