Uveal Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Different Doses of BI-1607 in Combination With Pembrolizumab and Ipilimumab, in Participants With Unresectable or Metastatic Melanoma [Phase 1, Phase 2]
This document updates on a Phase 1/2 clinical trial assessing different doses of BI-1607 in combination with pembrolizumab and ipilimumab fo…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors
This is a screening study by TScan Therapeutics to collect samples for tumor-associated antigens, HLA typing, and HLA loss of heterozygosity…
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CLINICAL_TRIALS trial_result · 2025-11-14Clinical Trial Update: SIR-Spheres® 90Y Microspheres Treatment of Uveal Melanoma Metastasized to Liver [Phase 2]
Phase 2 trial evaluating SIR-Spheres 90Y resin microspheres for liver metastases from uveal melanoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2025-10-23Clinical Trial Update: Taxoprexin® Treatment for Advanced Eye Melanoma [Phase 2]
Phase 2 trial update reports completion of Taxoprexin studies for advanced eye melanoma; the excerpt does not include efficacy or safety res…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: Intrahepatic Delivery of SD-101 by Pressure-Enabled Regional Immuno-oncology (PERIO), With Checkpoint Blockade in Adults With Metastatic Uveal Melanoma [Phase 1]
Phase 1 trial evaluating intrahepatic delivery of SD-101 with checkpoint blockade for metastatic uveal melanoma in the liver has been termin…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Stereotactic Body Radiation Therapy and Aflibercept in Treating Patients With Uveal Melanoma [Phase 2]
A Phase 2 trial evaluating stereotactic body radiation therapy with aflibercept for uveal melanoma has been terminated, and results have bee…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit [Phase 1]
Phase 1 study evaluating NN3201, a c-Kit targeted antibody-drug conjugate, in advanced and/or metastatic solid tumors expressing c-Kit; curr…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Hepatic Arterial Infusion of Autologous Tumor Infiltrating Lymphocytes in Patients With Melanoma and Liver Metastases [Phase 1]
Phase 1 trial evaluating hepatic arterial infusion of autologous tumor-infiltrating lymphocytes in patients with metastatic melanoma to the …
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Communicating With Patients on Cancer Resistance to Treatment: the Development of a Communication Tool. (HECTOR) [NA]
The document reports the completion of a study to develop a patient communication tool (HECTOR) for discussing cancer treatment resistance, …
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Evaluation Interest of the Circulating Tumor DNA Dosage in Patient With Hepatic Metastatic Uveal Melanoma Candidate to Complete Resection (ct DNA R0) [NA]
A completed clinical trial sponsored by Institut Curie evaluated circulating tumor DNA levels as a biomarker in patients with hepatic metast…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Locoregional or Systemic Administration of Autologous Tumor Infiltrating Lymphocytes in Patients With Metastatic Melanoma [Phase 1]
A Phase 1 clinical trial is evaluating locoregional or systemic administration of autologous tumor-infiltrating lymphocytes in patients with…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Melphalan Chemoreduction for Ocular Melanoma [Phase 1, Phase 2]
Ongoing Phase 1/Phase 2 clinical trial evaluating melphalan chemoreduction for uveal melanoma, currently enrolling by invitation.
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: PHP and Immunotherapy in Metastasized UM [Phase 1, Phase 2]
Phase 1/2 trial evaluating PHP in combination with immunotherapy for metastatic uveal melanoma; the study is currently active but not recrui…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Early Integration of Supportive Care for Metastatic Uveal Melanoma Patients (EarlyTogether) [NA]
Clinical trial update announcing the completion of the EarlyTogether study evaluating early integration of supportive care for patients with…
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FDA approval · 2025-09-04FDA Approved: HEPZATO KIT — Supplemental Application (Delcath Systems, Inc.)
FDA approved a supplemental application for Hepzato Kit (melphalan hydrochloride injection, lyophilized powder, for solution) from Delcath S…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Follow-up of Patients With Uveal Melanoma Adapted to the Risk of Relapse (SALOME) [NA]
This entry describes the SALOME clinical trial studying follow-up of patients with uveal melanoma to adapt to relapse risk; the study is cur…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: A Prospective Natural History Study in Uveal Melanoma
This clinical trial update describes a prospective natural history study in patients with uveal melanoma, currently active and not recruitin…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: Single Arm Trial of Tumor-Treating Fields in Combination With Nivolumab and Ipilimumab in Metastatic Uveal Melanoma [Phase 1]
A Phase 1, single-arm trial evaluating tumor-treating fields in combination with nivolumab and ipilimumab for metastatic uveal melanoma has …
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Study of the Activity of PD-1 Inhibitors in Metastatic Uveal Melanoma
This completed clinical trial evaluated the activity of PD-1 inhibitors in metastatic uveal melanoma.
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Endoresection of the Tumor Scar or Transpupillary Thermotherapy for the Treatment of Large Uveal Melanomas (Endoresection-Laser) [NA]
A completed clinical trial evaluating endoresection or transpupillary thermotherapy for large uveal melanomas, sponsored by Institut Curie.
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 study of APG-115 alone or with pembrolizumab in metastatic melanoma and other advanced solid tumors; the trial is currently active…
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: Transarterial Chemoembolization for the Treatment of Uveal Melanoma With Liver Metastases [Phase 2]
Phase 2 clinical trial update on transarterial chemoembolization for uveal melanoma with liver metastases; the study is currently active but…
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: Lenvatinib Plus Pembrolizumab In Patients With Immune Checkpoint Inhibitor Naïve Metastatic Uveal Melanoma [Phase 2]
Phase 2 trial evaluating lenvatinib plus pembrolizumab in immune checkpoint inhibitor–naïve patients with metastatic uveal melanoma. Results…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N) [Phase 1]
ClinicalTrials.gov entry updates the Phase 1 study of C7R-GD2.CART cells for relapsed or refractory GD2-positive cancers, including neurobla…
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas [Phase 1, Phase 2]
A Phase I/II clinical trial evaluating DYP688 in patients with metastatic uveal melanoma and other GNAQ/11-mutant melanomas; the study is cu…