Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-01-31Clinical Trial Update: Study Comparing Bivalirudin Versus Heparin in Neonatal and Pediatric ECMO [Phase 4]
A Phase 4 study comparing bivalirudin versus heparin in neonatal and pediatric patients on ECMO has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-01-31Clinical Trial Update: Tac, Mini-MTX, MMF Versus Tac, MTX for GVHD Prevention [Phase 3]
Phase 3 trial comparing Tacrolimus plus mini-methotrexate versus Tacrolimus plus methotrexate for graft-versus-host disease prevention has c…
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CLINICAL_TRIALS trial_result · 2023-01-25Clinical Trial Update: Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 trial evaluating Blinatumomab with either combination chemotherapy or Dasatinib, Prednisone, and Blinatumomab in older patients wi…
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CLINICAL_TRIALS trial_result · 2023-01-23Clinical Trial Update: Adoptive Immunotherapy in Relapsed Hematological Malignancy: Early GVHD Prophylaxis [Phase 2]
Phase 2 trial of adoptive immunotherapy in relapsed hematological malignancies with early GVHD prophylaxis has completed enrollment and post…
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CLINICAL_TRIALS trial_result · 2023-01-20Clinical Trial Update: Blinatumomab Maintenance Following Allogeneic Hematopoietic Cell Transplantation for Patients With Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 clinical trial evaluating blinatumomab maintenance after allogeneic stem cell transplantation in patients with acute lymphoblastic…
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CLINICAL_TRIALS trial_result · 2023-01-12Clinical Trial Update: South China Children Cancer Group - Relapsed-Acute Lymphoblastic Leukemia 2022 Protocol [Phase 4]
Clinical trial update for a Phase 4 study investigating arsenic trioxide in childhood acute lymphoblastic leukemia conducted by South China …
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FDA approval · 2023-01-09FDA Approved: CLOFARABINE — Supplemental Application (Mylan Institutional LLC)
FDA approved a supplemental application for clofarabine (CLOFARABINE) from Mylan Institutional LLC, expanding the regulatory approval for th…
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CLINICAL_TRIALS trial_result · 2023-01-04Clinical Trial Update: Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant [Phase 1, Phase 2]
A phase 1/2 safety study evaluating gene-modified donor T-cells after TCRαβ+ depleted stem cell transplant was terminated; results were post…
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FDA approval · 2022-12-22FDA Approved: ONCASPAR — Supplemental Application (Servier Pharmaceuticals LLC)
The FDA approved a supplemental application for ONCASPAR (pegaspargase) submitted by Servier Pharmaceuticals LLC.
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CLINICAL_TRIALS trial_result · 2022-12-06Clinical Trial Update: Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 clinical trial evaluating blinatumomab for younger patients with relapsed B-cell acute lymphoblastic leukemia.
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FDA approval · 2022-12-05FDA Approved: BLINCYTO — Supplemental Application (Amgen, Inc)
The FDA approved a supplemental application for BLINCYTO (blinatumomab) submitted by Amgen, expanding its regulatory scope.
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FDA approval · 2022-11-29FDA Approved: JYLAMVO — Original Application (SHORLA ONCOLOGY INC.)
FDA approved JYLAMVO (methotrexate) under an Original Application from SHORLA ONCOLOGY INC.
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CLINICAL_TRIALS trial_result · 2022-11-29Clinical Trial Update: Pyronaridine in Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 clinical trial update for pyronaridine in acute myeloid leukemia and acute lymphoblastic leukemia is in progress with unknown status…
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FDA approval · 2022-11-18FDA Approved: RYLAZE — Supplemental Application (Jazz Pharmaceuticals, Inc.)
The FDA approved Jazz Pharmaceuticals' supplemental application for RYLAZE (ASPARAGINASE ERWINIA CHRYSANTHEMI (RECOMBINANT)-RYWN). The appro…
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CLINICAL_TRIALS trial_result · 2022-11-14Clinical Trial Update: Efprezimod Alfa (CD24Fc, MK-7110) for the Prevention of Acute Graft Versus Host Disease (GVHD) Following Myeloablative Hematopoietic Stem Cell Transplantation (HSCT) (MK-7110-005) [Phase 3]
Phase 3 trial evaluating Efprezimod Alfa (CD24Fc, MK-7110) for prevention of acute graft-versus-host disease after myeloablative HSCT; study…
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CLINICAL_TRIALS trial_result · 2022-11-04Clinical Trial Update: Low-Intensity Chemotherapy and Blinatumomab in Treating Patients With Philadelphia Chromosome Negative Relapsed or Refractory Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial update on low-intensity chemotherapy combined with blinatumomab in Philadelphia chromosome–negative relapsed or refractory acu…
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CLINICAL_TRIALS trial_result · 2022-10-25Clinical Trial Update: Stem Cell Transplantation With NiCord® (Omidubicel) vs Standard UCB in Patients With Leukemia, Lymphoma, and MDS [Phase 3]
Phase 3 trial comparing NiCord (omidubicel) stem cell transplantation to standard umbilical cord blood in patients with hematologic malignan…
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CLINICAL_TRIALS trial_result · 2022-10-25Clinical Trial Update: Mitoxantrone and Clofarabine for Treatment of Recurrent NHL or Acute Leukemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating mitoxantrone with clofarabine for recurrent non-Hodgkin lymphoma or acute leukemia has completed.
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CLINICAL_TRIALS trial_result · 2022-10-13Clinical Trial Update: Cladribine Combined With G-CSF and Cytarabine as a Salvage Treatment in R/R ALL [Phase 2, Phase 3]
A phase 2/3 clinical trial investigates cladribine with G-CSF and cytarabine as salvage therapy for relapsed/refractory acute lymphoblastic …
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CLINICAL_TRIALS trial_result · 2022-10-12Clinical Trial Update: "Geriatric Assessment Adapted" Therapy for Ph- ALL Elderly Patients [Phase 2]
Phase 2 clinical trial evaluating a geriatric assessment adapted therapy for elderly patients with Philadelphia-negative acute lymphoblastic…
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CLINICAL_TRIALS trial_result · 2022-10-07Clinical Trial Update: Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow [Phase 2]
Phase 2 trial update on specialized blood cell transplants for cancers of the blood and bone marrow; study completed with results posted.
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FDA approval · 2022-10-03FDA Approved: CLOFARABINE — Original Application (Eugia US LLC)
FDA approved the original ANDA for clofarabine, manufactured by Eugia US LLC.
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CLINICAL_TRIALS trial_result · 2022-09-27Clinical Trial Update: Hyper-CVAD With Liposomal Vincristine in Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial update for Hyper-CVAD with liposomal vincristine in acute lymphoblastic leukemia is completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-09-21Clinical Trial Update: Fludarabine / Total Body Irradiation Regimen for ALLO HCT in Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial evaluating a fludarabine and total body irradiation regimen as conditioning for allogeneic hematopoietic cell transpl…
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CLINICAL_TRIALS trial_result · 2022-09-10Clinical Trial Update: SC-PEG Asparaginase vs. Oncaspar in Pediatric Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic Lymphoma [Phase 2]
This Phase 2 trial compares SC-PEG Asparaginase to Oncaspar in pediatric acute lymphoblastic leukemia and lymphoblastic lymphoma, with resul…