Wilms Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Treatment of Newly Diagnosed Patient's With Wilm's Tumor Requiring Abdominal Radiation Delivered With Proton Beam Irradiation [Phase 2]
Phase 2 trial evaluating abdominal radiation with proton beam therapy for newly diagnosed Wilms tumor; recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Pencil Beam Scanning in Patients With Renal Tumors [EARLY_Phase 1]
An early-phase trial evaluating pencil beam scanning radiotherapy in renal tumors (including Wilms tumor) is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR) [Phase 1]
Phase 1 clinical trial update for a B7-H3–targeted autologous CAR-T cell therapy (3CAR) in pediatric solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies [Phase 1]
Phase 1 trial at New York Medical College evaluating vorinostat in combination with chemotherapy for relapsed/refractory solid tumors and CN…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial) [Phase 2]
Phase 2 update from the Pediatric MATCH trial describes targeted therapies matched to tumor genetics in pediatric patients with relapsed or …
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors [Phase 1]
Phase 1 trial evaluating an IL-15/IL-21 armored GPC3-targeted CAR-T cell therapy for pediatric solid tumors is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Metronomic Chemotherapy in Wilms Tumor (MetroWilms-1906) [Phase 1, Phase 2]
A clinical trial update for MetroWilms-1906 evaluating metronomic chemotherapy in Wilms Tumor, currently recruiting for Phase 1/2.
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors [Phase 1]
Phase 1 trial evaluating IL-15 armored glypican-3–specific CAR-T cells for solid tumors, including hepatocellular carcinoma and several pedi…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT) [Phase 3]
A Phase 3 study is evaluating risk-factor–driven treatment for children with favorable-histology Wilms tumors. The trial is currently recrui…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Project: Every Child for Younger Patients With Cancer
Clinical trial update from the Children's Oncology Group shows that the multi-indication pediatric trial 'Project: Every Child for Younger P…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT [Phase 2]
This clinical trial update indicates a Phase 2 study by the Children's Oncology Group evaluating combination chemotherapy for newly diagnose…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells [Phase 1]
Phase 1 pediatric trial of interleukin-15 and interleukin-21 armored glypican-3–specific CAR T cells for solid tumors, including liver-origi…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas [Phase 1]
Phase 1 study evaluating CD45RA+ depleted haploidentical stem cell transplantation in children with relapsed or refractory solid tumors and …
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE) [Phase 1]
Phase 1 SABRE trial evaluating selective antigen-specific T cells and CAR T cells in relapsed/refractory embryonal tumors, including rhabdom…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Biomarkers of Resiliency In Childhood Cancer Surgery
Clinical trial update from Mayo Clinic on biomarkers of resiliency in pediatric cancer surgery, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors [Phase 1]
This is an update on a Phase 1 trial of interleukin-15 armored GPC3-specific CAR-T cells for pediatric solid tumors, with results posted and…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors [Phase 2]
A Phase 2 clinical trial evaluating selinexor in Wilms tumor, rhabdoid tumors, and other solid tumors is currently recruiting at Memorial Sl…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
Phase 1 clinical trial update describing B7H3-targeted CAR T-cell therapy for recurrent/refractory pediatric solid tumors, including several…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
A Phase 1 trial update for EGFR806 CAR T cell immunotherapy in pediatric and young adult patients with recurrent/refractory solid tumors; th…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial [Phase 2]
This update reports on a Phase 2 pediatric MATCH trial evaluating selpercatinib for patients with activating RET gene alterations across adv…
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CLINICAL_TRIALS research · 2025-11-03Clinical Trial Update: Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells [Phase 1]
Phase 1 clinical trial evaluating GPC3-targeted CAR T cells armored with IL-15 and IL-21 for GPC3-positive solid tumors; currently recruitin…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating larotrectinib in patients with NTRK gene fusions has posted results; the study remains active but n…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Vascular Thrombus Involvement in Nephroblastoma
A clinical trial evaluating Wilms tumor (nephroblastoma) with inferior vena cava thrombosis has completed. The update notes the status as CO…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial [Phase 2]
Phase 2 pediatric MATCH trial results for Tipifarnib in HRAS-altered solid tumors and histiocytic disorders; the study has posted results an…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Clinical Trial for Patients With a Stage IV Childhood Renal Tumor, Comparing Upfront Vincristine, Actinomycin-D and Doxorubicin (Standard Arm) With Upfront Vincristine, Carboplatin and Etoposide (Experimental Arm) [Phase 3]
This Phase 3 trial update outlines a study in stage IV childhood renal tumors comparing upfront vincristine, actinomycin-D, and doxorubicin …