Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2018-06-04Clinical Trial Update: CART-19 FOR Relapsed/Refractory Acute Lymphoblastic Leukemia （ALL） [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating CART-19, a CD19-targeted CAR-T cell therapy, for relapsed or refractory acute lymphoblastic leukemia; …
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CLINICAL_TRIALS research · 2018-05-09Clinical Trial Update: Pentoxifylline In Pediatric Acute Lymphoblastic Leukemia During Induction [Phase 2, Phase 3]
This clinical trial update discusses the Phase 2/Phase 3 evaluation of pentoxifylline in pediatric patients undergoing induction therapy for…
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CLINICAL_TRIALS research · 2018-05-08Clinical Trial Update: ALL-Active: A Family-Based Lifestyle Program for Pediatric Acute Leukemia Patients [NA]
ALL-Active is a family-based lifestyle program for pediatric acute lymphoblastic leukemia patients in remission; this update notes the trial…
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CLINICAL_TRIALS research · 2018-04-11Clinical Trial Update: Refining and Testing the Diagnostic Accuracy of PAT-POPS
An update on a clinical trial evaluating the diagnostic accuracy of PAT-POPS for acute lymphoblastic leukemia in pediatric patients.
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CLINICAL_TRIALS research · 2017-12-06Clinical Trial Update: Antiminor Histocompatibility Complex (MiHA) T Cells for Patients With Relapsed Hematologic Malignancies Following Matched HSCT (Guided Lymphocyte Immunopeptide Derived Expansion) [Phase 1, Phase 2]
Phase 1/2 study investigating Antiminor Histocompatibility Complex (MiHA) T cells in patients with relapsed hematologic malignancies after m…
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CLINICAL_TRIALS research · 2017-11-08Clinical Trial Update: Observation of the Effect of Chemotherapy Combined With Tyrosinase Inhibitor on the Reactivation of CMV and EBV in Patients With Acute Lymphoblastic Leukemia
A clinical trial update examines the effect of a chemotherapy regimen combined with a tyrosinase inhibitor on reactivation of CMV and EBV in…
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CLINICAL_TRIALS research · 2017-08-29Clinical Trial Update: New Markers for Minimal Residual Disease in Acute Lymphoblastic Leukemia
A clinical trial update from Assiut University investigates new markers for detecting minimal residual disease in acute lymphoblastic leukem…
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CLINICAL_TRIALS research · 2017-07-28Clinical Trial Update: Study of Blood and Tissue Samples in Children With Newly Diagnosed Acute Lymphoblastic Leukemia
This clinical trial update describes a study collecting blood and tissue samples from children with newly diagnosed acute lymphoblastic leuk…
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CLINICAL_TRIALS research · 2017-06-20Clinical Trial Update: A Study of Anti-CD19 CAR-T Cell Immunotherapy for Refractory /Relapsed B Cell Malignancies [Phase 1, Phase 2]
This clinical trial update reports on a Phase 1/Phase 2 study of an anti-CD19 CAR-T cell therapy for refractory/relapsed B-cell malignancies…
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CLINICAL_TRIALS research · 2017-06-19Clinical Trial Update: Modified MRCUKALLⅫ/ECOGE2993 Regimen for ALL [Phase 2]
Phase 2 clinical trial update on a modified MRCUKALL XII/ECOG E2993 regimen for acute lymphoblastic leukemia.
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CLINICAL_TRIALS research · 2017-04-26Clinical Trial Update: DNA Analysis of Bone Marrow and Blood Samples From Young Patients With Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia
This completed clinical trial updates DNA analysis of bone marrow and blood samples from young patients with acute myeloid leukemia or acute…
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CLINICAL_TRIALS research · 2017-04-21Clinical Trial Update: ALL2008 Protocol for Childhood Acute Lymphoblastic Leukemia Intermittent Versus Continuous PEG Asparaginase [Phase 3]
Phase 3 pediatric trial comparing intermittent versus continuous PEG-asparaginase in childhood acute lymphoblastic leukemia has completed.
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CLINICAL_TRIALS research · 2017-03-16Clinical Trial Update: Competitive Transfer of αCD19-TCRz-CD28 and αCD19-TCRz-CD137 CAR-T Cells for B-cell Leukemia/Lymphoma [Phase 1, Phase 2]
This document describes a Phase 1/2 clinical trial evaluating competitive transfer of two αCD19-TCRz-CAR-T cell constructs (one with CD28 an…
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CLINICAL_TRIALS research · 2017-03-03Clinical Trial Update: Comparison Between Cyclophosphamide and Combination of Methotrexate + Calcineurin Inhibitor for GVHD Prophylaxis [Phase 3]
A Phase 3 trial comparing cyclophosphamide with methotrexate plus a calcineurin inhibitor for GVHD prophylaxis in patients with various hema…
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CLINICAL_TRIALS research · 2017-01-16Clinical Trial Update: Optimizing 6-mercaptopurine Therapy in Pediatric Acute Lymphoblastic Leukemia by Using Allopurinol [Phase 2]
Phase 2 clinical trial exploring optimization of 6-mercaptopurine therapy for pediatric acute lymphoblastic leukemia using allopurinol.
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CLINICAL_TRIALS research · 2016-12-15Clinical Trial Update: Design and Evaluation of Care Environment and Technology at Pediatric Radiotherapy
This clinical trial update from Umeå University reports on the design and evaluation of the care environment and technology used in pediatri…
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CLINICAL_TRIALS research · 2016-10-12Clinical Trial Update: Molecular Epidemiology of Childhood Leukemia (Aka The California Childhood Leukemia Study)
A completed status update for the California Childhood Leukemia Study, a molecular epidemiology study investigating childhood leukemia. The …
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CLINICAL_TRIALS research · 2016-09-30Clinical Trial Update: Malaysia-Singapore Acute Lymphoblastic Leukemia 2010 Study [Phase 4]
This entry reports a Phase 4 clinical trial update for a Malaysia-Singapore Acute Lymphoblastic Leukemia study; current status is not specif…
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CLINICAL_TRIALS research · 2016-08-22Clinical Trial Update: Effect of Enteral Docosahexaenoic Acid Administration in Children With Acute Lymphoblastic Leukemia [Phase 2]
This entry reports the completion of a Phase 2 trial evaluating enteral docosahexaenoic acid in children with acute lymphoblastic leukemia (…
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CLINICAL_TRIALS research · 2016-07-06Clinical Trial Update: Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia [Phase 2]
A completed Phase 2 clinical trial assessing combination chemotherapy in patients with untreated acute lymphoblastic leukemia.
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CLINICAL_TRIALS research · 2016-06-14Clinical Trial Update: Carfilzomib in Patients With Relapsed Acute Myeloid or Acute Lymphoblastic Leukemia [Phase 1]
This clinical trial update reports the completion of a Phase 1 study evaluating carfilzomib in patients with relapsed acute myeloid leukemia…
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CLINICAL_TRIALS research · 2016-05-17Clinical Trial Update: Studying DNA in Blood and Bone Marrow Samples From Young Patients With Acute Lymphoblastic Leukemia
This clinical trial update describes a study examining DNA in blood and bone marrow samples from young patients with acute lymphoblastic leu…
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CLINICAL_TRIALS research · 2016-05-17Clinical Trial Update: Laboratory Study of Lymphoblasts in Young Patients With High-Risk Acute Lymphoblastic Leukemia
A completed clinical trial registry entry describing a laboratory study of lymphoblasts in young patients with high-risk acute lymphoblastic…
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CLINICAL_TRIALS research · 2016-03-04Clinical Trial Update: Pharmacokinetics of Asparaginase and Antibody Formation in Interfant-06
This update reports on the pharmacokinetics of asparaginase and the development of anti-asparaginase antibodies in the Interfant-06 leukemia…
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CLINICAL_TRIALS research · 2016-02-17Clinical Trial Update: A 5 Day Course of Fludarabine and Cytarabine Followed by Full Intensity Allogeneic Stem Cell Transplantation (FA5-Bucy) in Treating Patients With High-risk, Recurrent or Refractory Acute Leukemia and Advanced Myelodysplastic Syndrome
A clinical trial update describes a five-day course of fludarabine and cytarabine followed by full-intensity allogeneic stem cell transplant…