Clinical Trial Update: Non-Invasive Focused Ultrasound (FUS) With Oral Panobinostat in Children With Progressive Diffuse Midline Glioma (DMG) [Phase 1]

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Summary

A Phase 1 trial evaluating non-invasive focused ultrasound in combination with oral panobinostat for children with progressive diffuse midline glioma has been t…

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Diseases / indications

• Diffuse Intrinsic Pontine Glioma
• Diffuse Midline Glioma H3 K27-altered
• Diffuse Pontine and Thalamic Gliomas

Drugs mentioned

• Panobinostat (Panobinostat)

Snippet

Sponsor: Columbia University | Conditions: Diffuse Intrinsic Pontine Glioma, Diffuse Pontine and Thalamic Gliomas | Phase 1 | Status: TERMINATED | Results posted: 2025-06-08