Von Hippel-lindau Disease
📧 Sign up to get email alerts when something new happens for Von Hippel-lindau Disease.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043) [Phase 3]
Extension study update for participants in Phase 3 trials of Belzutifan (MK-6482-043 / LITESPARK-043) with ongoing recruitment.
-
CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Use of Tracking Devices to Locate Abnormalities During Invasive Procedures [NA]
NIH-sponsored clinical trial update describes a study evaluating tracking devices to locate abnormalities during invasive procedures, with e…
-
CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015) [Phase 2]
This Phase 2 trial update covers belzutifan (MK-6482) for advanced pheochromocytoma/paraganglioma, pancreatic neuroendocrine tumors, von Hip…
-
CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors [Phase 2]
This entry describes a Phase 2 clinical trial on the natural history and management of Von Hippel-Lindau–associated pancreatic neuroendocrin…
-
CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Phase 2 Study of Belzutifan (PT2977, MK-6482) for the Treatment of Von Hippel Lindau (VHL) Disease-Associated Renal Cell Carcinoma (RCC) (MK-6482-004) [Phase 2]
Phase 2 clinical trial update for belzutifan (PT2977, MK-6482) in Von Hippel-Lindau disease-associated renal cell carcinoma; the study (NCT0…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders
An NCI-sponsored clinical trial evaluating Von Hippel-Lindau–associated renal and other urologic malignancies, including manifestations, dia…
-
CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: National Eye Institute Biorepository for Retinal Diseases
This document is a clinical trial update announcing the National Eye Institute Biorepository for Retinal Diseases, which is currently recrui…
-
CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Study of Brain and Spinal Cord Tumor Growth and Cyst Development in Patients With Von Hippel Lindau Disease
Clinical trial update on a study of brain and spinal cord tumor growth and cyst development in Von Hippel-Lindau disease patients, currently…
-
CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: CAT-VHL Exploring the Role of Carbonic Anhydrase IX as Diagnostic and Theranostic Target in Von-Hippel Lindau Disease [Phase 2]
Phase 2 clinical trial CAT-VHL is investigating carbonic anhydrase IX as a diagnostic and theranostic target in Von Hippel-Lindau disease.
-
CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Retrospective Case Series of Trans-scleral Cryotherapy for Retinal Hemangioblastoma
This document reports a retrospective case-series evaluating trans-scleral cryotherapy for retinal hemangioblastoma in Von Hippel-Lindau dis…
-
CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Quality of Life, Psychological Impact, and Care-related Challenges in Patients Affected by Von Hippel-Lindau Syndrome.
This study investigates the quality of life, psychological impact, and care-related challenges faced by people with Von Hippel-Lindau diseas…
-
CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Institutional Registry of Rare Diseases
An institutional registry for rare diseases sponsored by Hospital Italiano de Buenos Aires is currently recruiting. The registry includes am…
-
EMA approval · 2026-01-13EMA Authorised: Welireg (belzutifan) — Merck Sharp & Dohme B.V.
The European Medicines Agency authorised Welireg (belzutifan) for renal cell carcinoma and von Hippel-Lindau disease, in the EU under condit…
-
CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Precision Medicine for Neurocutaneous Syndromes in Western China
A completed clinical trial from West China Hospital exploring precision medicine approaches for neurocutaneous syndromes, including NF1, TSC…
-
CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Data Collection Protocol for Patients With Von Hippel Lindau Disease
MD Anderson Cancer Center is conducting a data collection protocol for patients with Von Hippel-Lindau disease and is currently recruiting.
-
CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Real-World Effectiveness and Pharmacogenetics of Belzutifan in VHL Syndrome: The BELIEVE-VHL Trial [Phase 2]
Phase 2 BELIEVE-VHL trial is assessing real-world effectiveness and pharmacogenetics of belzutifan in Von Hippel-Lindau syndrome; recruitmen…
-
CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Promoting Stress Management and Resilience Among Individuals With Von Hippel- Lindau Disease [NA]
A clinical trial update indicates that Massachusetts General Hospital is enrolling by invitation to study stress management and resilience i…
-
CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Pazopanib Hydrochloride in Treating Patients With Von Hippel-Lindau Syndrome [Phase 2]
Phase 2 clinical trial evaluating pazopanib hydrochloride in patients with Von Hippel-Lindau syndrome has completed and results have been po…
-
CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: Overtaking Intra and Inter Tumoral Heterogeneity In Von Hippel-Lindau Related Renal Cancer
A clinical trial update for NCT06195150 on Von Hippel-Lindau related renal cancer (Clear Cell Renal Cell Carcinoma) at IRCCS San Raffaele, c…
-
EMA approval · 2024-12-13First medicine to treat rare genetic disorder causing cysts and tumours
The European Medicines Agency approved belzutifan (brand name Welireg) as the first medicine to treat von Hippel-Lindau disease and advanced…
-
CLINICAL_TRIALS withdrawal · 2024-11-29Clinical Trial Update: MSD Belzutifan PAS
The belzutifan trial for von Hippel-Lindau disease has been withdrawn.
-
CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: MK-3795 (PT2385) for the Treatment of Von Hippel-Lindau Disease-Associated Clear Cell Renal Cell Carcinoma (MK-3795-003) [Phase 2]
Phase 2 trial of MK-3795 (PT2385) for Von Hippel-Lindau–associated clear cell renal cell carcinoma has completed with results posted in 2024…
-
CLINICAL_TRIALS research · 2024-08-14Clinical Trial Update: A Study of HS-10516 in Patients With VHL Syndrome Associated Tumors [Phase 1]
Phase 1 trial update for HS-10516 in Von Hippel-Lindau-associated tumors, currently recruiting for VHL-deficient clear cell renal cell carci…
-
CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Contrast-enhanced Ultrasound as a Screening Tool for Kidney Cancer in Patients With Von-Hippel Lindau [Phase 2]
A Phase 2 trial assessing contrast-enhanced ultrasound for screening kidney cancer in patients with Von Hippel-Lindau disease has completed,…
-
CLINICAL_TRIALS research · 2024-05-06Clinical Trial Update: Visualizing Vascular Endothelial Growth Factor (VEGF) Producing Lesions in Von Hippel-Lindau Disease
This clinical trial update describes a completed University Medical Center Groningen study on visualizing VEGF-producing lesions associated …