Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-09-02Clinical Trial Update: A Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100) [Phase 1, Phase 2]
Phase 1/2 trial evaluating safety and activity of pegylated recombinant human arginase (BCT-100) in pediatric cancers; study completed.
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CLINICAL_TRIALS trial_result · 2022-08-31Clinical Trial Update: Genetically Modified T-Cell Therapy in Treating Patients With Advanced ROR1+ Malignancies [Phase 1]
Phase 1 trial update of a genetically modified T-cell therapy targeting ROR1 in advanced malignancies, with terminated status and posted res…
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CLINICAL_TRIALS trial_result · 2022-08-05Clinical Trial Update: HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic Malignancies [Phase 2]
Phase 2 clinical trial evaluating HLA-compatible related or unrelated donors with CD34+ enriched, T-cell depleted peripheral blood stem cell…
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CLINICAL_TRIALS trial_result · 2022-07-15Clinical Trial Update: Study of Efficacy and Safety of Reinfusion of Tisagenlecleucel in Pediatric and Young Adult Patients With Acute Lymphoblastic Leukemia (ALL) [Phase 2]
A Phase 2 trial evaluating reinfusion of tisagenlecleucel in pediatric and young adult patients with acute lymphoblastic leukemia has been t…
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CLINICAL_TRIALS trial_result · 2022-07-14Clinical Trial Update: Vyxeos(CPX-351) in Adults w R/R Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial of Vyxeos (CPX-351) in adults with relapsed or refractory acute lymphoblastic leukemia has completed and results were posted i…
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CLINICAL_TRIALS trial_result · 2022-07-13Clinical Trial Update: Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin in Treating Patients With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma [Phase 2]
Phase 2 trial evaluating a multi-agent regimen (etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin) for Acute Lymphoblastic L…
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CLINICAL_TRIALS research · 2022-07-12Clinical Trial Update: Safety Study of Gene Modified Donor T-cells Following Partially Mismatched Stem Cell Transplant [Phase 1, Phase 2]
A Phase 1/2 safety study evaluating gene-modified donor T-cells after partially mismatched stem cell transplantation in patients with leukem…
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CLINICAL_TRIALS trial_result · 2022-07-12Clinical Trial Update: Study of Gene Modified Donor T-cells Following TCR Alpha Beta Positive Depleted Stem Cell Transplant [Phase 1, Phase 2]
Clinical trial update for a phase 1/2 study evaluating gene-modified donor T-cells after TCR alpha beta–negative depleted stem cell transpla…
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FDA approval · 2022-06-21FDA Approved: IMATINIB MESYLATE — Original Application (Upsher-Smith Laboratories, LLC)
FDA approved an original application for imatinib mesylate (Upsher-Smith Laboratories) as a generic product. The approval supports its use f…
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CLINICAL_TRIALS trial_result · 2022-06-10Clinical Trial Update: A Clinical Study of SHP674 (Pegaspargase) in Participants With Newly Diagnosed, Untreated Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical study of SHP674 (Pegaspargase) in newly diagnosed, untreated acute lymphoblastic leukemia has completed with results posted…
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CLINICAL_TRIALS trial_result · 2022-05-27Clinical Trial Update: Phase II Study of Clofarabine in Pediatric Acute Lymphoblastic Leukemia (ALL) [Phase 2]
Phase II study of clofarabine in pediatric acute lymphoblastic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2022-05-25Clinical Trial Update: Laboratory Treated T Cells in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma, or Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating laboratory-treated T cells in relapsed or refractory B-cell malignancies and acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2022-05-24Clinical Trial Update: Sapanisertib in Treating Patients With Relapsed and/or Refractory Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial evaluating sapanisertib in adults with relapsed or refractory acute lymphoblastic leukemia; results were posted in Ma…
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CLINICAL_TRIALS trial_result · 2022-05-24Clinical Trial Update: Safety and Efficacy of ATIR101 as Adjunctive Treatment to Blood Stem Cell Transplantation From a Haploidentical Family Donor Compared to Post-transplant Cyclophosphamide in Patients With Blood Cancer [Phase 3]
Phase 3 trial updating safety and efficacy of ATIR101 as an adjunct to haploidentical stem cell transplantation versus post-transplant cyclo…
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CLINICAL_TRIALS trial_result · 2022-05-24Clinical Trial Update: International Collaborative Treatment Protocol For Children And Adolescents With Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 international collaborative treatment protocol for children and adolescents with acute lymphoblastic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2022-05-18Clinical Trial Update: Comparative Study of BFC and BuCy Conditioning Regimen for Allo-PBSCT in Acute B-cell ALL [Phase 4]
Clinical trial comparing BFC versus BuCy conditioning for allogeneic stem cell transplant in acute B-lymphoblastic leukemia; Phase 4, status…
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CLINICAL_TRIALS trial_result · 2022-05-02Clinical Trial Update: Ruxolitinib Phosphate or Dasatinib With Chemotherapy in Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 trial evaluating ruxolitinib phosphate or dasatinib with chemotherapy in relapsed or refractory Philadelphia chromosome-like acute…
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CLINICAL_TRIALS trial_result · 2022-04-25Clinical Trial Update: Evaluate the Efficacy and Safety of Rasburicase (Fasturtec®) in the Prevention and Treatment of Hyperuricemia in Pediatric Patients With Non-Hodgkin's Lymphoma and Acute Leukemia [Phase 4]
Phase 4 clinical trial evaluating rasburicase for prevention and treatment of hyperuricemia in pediatric patients with non-Hodgkin's lymphom…
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CLINICAL_TRIALS research · 2022-04-22Clinical Trial Update: Investigating the Effects of Hydroxyvitamin D3 on Multiple Sclerosis [Phase 4]
A Phase 4 clinical trial update investigates the effects of hydroxyvitamin D3 on multiple sclerosis and related conditions.
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: Stem Cell Transplantation From HLA Partially-Matched Related Donors for Patients With Hematologic Malignancies [Phase 3]
Phase 3 clinical trial update on stem cell transplantation from partially HLA-m matched related donors for hematologic malignancies; trial c…
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: First in Human Testing of Dose-escalation of SAR440234 in Patients With Acute Myeloid Leukemia, Acute Lymphoid Leukemia and Myelodysplastic Syndrome [Phase 1, Phase 2]
First-in-human dose-escalation study of SAR440234 in acute leukemia and myelodysplastic syndrome was terminated; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-04-06Clinical Trial Update: S1312, Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Leukemia [Phase 1]
Phase 1 trial evaluating S1312 (inotuzumab ozogamicin) with combination chemotherapy in adults with relapsed or refractory acute leukemias; …
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CLINICAL_TRIALS trial_result · 2022-03-28Clinical Trial Update: Safety and Efficiency of γδ T Cell Against Hematological Malignancies After Allo-HSCT [Phase 1, Phase 2]
This clinical trial evaluates the safety and efficacy of γδ T cell therapy after allogeneic hematopoietic stem cell transplantation in hemat…
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CLINICAL_TRIALS trial_result · 2022-03-24Clinical Trial Update: Study of Efficacy and Safety of Flumatinib Combined With Chemotherapy in Ph Positive ALL [Phase 3]
Phase 3 trial evaluating efficacy and safety of flumatinib in combination with chemotherapy for Philadelphia chromosome-positive acute lymph…
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CLINICAL_TRIALS trial_result · 2022-03-08Clinical Trial Update: A Study of the Safety and Effectiveness of Apixaban in Preventing Blood Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With Asparaginase [Phase 3]
Phase 3 trial evaluating safety and effectiveness of apixaban to prevent blood clots in children with leukemia and a central venous catheter…