Wilms Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Study of Kidney Tumors in Younger Patients
The Children's Oncology Group study of kidney tumors in younger patients is currently active but not recruiting. It covers multiple pediatri…
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CLINICAL_TRIALS trial_result · 2025-03-04Clinical Trial Update: Nephrogreen. Appearances of Exvivo Renal Tumours Under Near-infrared [NA]
This clinical trial update reports on Nephrogreen, evaluating ex vivo appearances of renal tumors under near-infrared light; the study (NCT0…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Accurate Diagnosis and Grading of Pediatric Solid Tumors Based on Pathological Large Models
A clinical trial from Xinhua Hospital and Shanghai Jiao Tong University aims to improve diagnosis and grading of pediatric solid tumors usin…
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Intensity-Modulated Radiation Therapy in Treating Younger Patients With Lung Metastases [NA]
Clinical trial update indicates completion of a study evaluating intensity-modulated radiation therapy in younger patients with lung metasta…
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CLINICAL_TRIALS research · 2025-01-30Clinical Trial Update: International PPB/DICER1 Registry
An international registry to collect data on tumors associated with DICER1 syndrome, including Pleuropulmonary Blastoma and related tumors, …
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors [Phase 2]
Phase 2 trial evaluating neoadjuvant dual checkpoint inhibition with cryoablation in relapsed/refractory pediatric solid tumors has complete…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors [Phase 1]
Phase 1 trial completion evaluating MR-guided High Intensity Focused Ultrasound (HIFU) for relapsed or refractory pediatric solid tumors, in…
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CLINICAL_TRIALS withdrawal · 2025-01-01Clinical Trial Update: A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid Tumors [Phase 2]
A Phase 2 pilot study evaluating Thermodox in combination with MR-HIFU for relapsed solid tumors has been withdrawn.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 update on erdafitinib for FGFR-mutant relapsed or refractory pediatric cancers enrolled in the Pediatric MATCH trial; results were p…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 Pediatric MATCH trial evaluating samotolisib in pediatric patients with relapsed or refractory tumors harboring TSC or PI3K/mTOR mut…
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Study of Genistein in Pediatric Oncology Patients (UVA-Gen001) [Phase 2]
Phase 2 pediatric trial of Genistein for various cancers was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial) [Phase 2]
A pediatric MATCH phase 2 trial assessed olaparib in children with relapsed or refractory advanced solid tumors or non-Hodgkin lymphoma carr…
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CLINICAL_TRIALS trial_result · 2024-04-24Clinical Trial Update: Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating palbociclib in relapsed or refractory pediatric tumors with activating alterations in cell cycle ge…
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CLINICAL_TRIALS trial_result · 2024-04-05Clinical Trial Update: Molecular-Guided Therapy for Childhood Cancer [NA]
A completed clinical trial evaluating molecular-guided therapy for several childhood cancers, with results posted in April 2024.
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CLINICAL_TRIALS trial_result · 2022-11-28Clinical Trial Update: Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors [Phase 2]
A Phase 2 clinical trial evaluating cabozantinib-s-maleate in pediatric patients with recurrent, refractory, or newly diagnosed sarcomas, Wi…
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CLINICAL_TRIALS trial_result · 2021-04-30Clinical Trial Update: Stereotactic Body Radiotherapy (SBRT) for Pulmonary Metastases in Ewing Sarcoma, Rhabdomyosarcoma, and Wilms Tumors [Phase 1, Phase 2]
Phase 1/2 trial evaluating stereotactic body radiotherapy (SBRT) for pulmonary metastases in several pediatric and young adult sarcoma-relat…
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FDA approval · 2021-01-14FDA Approved: VINCRISTINE SULFATE — Supplemental Application (Hospira, Inc.)
The FDA approved a supplemental application filed by Hospira for vincristine sulfate, a generic vincristine product.
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CLINICAL_TRIALS trial_result · 2019-08-29Clinical Trial Update: Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma [Phase 2]
Phase 2 trial update for Lorvotuzumab Mertansine in several relapsed/refractory pediatric solid tumors; study completed with results posted …
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FDA approval · 2019-05-20FDA Approved: DACTINOMYCIN — Original Application (XGen Pharmaceuticals DJB, Inc.)
FDA approved the original (ANDA) application for Dactinomycin from XGen Pharmaceuticals DJB, Inc., establishing a generic version of this ch…
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CLINICAL_TRIALS trial_result · 2019-03-27Clinical Trial Update: Combination Therapy of Anthracyclines for Children With Nephroblastoma [Phase 4]
A Phase 4 clinical trial evaluating a combination chemotherapy regimen containing anthracyclines for nephroblastoma (Wilms tumor) in childre…
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CLINICAL_TRIALS trial_result · 2019-03-05Clinical Trial Update: Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor [Phase 3]
A Phase 3 trial evaluating combination chemotherapy and surgery for Wilms tumor in children, including cases associated with Beckwith-Wiedem…
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CLINICAL_TRIALS trial_result · 2019-03-05Clinical Trial Update: Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor [Phase 3]
A Phase 3 clinical trial on combined chemotherapy and surgery for Wilms tumor in young patients has been completed, with posted results.
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CLINICAL_TRIALS trial_result · 2018-10-31Clinical Trial Update: Liposomal Vincristine for Pediatric and Adolescent Patients With Relapsed Malignancies [Phase 2]
Phase 2 trial evaluating liposomal vincristine in pediatric and adolescent patients with relapsed malignancies has completed.
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CLINICAL_TRIALS trial_result · 2018-03-21Clinical Trial Update: HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors [Phase 1]
This update reports the completion of a Phase 1 clinical trial evaluating HSV-1716 in patients with non-CNS solid tumors, including rhabdomy…
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FDA approval · 2017-11-09FDA Approved: DACTINOMYCIN — Original Application (Eugia US LLC)
FDA approved the original ANDA for dactinomycin (generic) to Eugia US LLC, enabling generic manufacturing and distribution of this anticance…