Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Ponatinib Plus Chemotherapy in Acute Lymphoblastic Leukemia Patients [Phase 2]
Phase 2 clinical trial evaluating ponatinib in combination with chemotherapy for acute lymphoblastic leukemia; currently not recruiting.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Phase II Study of the Combination of Ponatinib With Mini-hyper CVD Chemotherapy and Venetoclax in Patients With Relapsed or Refractory T-cell Acute Lymphoblastic Leukemia [Phase 2]
Phase II trial evaluating the combination of ponatinib with mini-hyper CVD chemotherapy and venetoclax in relapsed or refractory T-cell acut…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant [Phase 1]
A Phase 1 clinical trial evaluating Revumenib for acute leukemia in patients after allogeneic stem cell transplant; the study is currently r…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: CiproPAL (Ciprofloxacin Prophylaxis in Acute Leukaemia) [NA]
This clinical trial update describes CiproPAL, a ciprofloxacin prophylaxis study in patients with acute lymphoblastic leukemia, which is cur…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Symptom Cluster Heterogeneity and Gut Microbiota Mechanisms in Childhood Cancer Survivors
A pediatric cancer survivor study focusing on symptom cluster heterogeneity and gut microbiota mechanisms is currently recruiting, including…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies [Phase 2]
Phase 2 clinical trial update evaluating TCRαβ-depleted progenitor cell graft with added memory T-cell donor lymphocyte infusion and selecti…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: CApivasertib, Venetoclax And Low-intensity chemotheRapY for Adults With ALL/LBL [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the combination of capivasertib, venetoclax, and low-intensity chemotherapy in adults with acute ly…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Using Text Messages to Improve Oral Chemotherapy for Adolescents and Adults With Acute Lymphoblastic Leukemia [NA]
A University of Chicago-sponsored study tests whether text-message reminders can improve adherence to oral chemotherapy in adolescents and a…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Feasibility and Safety of Collecting and Combining Autologous Hematopoietic Stem Cells With Chimeric Antigen Receptor (CAR) T-Cell Therapy in Subjects With Relapsed/Refractory Hematological Malignancies [Phase 1]
A Phase 1 study evaluating feasibility and safety of collecting autologous hematopoietic stem cells and combining them with CAR T-cell thera…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: CD34+ Transplants for Leukemia and Lymphoma [Phase 2]
A Phase 2 clinical trial update on CD34+ transplants for acute myeloid leukemia and acute lymphoblastic leukemia, currently not recruiting.
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma [Phase 4]
Phase 4 clinical trial update from St. Jude focusing on identifying information needed to guide treatment induction in newly diagnosed acute…
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CLINICAL_TRIALS guidance · 2026-03-02Clinical Trial Update: Recommendations for the Treatment of Children With Acute Lymphoblastic Leukemia in the GFAOP
The document provides recommendations for treating children with acute lymphoblastic leukemia within the GFAOP network. It outlines updated …
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Leukemias [Phase 1, Phase 2]
Clinical trial update on an anti-CD19 CAR-T cell therapy being evaluated in Phase 1/Phase 2 for various leukemias and lymphoid cancers; recr…
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CLINICAL_TRIALS other · 2026-03-02Clinical Trial Update: Efficacy and Safety of Chemotherapy Combined With CAR-T Cells in Newly Diagnosed Adult Patients With Ph- B-ALL [NA]
A clinical trial update describes a study evaluating chemotherapy combined with CAR-T cell therapy in newly diagnosed adult patients with Ph…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Clinical Trial of CMD63 Chimeric Antigen Receptor T-cell (CAR T-cell) in Children With Acute Lymphoblastic Leukemia (ALL) [Phase 1]
Phase 1 clinical trial evaluating CMD63 CAR T-cell therapy in children with relapsed or refractory B-cell acute lymphoblastic leukemia, curr…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Efficacy and Safety of TKI Combined With Chemotherapy and Sequential CAR-T Cells in ND Adult Patients With Ph+ ALL [NA]
An ongoing clinical trial evaluating a tyrosine kinase inhibitor combined with chemotherapy and sequential CAR-T cell therapy in newly diagn…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies [Phase 2]
Phase 2 clinical trial update describing a donor stem cell transplant conditioning regimen with treosulfan, fludarabine, and total-body irra…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Efficacy and Toxicity of Blinatumomab in the French ATU for Adult BCP-ALL R/R, or With MRD+ (FRENCH-CYTO)
This completed French ATU study assessed the efficacy and safety of blinatumomab in adults with B-cell precursor acute lymphoblastic leukemi…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Expanded Access Program for OOS Obe-cel
Autolus Limited announced an Expanded Access Program for Obe-cel, its CAR-T therapy, to treat adults with acute lymphoblastic leukemia, incl…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood [Phase 2]
Phase 2 clinical trial evaluating co-transplant of an unmodified haplo-identical graft with cord blood; the study targets acute graft-versus…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Pharmacokinetics of Dexamethasone in Childhood ALL and Reduction in Bone Mineral Density
A pediatric pharmacokinetics study of dexamethasone in childhood acute lymphoblastic leukemia and assessment of dexamethasone-related bone m…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Phase 2 Study Assessing the Clinical Activity and Safety of Obecabtagene Autoleucel as a Consolidation in Patients With Newly Diagnosed High-risk B-cell Acute Lymphocytic Leukemia (ALL) [Phase 2]
Phase 2 study evaluating obecabtagene autoleucel as consolidation therapy in newly diagnosed high-risk B-cell acute lymphoblastic leukemia; …
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: A Study of BN104 in the Treatment of Acute Leukemia [Phase 1, Phase 2]
BN104 is being studied in Phase 1/2 trials for acute leukemia; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia [Phase 2]
The document describes a Phase 2 clinical trial evaluating a four-drug regimen (blinatumomab, methotrexate, cytarabine, and ponatinib) for P…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: CIK Cell Therapy for Relapsed or Refractory Acute B-Lymphoblastic Leukemia: Prognostic Impact on Patients With Early CAR-T Cell Dysfunction [NA]
Clinical trial update on cytokine-induced killer (CIK) cell therapy for relapsed or refractory B-cell acute lymphoblastic leukemia, assessin…