X-linked Hypophosphatemia
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Calcitriol Monotherapy for X-Linked Hypophosphatemia [EARLY_Phase 1]
The document reports an EARLY_PHASE1 trial of Calcitriol as monotherapy for X-linked hypophosphatemia with status ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Burosumab in Patients Less Than 1 Year of Age [Phase 1, Phase 2]
This trial evaluated Burosumab in infants under 1 year with X-linked hypophosphatemia to assess safety, tolerability, pharmacokinetics and e…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: Study to Assess the Safety, Pharmacokinetics and Efficacy of KRN23 in Pediatric Chinese Patients With XLH [Phase 4]
A Phase 4 study evaluating the safety, pharmacokinetics, and efficacy of KRN23 in pediatric Chinese patients with X-linked hypophosphatemia …
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: Study to Assess the Safety, Pharmacokinetics and Efficacy of KRN23 in Adult Chinese Patients With XLH [Phase 4]
A Phase 4 trial evaluated the safety, pharmacokinetics, and efficacy of KRN23 (burosumab) in adult Chinese patients with X-linked hypophosph…
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CLINICAL_TRIALS trial_result · 2024-06-17Clinical Trial Update: A Study of KRN23 in X-linked Hypophosphatemia [Phase 1]
An update on Kyowa Kirin's Phase 1 study of KRN23 for X-linked Hypophosphatemia, noting that the trial has completed.
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CLINICAL_TRIALS trial_result · 2023-08-24Clinical Trial Update: Examining the Effect of Burosumab on Muscle Function [Phase 4]
Phase 4 clinical trial assessing the effect of burosumab on muscle function in X-linked hypophosphatemia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-05-03Clinical Trial Update: Anti-FGF23 (Burosumab) in Adult Patients With XLH [Phase 3]
Phase 3 trial update for burosumab in adults with X-linked Hypophosphatemia (XLH) has been completed.
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CLINICAL_TRIALS trial_result · 2022-05-20Clinical Trial Update: Study of the Anti-FGF23 Antibody, Burosumab, in Adults With XLH [Phase 3]
Phase 3 trial update for burosumab in adults with X-linked hypophosphatemia has completed.
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CLINICAL_TRIALS trial_result · 2021-05-05Clinical Trial Update: Prevention of Spontaneous Dental Abscesses in Children With X-linked Hypophosphatemia : a RCT [Phase 3]
Phase 3 randomized trial assessing prevention of spontaneous dental abscesses in children with X-linked hypophosphatemia (XLH).
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CLINICAL_TRIALS trial_result · 2021-02-17Clinical Trial Update: An Extension Study of KRN23 in Adults With X-Linked Hypophosphatemia [Phase 1, Phase 2]
An extension study of KRN23 (burosumab) in adults with X-linked hypophosphatemia has completed Phase 1/Phase 2, with results posted in Febru…
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CLINICAL_TRIALS trial_result · 2021-02-05Clinical Trial Update: Study of KRN23 in Adults With X-linked Hypophosphatemia (XLH) [Phase 3]
Phase 3 study of KRN23 (burosumab) in adults with X-linked hypophosphatemia has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2020-10-26Clinical Trial Update: A Repeated Study of KRN23 in Adults With X-Linked Hypophosphatemia [Phase 1, Phase 2]
A Phase 1/Phase 2 study of KRN23 in adults with X-linked hypophosphatemia has completed, and results were posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-06-05Clinical Trial Update: Burosumab in Children and Adolescents With X-linked Hypophosphatemia [Phase 4]
Phase 4 clinical trial update for burosumab in children and adolescents with X-linked hypophosphatemia (XLH).
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CLINICAL_TRIALS trial_result · 2019-12-16Clinical Trial Update: Long-Term Extension Study of KRN23 in Adult Subjects With X-Linked Hypophosphatemia (XLH) [Phase 2]
Phase 2 long-term extension trial of KRN23 (burosumab) in adults with X-Linked Hypophosphatemia has completed; results were posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-05-22Clinical Trial Update: Study of KRN23 (Burosumab), a Recombinant Fully Human Monoclonal Antibody Against Fibroblast Growth Factor 23 (FGF23), in Pediatric Subjects With X-linked Hypophosphatemia (XLH) [Phase 2]
Phase 2 study of burosumab (KRN23) in pediatric X-linked hypophosphatemia completed; results posted evaluating safety and efficacy.
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CLINICAL_TRIALS trial_result · 2019-04-11Clinical Trial Update: Efficacy and Safety of Burosumab Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients With XLH [Phase 3]
Phase 3 trial comparing burosumab to oral phosphate and active vitamin D in pediatric patients with X-linked hypophosphatemia; results asses…
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CLINICAL_TRIALS trial_result · 2018-09-25Clinical Trial Update: Open Label Study of KRN23 on Osteomalacia in Adults With X-linked Hypophosphatemia (XLH) [Phase 3]
Open-label Phase 3 study evaluating KRN23 for osteomalacia in adults with X-linked hypophosphatemia completed; results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: Study of the Safety, Pharmacodynamics (PD) and Efficacy of KRN23 in Children From 1 to 4 Years Old With X-linked Hypophosphatemia (XLH) [Phase 2]
Phase 2 study evaluating safety, pharmacodynamics, and efficacy of KRN23 in children aged 1 to 4 with X-linked hypophosphatemia; the trial i…
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Calcitonin for Treating X-linked Hypophosphatemia [NA]
A Yale University-sponsored clinical trial evaluating calcitonin for the treatment of X-linked hypophosphatemia has completed and posted res…
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: A Study of KRN23 in Subjects With X-linked Hypophosphatemic Rickets/Osteomalacia [Phase 1]
Phase 1 study of KRN23 in X-linked hypophosphatemia with osteomalacia has completed.