Exacerbation of Chronic Obstructive Pulmonary Disease
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Atorvastatin Effect on Reduction of COPD Exacerbations [Phase 4]
Phase 4 trial evaluating atorvastatin for reducing COPD exacerbations; study status is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Assessing Optimal Inhaler Strategies During Acute Exacerbations of COPD (AECOPDs) Using Oscillometry
The clinical trial evaluating optimal inhaler strategies during acute COPD exacerbations using oscillometry has completed. It was sponsored …
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: Comparing Mortality for Low vs High Peripheral Oxygen Saturation in COPD-patients With Acute Exacerbation [Phase 4]
Phase 4 trial in chronic obstructive pulmonary disease with acute exacerbation evaluating mortality differences between low versus high peri…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Lower Respiratory Tract Infections Managed in Primary Care in France
A completed French clinical trial evaluated how lower respiratory tract infections, including community-acquired pneumonia and COPD exacerba…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD [Phase 3]
A Phase 3 study comparing the efficacy, safety and tolerability of a fixed-dose triple combination CHF 5993 versus a fixed-dose dual combina…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: REal-time Data Monitoring for Shared Adaptive, Multi-domain and Personalised Prediction and Decision Making for Long-term Pulmonary Care Ecosystems (RE-SAMPLE)
Update on the RE-SAMPLE clinical trial for real-time data monitoring in long-term pulmonary care, with the study now completed.
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Outcomes of Once-Daily ICS/LABA/LAMA + PRN Respiratory Therapy Treatments in Hospitalized Patients With COPD Exacerbations [Phase 4]
Phase 4 trial evaluating outcomes of once-daily triple inhaled therapy (ICS/LABA/LAMA) plus PRN respiratory therapy in hospitalized COPD pat…
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: Effects of High Flow Nasal Cannula on Sputum Clearance in Acute Exacerbation of Chronic Obstructive Pulmonary Disease [NA]
A clinical trial evaluating high flow nasal cannula for sputum clearance in acute exacerbation of chronic obstructive pulmonary disease has …
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: ProAir Digihaler in COPD Disease Management: A Real World Study
Real-world study results for ProAir Digihaler in COPD disease management are reported; the trial (NCT04821869) is completed and results were…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Reduction of Corticosteroid Use in Outpatient Treatment of Exacerbated COPD [NA]
A clinical trial evaluating reduction of corticosteroid use in outpatient treatment of COPD exacerbations has been terminated. No results ar…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Once Daily Long-Acting Muscarinic Antagonists Administered in the Evening for Prevention of Chronic Obstructive Pulmonary Disease Exacerbations Requiring Hospitalization or Death from Any Cause [Phase 4]
A Phase 4 clinical trial evaluating once-daily long-acting muscarinic antagonists for preventing COPD exacerbations requiring hospitalizatio…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Comparison Between Levofloxacin and Prulifloxacin, in Internal Medicine Patients With Acute Exacerbation of COPD [Phase 4]
A Phase 4 study comparing levofloxacin and prulifloxacin in patients with acute exacerbation of COPD; the trial has completed and results ha…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: AECOPD and Nutritional Supplementation in COPD [NA]
A completed clinical trial in chronic obstructive pulmonary disease evaluating nutritional supplementation for acute exacerbations; the prov…
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CLINICAL_TRIALS trial_result · 2025-01-09Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Sitafloxacin in Adult Subjects With Acute Exacerbation of Chronic Obstructive Pulmonary Disease [Phase 4]
Phase 4 clinical trial evaluating the efficacy and safety of Sitafloxacin in adults with acute exacerbation of chronic obstructive pulmonary…
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPD [Phase 3]
Phase 3 clinical trial evaluating the effectiveness of low-dose theophylline for biomass-associated chronic obstructive pulmonary disease ha…
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Treatment Efficacy of Systemic Corticosteroids in AECOPD Patients With Higher Blood Eosinophil Levels [Phase 4]
A Phase 4 clinical trial evaluating the efficacy of systemic corticosteroids in acute COPD exacerbations among patients with higher blood eo…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Study of Physiological Signals During and After COPD Exacerbations [NA]
The document reports on a completed clinical study from Biosency examining physiological signals in patients with COPD during and after exac…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: CRP, Procalcitonin and Pro-BNP as Diagnostic and Prognostic Markers in AECOPD
The completed trial evaluated inflammatory and cardiac biomarkers (CRP, procalcitonin, and pro-BNP) for diagnosing and prognosticating acute…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: COPD Exacerbation Blood and Urine Biomarkers Study
A clinical trial evaluating blood and urine biomarkers in chronic obstructive pulmonary disease, including acute exacerbations and alpha-1 a…
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CLINICAL_TRIALS trial_result · 2021-05-10Clinical Trial Update: Combination Antibiotic Therapy Compared to Monotherapy in the Treatment of Acute COPD [Phase 2, Phase 3]
A phase 2/3 trial assessing combination antibiotic therapy versus monotherapy for acute COPD exacerbation has been completed.
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CLINICAL_TRIALS trial_result · 2018-11-16Clinical Trial Update: Home Non Invasive Ventilation (NIV) Treatment for COPD-patients After a NIV-treated Exacerbation [Phase 4]
Phase 4 clinical trial update on home noninvasive ventilation for COPD patients after an NIV-treated exacerbation.
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CLINICAL_TRIALS trial_result · 2018-05-29Clinical Trial Update: Change in Breathing Pattern on Non-invasive Ventilation of COPD Patients Under Home Mechanical Ventilation
A clinical trial investigating changes in breathing patterns in COPD patients using home non-invasive ventilation has completed.
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CLINICAL_TRIALS trial_result · 2018-05-22Clinical Trial Update: Glucose Control During Glucocorticoid Therapy in Acute Exacerbation of Chronic Obstructive Pulmonary Disease [Phase 4]
Phase 4 study evaluating glucose control during glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease has c…
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CLINICAL_TRIALS trial_result · 2017-08-01Clinical Trial Update: Oral Prednisolone in Severe Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) [Phase 3]
Phase 3 study evaluating oral prednisolone for severe acute exacerbation of chronic obstructive pulmonary disease has completed.
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: nCD64 vs. Neutrophil/Lymphocyte Ratio for Predicting In-hospital Outcome in AE-COPD
This completed clinical trial (NCT03146611) evaluated whether nCD64 or the neutrophil/lymphocyte ratio better predicts in-hospital outcomes …