Exacerbation of Chronic Obstructive Pulmonary Disease
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: An Antibiotic Protocol Guided by a Multimodal Approach in AECOPD With Pneumonia in Intensive Care [NA]
A recruiting clinical trial evaluating a multimodal antibiotic protocol to reduce antibiotic exposure in ICU patients with COPD exacerbation…
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: Effects of High Flow Nasal Cannula on Sputum Clearance in Acute Exacerbation of Chronic Obstructive Pulmonary Disease [NA]
A clinical trial evaluating high flow nasal cannula for sputum clearance in acute exacerbation of chronic obstructive pulmonary disease has …
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: Value of Volume Oxygenation Index to Detect Early Failure of Non-invasive Ventilation in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
This clinical trial update assesses whether the VOX Oxygenation Index can detect early NIV failure in acute exacerbation of COPD. The study …
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: ProAir Digihaler in COPD Disease Management: A Real World Study
Real-world study results for ProAir Digihaler in COPD disease management are reported; the trial (NCT04821869) is completed and results were…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Efficacy Of Inpatient Pulmonary Rehabilitation Program In Elderly Patients With Acute Exacerbation Of COPD [NA]
ClinicalTrials.gov entry evaluating the efficacy of an inpatient pulmonary rehabilitation program for elderly patients with acute exacerbati…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Standard vs Targeted Oxygen Therapy Prehospital for Chronic Obstructive Pulmonary Disease [Phase 4]
This Phase 4 trial compares standard oxygen therapy to targeted oxygen therapy administered prehospital for COPD exacerbations and is curren…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: The Reducing REVISITS Study: A Cluster RCT [NA]
The Reducing REVISITS study is a cluster randomized trial that is currently recruiting to reduce hospital revisits among patients with chron…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Predicting Acute Exacerbations of COPD Using Wearable Devices and Remote Monitoring Technology With AI/ML Models
A McGill University Health Centre-led study protocol is evaluating whether wearable devices and remote AI/ML monitoring can predict acute CO…
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: Safety, PK and PD Relationships of RLS-0071 in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease [Phase 2]
Clinical Trial Update describing safety, pharmacokinetics and pharmacodynamics relationships of RLS-0071 in patients with acute exacerbation…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: The Use of Medical Devices to Monitor Chronic Obstructive Pulmonary Disease Patients Study BREATH-TRACHER 2
The BREATH-TRACHER 2 study, which assesses the use of medical devices to monitor COPD patients, is currently enrolling by invitation.
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Reduction of Corticosteroid Use in Outpatient Treatment of Exacerbated COPD [NA]
A clinical trial evaluating reduction of corticosteroid use in outpatient treatment of COPD exacerbations has been terminated. No results ar…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Once Daily Long-Acting Muscarinic Antagonists Administered in the Evening for Prevention of Chronic Obstructive Pulmonary Disease Exacerbations Requiring Hospitalization or Death from Any Cause [Phase 4]
A Phase 4 clinical trial evaluating once-daily long-acting muscarinic antagonists for preventing COPD exacerbations requiring hospitalizatio…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Comparison Between Levofloxacin and Prulifloxacin, in Internal Medicine Patients With Acute Exacerbation of COPD [Phase 4]
A Phase 4 study comparing levofloxacin and prulifloxacin in patients with acute exacerbation of COPD; the trial has completed and results ha…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: AECOPD and Nutritional Supplementation in COPD [NA]
A completed clinical trial in chronic obstructive pulmonary disease evaluating nutritional supplementation for acute exacerbations; the prov…
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CLINICAL_TRIALS research · 2025-01-16Clinical Trial Update: MxA and CRP-Guided Use of Antimicrobial Agents for AECOPD [NA]
Clinical trial update on using MxA and CRP levels to guide antimicrobial therapy in acute exacerbations of COPD.
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CLINICAL_TRIALS trial_result · 2025-01-09Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Sitafloxacin in Adult Subjects With Acute Exacerbation of Chronic Obstructive Pulmonary Disease [Phase 4]
Phase 4 clinical trial evaluating the efficacy and safety of Sitafloxacin in adults with acute exacerbation of chronic obstructive pulmonary…
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CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: Study to Evaluate the Clinical Value and Safety of Xiyanping Injection in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease(COPD) Based on Real-world Clinical Data
This clinical trial protocol evaluates the clinical value and safety of Xiyanping Injection for treating acute exacerbations of chronic obst…
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Nasal High-Flow in COPD [NA]
Clinical trial update on nasal high-flow therapy for COPD exacerbations; the study is currently recruiting.
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CLINICAL_TRIALS research · 2024-11-18Clinical Trial Update: Impact of HI-NPPV Vs LI-NPPV on Tolerance Among AECOPD Patients [NA]
A clinical trial is evaluating tolerance to high-intensity versus low-intensity noninvasive positive-pressure ventilation in acute exacerbat…
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Predictors of Acute Exacerbation in Patients With COPD - an Observational Study
An observational study evaluating predictors of acute exacerbations in patients with chronic obstructive pulmonary disease (COPD).
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPD [Phase 3]
Phase 3 clinical trial evaluating the effectiveness of low-dose theophylline for biomass-associated chronic obstructive pulmonary disease ha…
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Treatment Efficacy of Systemic Corticosteroids in AECOPD Patients With Higher Blood Eosinophil Levels [Phase 4]
A Phase 4 clinical trial evaluating the efficacy of systemic corticosteroids in acute COPD exacerbations among patients with higher blood eo…
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Effects of Blocking TSLP on Airway Inflammation and the Epithelial Immune-response to Exacerbation Triggers in Patients With COPD [Phase 2]
This Phase 2 trial in COPD patients investigates blocking thymic stromal lymphopoietin (TSLP) to reduce airway inflammation and modify epith…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Study of Physiological Signals During and After COPD Exacerbations [NA]
The document reports on a completed clinical study from Biosency examining physiological signals in patients with COPD during and after exac…
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CLINICAL_TRIALS research · 2024-08-05Clinical Trial Update: CO2 Removal in Severe Acute exacerbatIons of Chronic Obstructive Lung Diseases [NA]
A clinical trial evaluating CO2 removal in severe acute exacerbations of chronic obstructive pulmonary disease is active but not recruiting.