Uveal Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Tebentafusp in Molecular Relapsed Disease (MRD) Melanoma [Phase 2]
Phase 2 clinical trial update for tebentafusp in molecularly relapsed melanoma shows an active but not recruiting study targeting both cutan…
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: Defactinib and VS-6766 for the Treatment of Patients With Metastatic Uveal Melanoma [Phase 2]
A Phase 2 trial evaluating the combination of defactinib and VS-6766 for metastatic uveal melanoma was terminated, with results posted.
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Adding IL-2 to Tebentafusp to Eradicate Cancer Progression [Phase 1, Phase 2]
Announced clinical trial evaluating adding interleukin-2 to tebentafusp to eradicate cancer progression in uveal melanoma, including metasta…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Adoptive Transfer of Tumor Infiltrating Lymphocytes for Metastatic Uveal Melanoma [Phase 2]
A Phase 2 clinical trial studying adoptive transfer of tumor-infiltrating lymphocytes for metastatic uveal melanoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Adjuvant Quisinostat in High-Risk Uveal Melanoma [Phase 2]
This document reports a Phase 2 adjuvant trial of quisinostat in high-risk uveal melanoma, which is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: Study of Immunotherapy Plus ADI-PEG 20 for the Treatment of Advanced Uveal Melanoma [Phase 1]
Phase 1 study evaluating the combination of immunotherapy with ADI-PEG 20 for advanced uveal melanoma has completed.
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Adjuvant Melatonin for Uveal Melanoma [Phase 3]
A Phase 3 clinical trial evaluating adjuvant melatonin for uveal melanoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Sitravatinib and Tislelizumab in Patients With Metastatic Uveal Melanoma With Liver Metastases. [Phase 2]
Phase 2 trial evaluating sitravatinib in combination with tislelizumab for metastatic uveal melanoma with liver metastases has completed; th…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Isolated Hepatic Perfusion in Combination With Ipilimumab and Nivolumab in Patients With Uveal Melanoma Metastases [Phase 1]
Phase 1 trial evaluating isolated hepatic perfusion in combination with ipilimumab and nivolumab for metastatic uveal melanoma to the liver;…
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: A Study of TBio-4101 (TIL) and Pembrolizumab in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study of TBio-4101 (TIL) with pembrolizumab in advanced solid tumors has been terminated; the trial includes multiple indications su…
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CLINICAL_TRIALS trial_result · 2025-03-03Clinical Trial Update: Phase 2 Trial to Evaluate Belzupacap Sarotalocan (AU-011) Via Suprachoroidal Administration in Subjects With Primary Indeterminate Lesions and Small Choroidal Melanoma [Phase 2]
Phase 2 study of AU-011 (Belzupacap Sarotalocan) delivered suprachoroidally in subjects with primary indeterminate lesions and small choroid…
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: Influence of Oral Treatment With Citicoline for the Prevention of Radiation Optic Neuropathy in Patients Treated for Uveal Melanomas With Proton Beam Therapy [NA]
This clinical trial update reports completion of a study evaluating whether oral citicoline can prevent radiation optic neuropathy in patien…
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Nivolumab Plus Relatlimab in Patients With Metastatic Uveal Melanoma [Phase 2]
A Phase 2 trial evaluating the combination of nivolumab and relatlimab in metastatic uveal melanoma has completed, with results posted in Fe…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Transarterial Radioembolisation in Comparison to Transarterial Chemoembolisation in Uveal Melanoma Liver Metastasis [Phase 2]
A Phase 2 clinical trial comparing transarterial radioembolization with yttrium-90 microspheres to transarterial chemoembolization for liver…
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: PHP in Combination With IPI1/NIVO3 Compared to IPI3/NIVO1 Only in Patients With Uveal Melanoma Liver Metastases [Phase 3]
Phase 3 trial evaluating PHP in combination with ipilimumab and nivolumab versus ipilimumab and nivolumab alone in patients with uveal melan…
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Melanoma Vaccine Against Neoantigen and Shared Antigens by CD40 Activation and TLR Agonists In Patients With Melanoma (Including Ocular Melanoma) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating an investigational melanoma vaccine that uses CD40 activation and TLR agonists to target neoantigens and…
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FDA approval · 2024-06-27FDA Approved: KIMMTRAK — Supplemental Application (Immunocore Commercial LLC)
FDA approved a supplemental Biologics License Application for KIMMTRAK (tebentafusp) from Immunocore Commercial LLC.
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: FHD-286 in Subjects With Metastatic Uveal Melanoma [Phase 1]
The Phase 1 study of FHD-286 in metastatic uveal melanoma has been terminated.
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: Study in Subjects With Small Primary Choroidal Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial in subjects with small primary choroidal melanoma (uveal/ocular melanoma) has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-01-26Clinical Trial Update: The Scandinavian Randomized Controlled Trial of Isolated Hepatic Perfusion for Uveal Melanoma Liver Metastases [Phase 3]
Phase 3 trial update on isolated hepatic perfusion for liver metastases from uveal melanoma has completed.
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CLINICAL_TRIALS trial_result · 2023-12-21Clinical Trial Update: An Open-Label Expanded Access Study of the Melphalan/Hepatic Delivery System (HDS) in Patients With Hepatic Dominant Ocular Melanoma [Phase 3]
Open-label expanded access study update for the Melphalan/Hepatic Delivery System in hepatic-dominant ocular/uveal melanoma (Phase 3).
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CLINICAL_TRIALS trial_result · 2023-12-08Clinical Trial Update: Efficacy Study of Pembrolizumab With Entinostat to Treat Metastatic Melanoma of the Eye [Phase 2]
Phase 2 trial examining pembrolizumab with entinostat for metastatic uveal melanoma has completed.
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CLINICAL_TRIALS trial_result · 2023-12-06Clinical Trial Update: Crizotinib in High-Risk Uveal Melanoma Following Definitive Therapy [Phase 2]
Phase 2 trial evaluating crizotinib in high-risk uveal melanoma after definitive therapy has completed and results posted.
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CLINICAL_TRIALS trial_result · 2023-11-29Clinical Trial Update: Ipilimumab and Nivolumab With Immunoembolization in Treating Participants With Metastatic Uveal Melanoma in the Liver [Phase 2]
Phase 2 trial evaluating ipilimumab and nivolumab with immunoembolization for metastatic uveal melanoma to the liver has completed and resul…
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CLINICAL_TRIALS trial_result · 2023-11-22Clinical Trial Update: Study of PAC-1 and Entrectinib for Patients With Metastatic Uveal Melanoma [Phase 1, Phase 2]
Phase 1/2 clinical trial of PAC-1 in combination with entrectinib for metastatic uveal melanoma was terminated; results posted in 2023.