Exacerbation of Chronic Obstructive Pulmonary Disease
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Atorvastatin Effect on Reduction of COPD Exacerbations [Phase 4]
Phase 4 trial evaluating atorvastatin for reducing COPD exacerbations; study status is active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Monitoring of the End-tidal Carbon Dioxide (EtCO2) as a Severity Criterion in COPD Exacerbations
This clinical trial is evaluating whether monitoring end-tidal CO2 can help gauge severity in COPD exacerbations and is currently recruiting…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Using Multiomics to Define Mechanisms of Rhinovirus-induced Chronic Obstructive Pulmonary Disease Exacerbations to Develop Novel Therapies and Therapeutic Targets
Clinical trial update from Imperial College London focuses on using multiomics to define how rhinovirus triggers COPD exacerbations and to i…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Assessing Optimal Inhaler Strategies During Acute Exacerbations of COPD (AECOPDs) Using Oscillometry
The clinical trial evaluating optimal inhaler strategies during acute COPD exacerbations using oscillometry has completed. It was sponsored …
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Effect of Pulmonary Rehabilitation in Females With Acute Exacerbation of COPD Induced by Biomass Fuel Smoke [NA]
This ClinicalTrials.gov entry outlines a study evaluating whether pulmonary rehabilitation benefits women with acute exacerbation of COPD ca…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Decision-making and Optimization of Ventilatory Support for AECOPD Patients
This ClinicalTrials.gov update outlines plans to study decision-making and optimization of ventilatory support for patients with acute exace…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Effect of Low-Dose Versus High-Dose Alpha-Lipoic Acid on Oxidative Stress, Inflammation, and Clinical Outcomes in Acute Exacerbations of Chronic Obstructive Pulmonary Disease [Phase 3]
Phase 3 clinical trial evaluating low-dose versus high-dose alpha-lipoic acid for oxidative stress, inflammation, and clinical outcomes in a…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Evaluation of High Dose Prednisolone Pharmacokinetics in the Acute and Chronic Setting
Clinical trial from Imperial College London evaluating the pharmacokinetics of high-dose prednisolone in acute and chronic inflammatory sett…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Home Oscillatory Positive Expiratory Pressure - Aerobic Exercise Rehabilitation Study [NA]
Clinical trial investigating home oscillatory positive expiratory pressure combined with aerobic exercise rehabilitation for chronic obstruc…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Comparing Hydrocortisone and Prednisolone for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) [Phase 4]
A Phase 4 clinical trial comparing hydrocortisone to prednisolone for acute exacerbation of chronic obstructive pulmonary disease is current…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Effectiveness of Xuanfei Jiangzhuo Decoction for Influenza-Induced AECOPD
A clinical trial sponsored by Tianjin Medical University is evaluating the effectiveness of Xuanfei Jiangzhuo Decoction for influenza-induce…
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: Comparing Mortality for Low vs High Peripheral Oxygen Saturation in COPD-patients With Acute Exacerbation [Phase 4]
Phase 4 trial in chronic obstructive pulmonary disease with acute exacerbation evaluating mortality differences between low versus high peri…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Clinical Study on Guben Kechuan Granules Promoting Disease Recovery by Regulating Immune-Inflammatory Dysregulation in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease During the Peri-Discharge Period [NA]
Clinical trial evaluating Guben Kechuan Granules to promote recovery in patients with acute exacerbation of chronic obstructive pulmonary di…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Emotional-distress-based Integrated Care Programme in Patients With an Acute Exacerbation of COPD [NA]
The document announces that the University of Zurich is recruiting for a study evaluating an emotional-distress-based integrated care progra…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Lower Respiratory Tract Infections Managed in Primary Care in France
A completed French clinical trial evaluated how lower respiratory tract infections, including community-acquired pneumonia and COPD exacerba…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD [Phase 3]
A Phase 3 study comparing the efficacy, safety and tolerability of a fixed-dose triple combination CHF 5993 versus a fixed-dose dual combina…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: A Repeat Ascending Dosing Study of the Safety and Clinical Activity of R-3750 in Patients With Mild to Moderate COPD [Phase 1]
Phase 1 repeat ascending dose trial to evaluate the safety and preliminary activity of R-3750 in adults with mild-to-moderate COPD, includin…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: The REVIVE Pivotal Study [NA]
The REVIVE pivotal study sponsored by Ryme Medical, Inc. is currently not yet recruiting for COPD and COPD exacerbations.
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Personalized Prediction Strategy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease
This clinical trial update describes a personalized prediction strategy for acute exacerbations of chronic obstructive pulmonary disease (AE…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: REal-time Data Monitoring for Shared Adaptive, Multi-domain and Personalised Prediction and Decision Making for Long-term Pulmonary Care Ecosystems (RE-SAMPLE)
Update on the RE-SAMPLE clinical trial for real-time data monitoring in long-term pulmonary care, with the study now completed.
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Ultrasound of the Diaphragm Excursion Ratio as Physiological Biomarker in Acute Exacerbations of Chronic Obstructive Pulmonary Disease
This clinical trial is evaluating diaphragmatic excursion ratio by ultrasound as a physiological biomarker during acute exacerbations of chr…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Outcomes of Once-Daily ICS/LABA/LAMA + PRN Respiratory Therapy Treatments in Hospitalized Patients With COPD Exacerbations [Phase 4]
Phase 4 trial evaluating outcomes of once-daily triple inhaled therapy (ICS/LABA/LAMA) plus PRN respiratory therapy in hospitalized COPD pat…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Laying the Foundation for Building a Resilient KPNC Community in the Face of Worsening Air Quality Due to Wildfire Smoke [NA]
A Kaiser Permanente clinical trial entry describes an ongoing study to strengthen resilience against worsening air quality from wildfire smo…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Inhaler Trainer Efficacy Study [NA]
A clinical trial update indicates recruitment for a study evaluating an inhaler trainer device for asthma and chronic obstructive pulmonary …
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Intravenous Alpha-1 Antitrypsin for Hospitalized Patients With COPD Exacerbations (AECOPD Study) [Phase 2]
Phase 2 study evaluating intravenous alpha-1 antitrypsin in hospitalized patients with COPD exacerbations; the trial status is not yet recru…