Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Nilotinib and Imatinib Mesylate After Donor Stem Cell Transplant in Treating Patients With ALL or CML [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating the use of nilotinib and imatinib after donor stem cell transplant in patients with acute ly…
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Haploidentical Allogeneic Transplant With Post-transplant Infusion of Regulatory T-cells [Phase 1, Phase 2]
A terminated Phase 1/2 clinical trial evaluated haploidentical allogeneic transplantation with post-transplant regulatory T-cell infusion in…
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FDA approval · 2017-05-09FDA Approved: CLOFARABINE — Original Application (Zydus Lifesciences Limited)
FDA approves a generic version of Clofarabine under Original Application ANDA204029 from Zydus Lifesciences Limited, for relapsed or refract…
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CLINICAL_TRIALS trial_result · 2017-05-04Clinical Trial Update: Pentostatin and Lymphocyte Infusion in Preventing Graft Rejection in Patients Who Have Undergone Donor Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating pentostatin and lymphocyte infusion to prevent graft rejection after donor stem cell transplantation—compl…
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial update evaluating whether adding donor stem cell transplantation to combination chemotherapy improves outcomes in adu…
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Genetically Modified Haploidentical Natural Killer Cell Infusions for B-Lineage Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 trial evaluating genetically modified haploidentical natural killer cell infusions for B-lineage acute lymphoblastic leukemia has co…
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Compassionate Use of Erwinase For Pediatric Patients With Acute Lymphoblastic Leukemia Or Non Hodgkins Lymphoma [Phase 1]
Phase 1 compassionate-use update of Erwinase (L-asparaginase from Erwinia chrysanthemi) for pediatric acute lymphoblastic leukemia and non-H…
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CLINICAL_TRIALS research · 2017-04-26Clinical Trial Update: DNA Analysis of Bone Marrow and Blood Samples From Young Patients With Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia
This completed clinical trial updates DNA analysis of bone marrow and blood samples from young patients with acute myeloid leukemia or acute…
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: ALL2008 Protocol for Childhood Acute Lymphoblastic Leukemia (ALL) - 6MP Consolidation Therapy [Phase 3]
Phase 3 trial evaluating consolidation therapy with 6-mercaptopurine in children with acute lymphoblastic leukemia within the ALL2008 protoc…
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: Metabolic Syndrome in Young Patients With Acute Lymphoblastic Leukemia in Remission
This is a completed clinical trial assessing metabolic syndrome and long-term health effects in young patients with acute lymphoblastic leuk…
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CLINICAL_TRIALS research · 2017-04-21Clinical Trial Update: ALL2008 Protocol for Childhood Acute Lymphoblastic Leukemia Intermittent Versus Continuous PEG Asparaginase [Phase 3]
Phase 3 pediatric trial comparing intermittent versus continuous PEG-asparaginase in childhood acute lymphoblastic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: MS-275 and GM-CSF in Treating Patients With Myelodysplastic Syndrome and/or Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating MS-275 (entinostat) in combination with GM-CSF in adults with myelodysplastic syndromes and/or relapsed or refracto…
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Study Evaluating Inotuzumab Ozogamicin In Acute Lymphocytic Leukemia [Phase 2]
A Pfizer-sponsored Phase 2 trial evaluating inotuzumab ozogamicin in acute lymphoblastic leukemia has completed and posted results in April …
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Use of Saline-Washed Platelet and Red Cell Transfusions in Adult Acute Leukemia
This clinical trial update reports results from a completed study evaluating saline-washed platelet and red cell transfusions in adults with…
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CLINICAL_TRIALS trial_result · 2017-04-10Clinical Trial Update: Kidney Dysfunction in Children and Young Adults Who Have Received Methotrexate for Acute Lymphoblastic Leukemia
The trial update reports instances of kidney dysfunction in children and young adults treated with methotrexate for acute lymphoblastic leuk…
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: A Safety and Tolerability Study of CDX-301 With or Without Plerixafor for Stem Cell Mobilization in Matched Related Allogeneic Donor/Recipient Sibling Transplant Pairs [Phase 2]
A Phase 2 safety and tolerability trial evaluating CDX-301 with or without plerixafor for stem cell mobilization in matched related donor/re…
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CLINICAL_TRIALS trial_result · 2017-04-06Clinical Trial Update: Nonmyeloablative Allo SCT for the Treatment of Hematologic Disorders [Phase 2]
Phase 2 clinical trial evaluating nonmyeloablative allogeneic stem cell transplantation for various hematologic disorders has completed.
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Plerixafor and Filgrastim For Mobilization of Donor Peripheral Blood Stem Cells Before A Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies [NA]
A terminated clinical trial evaluated mobilizing donor peripheral blood stem cells with plerixafor and filgrastim before donor transplant in…
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: Treatment of Older Adults With Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial results for treating older adults with acute lymphoblastic leukemia have been posted.
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: Safety Assessment of Two Schedules of Intravenous Infusions of SNS-595 for the Treatment of Hematologic Malignancies [Phase 1]
Phase 1 clinical trial update describing safety assessments for two infusion schedules of SNS-595 in patients with hematologic malignancies.…
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Biological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leukemia, or Acute Lymphoblastic Leukemia Who Are Undergoing Stem Cell Transplantation [Phase 1, Phase 2]
A Phase 1/2 clinical trial update reports completion of a study evaluating an investigational biological therapy in adults with advanced mye…
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CLINICAL_TRIALS trial_result · 2017-03-17Clinical Trial Update: Use of Hyperbaric Oxygen Therapy to Improve Umbilical Cord Blood Stem Cell Homing and Subsequent Engraftment [NA]
Clinical trial results posted on using hyperbaric oxygen therapy to improve umbilical cord blood stem cell homing and engraftment in patient…
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CLINICAL_TRIALS research · 2017-03-16Clinical Trial Update: Competitive Transfer of αCD19-TCRz-CD28 and αCD19-TCRz-CD137 CAR-T Cells for B-cell Leukemia/Lymphoma [Phase 1, Phase 2]
This document describes a Phase 1/2 clinical trial evaluating competitive transfer of two αCD19-TCRz-CAR-T cell constructs (one with CD28 an…
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CLINICAL_TRIALS trial_result · 2017-03-14Clinical Trial Update: Exergaming Intervention in ALL Patients [NA]
This document provides an update on a completed clinical trial evaluating an exergaming intervention in patients with Acute Lymphoblastic Le…
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Donor Lymphocyte Infusion in Treating Patients With Persistent, Relapsed, or Progressing Cancer After Donor Hematopoietic Cell Transplant [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating donor lymphocyte infusion for patients with persistent, relapsed, or progressing cancer after donor hema…