Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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FDA approval · 2019-01-03FDA Approved: ONCASPAR — Supplemental Application (Servier Pharmaceuticals LLC)
The FDA approved a supplemental application for ONCASPAR (pegaspargase) submitted by Servier Pharmaceuticals LLC.
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FDA approval · 2018-12-21FDA Approved: DASATINIB — Supplemental Application (Prasco Laboratories)
FDA approved a supplemental application for dasatinib submitted by Prasco Laboratories.
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FDA approval · 2018-12-20FDA Approved: ASPARLAS — Original Application (Servier Pharmaceuticals LLC)
The FDA approved ASPARLAS (calaspargase pegol) from Servier Pharmaceuticals as a treatment for acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2018-12-10Clinical Trial Update: Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia [Phase 3]
A Phase 3 trial evaluated whether adding lestaurtinib to standard chemotherapy improves outcomes in children with newly diagnosed acute lymp…
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CLINICAL_TRIALS trial_result · 2018-11-20Clinical Trial Update: Anti-CD19 CAR-T Therapy Combine With HSCT to Treat MRD+ B-cell Malignancies [Phase 1, Phase 2]
A clinical trial update describes an anti-CD19 CAR-T therapy combined with hematopoietic stem cell transplantation for MRD-positive B-cell m…
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CLINICAL_TRIALS trial_result · 2018-10-31Clinical Trial Update: Nonmyeloablative Preparative Regimen Using Mylotarg for Patients With High Risk Acute Myeloid Leukemia (AML), Acute Lymphocytic Leukemia (ALL), Chronic Myeloid Leukemia (CML) and Myelodysplastic Syndrome (MDS) [Phase 2, Phase 3]
A nonmyeloablative preparative regimen using Mylotarg (gemtuzumab ozogamicin) was studied in Phase 2/Phase 3 trials for high-risk acute myel…
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CLINICAL_TRIALS trial_result · 2018-10-23Clinical Trial Update: GIMEMA LAL 0496: High-dose Anthracycline in the Induction Regimen for the Treatment of Adult ALL. [Phase 2]
Phase 2 clinical trial evaluating high-dose anthracycline added to induction therapy for adults with acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2018-10-17Clinical Trial Update: G-CSF Alone or Combination With GM-CSF on Prevention and Treatment of Infection in Children With Malignant Tumor [Phase 4]
A Phase 4 clinical trial evaluating G-CSF alone or in combination with GM-CSF for prevention and treatment of infection in children with mal…
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CLINICAL_TRIALS trial_result · 2018-10-09Clinical Trial Update: Bortezomib and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 study evaluating bortezomib with combination chemotherapy in adults with relapsed or refractory acute lymphoblastic leukemia; trial …
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CLINICAL_TRIALS trial_result · 2018-10-01Clinical Trial Update: A Dose-finding Study of the Bromodomain (Brd) Inhibitor OTX015/ Birabresib (MK-8628) in Hematologic Malignancies (MK-8628-001) [Phase 1]
Phase 1 dose-finding study of the bromodomain inhibitor birabresib (OTX015/MK-8628) in hematologic malignancies has completed with results p…
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FDA approval · 2018-09-28FDA Approved: BUSULFEX — Supplemental Application (Otsuka America Pharmaceutical, Inc.)
FDA approved a supplemental application for Busultex (busulfan) filed by Otsuka America Pharmaceutical, Inc. The action updates the labeling…
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FDA approval · 2018-09-27FDA Approved: DAUNORUBICIN HYDROCHLORIDE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved a supplemental application for daunorubicin hydrochloride (Hikma Pharmaceuticals USA Inc.).
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CLINICAL_TRIALS research · 2018-09-07Clinical Trial Update: WT1 Immunity Via DNA Fusion Gene Vaccination in Haematological Malignancies by Intramuscular Injection Followed by Intramuscular Electroporation [Phase 2]
Phase 2 clinical trial investigating WT1 DNA fusion gene vaccination with intramuscular injection and electroporation for haematological mal…
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CLINICAL_TRIALS trial_result · 2018-09-06Clinical Trial Update: Calaspargase Pegol or Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 trial evaluating calaspargase pegol or pegaspargase with combination chemotherapy in younger patients with newly diagnosed high-risk…
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CLINICAL_TRIALS trial_result · 2018-08-31Clinical Trial Update: HLA 10/10 Matched Unrelated Donor vs Haploidentical Allogenic Hematopoietic Stem Cell Transplantation [Phase 3]
Phase 3 trial comparing HLA 10/10 matched unrelated donor versus haploidentical allogeneic hematopoietic stem cell transplantation for acute…
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CLINICAL_TRIALS trial_result · 2018-08-24Clinical Trial Update: Treatment for Executive Dysfunction in Adult Survivors of Childhood Acute Lymphoblastic Leukemia [NA]
Clinical trial update on treatment for executive dysfunction in adult survivors of childhood acute lymphoblastic leukemia has completed; res…
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CLINICAL_TRIALS trial_result · 2018-08-21Clinical Trial Update: Pediatric Philadelphia Positive Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial update for pediatric Philadelphia-positive acute lymphoblastic leukemia has completed with results posted.
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FDA approval · 2018-08-13FDA Approved: IMATINIB — Original Application (Dr.Reddy's Laboratories Inc)
FDA approved the original application for imatinib from Dr. Reddy's Laboratories Inc, enabling the generic product to be marketed in the Uni…
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CLINICAL_TRIALS trial_result · 2018-08-07Clinical Trial Update: Busulfan Plus Clofarabine Followed by Allogeneic Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 trial evaluating busulfan plus clofarabine followed by allogeneic hematopoietic stem cell transplantation for leukemia and lymphoma.
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CLINICAL_TRIALS research · 2018-07-30Clinical Trial Update: Tyrosine Kinase Inhibitors and Low Intensity Chemotherapy in Ph+ ALL
An update on a clinical trial evaluating tyrosine kinase inhibitors combined with low-intensity chemotherapy in Philadelphia chromosome-posi…
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FDA approval · 2018-07-27FDA Approved: LEUCOVORIN CALCIUM — Original Application (Fresenius Kabi USA, LLC)
FDA approved a generic Leucovorin Calcium under ANDA 207226 for Fresenius Kabi USA, LLC.
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CLINICAL_TRIALS withdrawal · 2018-07-26Clinical Trial Update: Trial Evaluating the Efficacy and Safety of Daratumumab in Subjects With Relapsed/Refractory B-cell or T-cell Precursor Acute Lymphoblastic Leukemia (ALL) [Phase 2]
A Phase 2 trial evaluating daratumumab for relapsed/refractory B-cell or T-cell precursor acute lymphoblastic leukemia has been withdrawn.
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CLINICAL_TRIALS research · 2018-07-24Clinical Trial Update: Rituximab+mVPDL for CD20(+) Adult Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial evaluating Rituximab in combination with mVPDL for CD20-positive precursor cell lymphoblastic leukemia-lymphoma in ad…
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Donor-specific Allogeneic Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia (ALL) [Phase 2]
A Phase 2 clinical trial investigating donor-specific allogeneic hematopoietic cell transplantation for acute lymphoblastic leukemia has bee…
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Steroid-Induced Osteoporosis in the Pediatric Population - Canadian Incidence Study
This completed Canadian incidence study examines the occurrence of steroid-induced osteoporosis in pediatric patients. It highlights the bur…