Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-05-10Clinical Trial Update: CD19 Chimeric Antigen Receptor (CAR)-Modified T Cell Therapy in Treating Patients With B-cell Malignancies [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating a CD19 CAR-T cell therapy for treating B-cell malignancies, including acute lymphoblastic leukemia and…
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CLINICAL_TRIALS trial_result · 2019-05-10Clinical Trial Update: Anti-CD19 CAR-T Therapy Bridging to HSCT for CD19+ B-Cell Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial update evaluating anti-CD19 CAR-T therapy used as a bridging therapy to hematopoietic stem cell transplant for CD19…
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CLINICAL_TRIALS trial_result · 2019-05-01Clinical Trial Update: Safety and Efficacy of BL-8040 for the Mobilization of Donor Hematopoietic Stem Cells and Allogeneic Transplantation in Patients With Advanced Hematological Malignancies [Phase 2]
Phase 2 clinical trial evaluating BL-8040 for mobilizing donor hematopoietic stem cells to enable allogeneic transplantation in patients wit…
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CLINICAL_TRIALS trial_result · 2019-04-23Clinical Trial Update: Determinants of Mercaptopurine Toxicity in Paediatric Acute Lymphoblastic Leukemia Maintenance Therapy [Phase 4]
Phase 4 clinical trial investigating determinants of mercaptopurine toxicity during maintenance therapy for pediatric acute lymphoblastic le…
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FDA approval · 2019-04-18FDA Approved: BLINCYTO — Supplemental Application (Amgen, Inc)
The FDA approved a supplemental application for BLINCYTO (blinatumomab) submitted by Amgen, signaling an update to labeling and/or indicatio…
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FDA approval · 2019-04-18FDA Approved: BUSULFAN — Original Application (Armas Pharmaceuticals Inc.)
FDA approved a generic Busulfan from Armas Pharmaceuticals Inc. under ANDA210931, enabling a generic formulation.
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: Study of Palbociclib in MLL-rearranged Acute Leukemias [Phase 1, Phase 2]
A clinical trial investigating palbociclib in MLL-rearranged acute leukemias (AML and ALL) across Phase 1 and Phase 2 ongoing with currently…
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: ALL SCTped FORUM - Pharmacogenomic Study (add-on Study) [Phase 4]
Pharmacogenomic add-on study in Acute Lymphoblastic Leukemia is in Phase 4 and actively recruiting.
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CLINICAL_TRIALS trial_result · 2019-04-08Clinical Trial Update: CD19 hsCAR-T for Refractory/Relapsed CD19+ B-ALL Patients [Phase 2]
Phase 2 clinical trial update for CD19 hsCAR-T therapy in refractory/relapsed CD19+ B-ALL.
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CLINICAL_TRIALS trial_result · 2019-04-03Clinical Trial Update: Re-Induction Therapy for Relapsed Pediatric T-Cell Acute Lymphoblastic Leukemia or Lymphoma [Phase 2]
Phase 2 trial update on re-induction therapy for relapsed pediatric T-cell acute lymphoblastic leukemia or lymphoma; study terminated with p…
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CLINICAL_TRIALS trial_result · 2019-03-20Clinical Trial Update: Study of US-ATG-F to Prevent Chronic Graft Versus Host Disease (GVHD) [Phase 3]
A Phase 3 trial evaluating US-ATG-F to prevent chronic graft-versus-host disease in hematologic malignancy patients has completed with resul…
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CLINICAL_TRIALS trial_result · 2019-02-26Clinical Trial Update: Pilot Study Evaluating Safety & Efficacy of DCBT: NiCord® & UNM CBU to Patients With Hematological Malignancies [Phase 1, Phase 2]
A pilot Phase 1/2 study evaluating safety and efficacy of NiCord and UNM CBU in patients with various hematologic malignancies has completed…
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CLINICAL_TRIALS trial_result · 2019-02-19Clinical Trial Update: Erwinase for Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) (IND 104224) [Phase 1]
A Phase 1 trial of Erwinase for relapsed/refractory acute lymphoblastic leukemia, including patients with allergies to PEGylated or native E…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Chemotherapy With or Without Imatinib and/or Peripheral Stem Cell Transplant in Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial evaluating chemotherapy with or without imatinib and/or peripheral stem cell transplant in adults with acute lymphoblastic leu…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: SugarFACT - Sugar Requirements For African Children Trial [NA]
The SugarFACT trial evaluating sugar requirements for African children has been terminated, with conditions including hypoglycemia in non-di…
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CLINICAL_TRIALS trial_result · 2019-02-12Clinical Trial Update: Bridging Study to Eliminate Presence of MRD for Acute Leukemia Before HCT [Phase 2]
Phase 2 bridging study evaluating elimination of minimal residual disease before hematopoietic cell transplantation in acute leukemia; study…
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Propofol to Reduce the Incidence of Postanesthetic Emergence Agitation in Pediatric Patients Under General Anesthesia [NA]
This completed clinical trial evaluated whether propofol reduces postanesthetic emergence agitation in pediatric patients undergoing general…
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CLINICAL_TRIALS trial_result · 2019-01-25Clinical Trial Update: Clofarabine-cyclophosphamide as Salvage Therapy for Refractory and Relapsed Acute Lymphoblastic Leukemia (ALL) Adults [Phase 2]
A Phase 2 trial evaluating the combination of clofarabine and cyclophosphamide as salvage therapy for adults with refractory or relapsed acu…
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CLINICAL_TRIALS trial_result · 2019-01-25Clinical Trial Update: Yttrium-90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk AML, ALL, or MDS [Phase 1]
Phase 1 clinical trial evaluating Yttrium-90 anti-CD45 monoclonal antibody BC8 followed by donor stem cell transplant in patients with high-…
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CLINICAL_TRIALS trial_result · 2019-01-24Clinical Trial Update: Red Cell Transfusion Goals in Patients With Acute Leukemias [Phase 1]
Phase 1 trial completed evaluating red blood cell transfusion goals in patients with acute leukemias (acute lymphoblastic leukemia, acute my…
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CLINICAL_TRIALS trial_result · 2019-01-18Clinical Trial Update: Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell Transplantation [Phase 1]
Phase 1 trial evaluating inducible regulatory T cells (iTregs) in non-myeloablative sibling donor peripheral blood stem cell transplantation…
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FDA approval · 2019-01-18FDA Approved: CYCLOPHOSPHAMIDE — Original Application (Cipla USA Inc.)
The FDA approved Cipla USA Inc.'s original application for a generic cyclophosphamide product. This marks approval of a generic formulation …
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FDA approval · 2019-01-17FDA Approved: IMATINIB MESYLATE — Original Application (Ascend Laboratories, LLC)
FDA approved Ascend Laboratories' imatinib mesylate as an original application for a generic version of the cancer drug, for the same indica…
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FDA approval · 2019-01-17FDA Approved: IMATINIB MESYLATE — Original Application (Chartwell RX, LLC)
FDA approves an original ANDA for imatinib mesylate, granting Chartwell RX, LLC a generic version (ANDA 208429).
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CLINICAL_TRIALS trial_result · 2019-01-04Clinical Trial Update: Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies [Phase 2]
Phase 2 results from a study using donor umbilical cord blood stem cell transplants in patients with hematologic malignancies have been post…