Uveal Melanoma
📧 Sign up to get email alerts when something new happens for Uveal Melanoma.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: Adjuvant Tebentafusp in High Risk Ocular Melanoma [Phase 3]
This update notes ongoing Phase 3 recruitment for adjuvant tebentafusp in high-risk uveal melanoma, sponsored by the European Organisation f…
-
CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: IKKb-matured, RNA-loaded Dendritic Cells for Metastasised Uveal Melanoma [Phase 1]
A Phase 1 study evaluating an IKKβ-matured, RNA-loaded dendritic cell therapy for metastatic uveal melanoma has completed. The trial investi…
-
CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma [Phase 3]
Phase 3 randomized trial in recruitment evaluating Belzupacap Sarotalocan (AU-011) versus sham control for primary indeterminate lesions or …
-
CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Safety and Preliminary Efficacy of MBS8(1V270) in Cancer Patients With Advanced Solid Tumours [Phase 1]
Phase 1 study of the investigational therapy MBS8(1V270) evaluating safety and preliminary efficacy in patients with advanced solid tumors, …
-
CLINICAL_TRIALS other · 2026-02-27Clinical Trial Update: Tebentafusp in HLA-A*0201 Positive Previously Untreated Metastatic Uveal Melanoma [Phase 2]
This document provides an update on a Phase 2 trial of tebentafusp in HLA-A*0201 positive patients with previously untreated metastatic uvea…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Study of Tebentafusp and Radioembolization in the Treatment of Metastatic Uveal Melanoma [Phase 2]
A Phase 2 clinical trial update assessing tebentafusp in combination with radioembolization for metastatic uveal melanoma, including liver m…
-
CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Choroidal Melanoma Patient-Reported Outcome Study (CM-PRO) in a Subset of AU-011-301 (CoMpass) Subjects
A patient-reported outcome study (CM-PRO) is being conducted in a subset of AU-011-301 (CoMpass) trial participants, with recruitment ongoin…
-
CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Neoadjuvant Darovasertib in Primary Uveal Melanoma [Phase 3]
A Phase 3 neoadjuvant trial of darovasertib for primary uveal melanoma is currently recruiting.
-
CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Study Multicentre Evaluating the Effectiveness and Toxicity Sorafenib (Nexavar®) in Adult Patients With Uveal Melanoma and Metastatic Dissemination [Phase 2]
A Phase 2 multicenter study evaluating the effectiveness and toxicity of Sorafenib (Nexavar) in adults with uveal melanoma and metastatic di…
-
CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating IDE196 (darovasertib) in combination with crizotinib as first-line therapy for metastatic uveal melano…
-
CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, or Dedifferentiated Liposarcoma [Phase 1]
This Phase 1 study evaluates LN-144 or LN-145 in people with advanced uveal melanoma, undifferentiated pleomorphic sarcoma, dedifferentiated…
-
CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Modified Virus VSV-IFNbetaTYRP1 in Treating Patients With Stage III-IV Melanoma [Phase 1]
Phase 1 trial of the modified virus VSV-IFNbetaTYRP1 in stage III-IV melanoma was terminated.
-
CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Dendritic Cells Plus Autologous Tumor RNA in Uveal Melanoma [Phase 3]
Phase 3 clinical trial evaluating dendritic cells combined with autologous tumor RNA for uveal melanoma has completed.
-
CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions [Phase 1, Phase 2]
A Phase 1/2 study evaluating darovasertib (IDE196), a PKC inhibitor, in patients with solid tumors harboring GNAQ/GNA11 mutations or PRKC fu…
-
CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: A Randomised Phase II Study of Roginolisib in Patients With Advanced/Metastatic Uveal Melanoma [Phase 2]
Phase II clinical trial update for Roginolisib in advanced/metastatic uveal melanoma; the study is active but not currently recruiting.
-
CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: A Phase 1 Study of [225Ac]-FPI-1434 Injection [Phase 1]
A Phase 1 study of [225Ac]-FPI-1434 injection sponsored by Fusion Pharmaceuticals has been terminated.
-
CLINICAL_TRIALS trial_result · 2025-12-26Clinical Trial Update: Study of LVGN3616 and LVGN6051±LVGN7409 in Combination With Nab-Paclitaxel or Bevacizumab and Cyclophosphamide in Metastatic Solid Tumors [Phase 1]
Phase 1 trial evaluating LVGN3616 and LVGN6051±LVGN7409 with nab-paclitaxel or bevacizumab and cyclophosphamide in various metastatic solid …
-
CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas. [Phase 1]
This is a Phase 1 dose-escalation and expansion study evaluating intratumoral ONM-501 alone and in combination with cemiplimab in patients w…
-
CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Dexamethasone Implant for Retinal Detachment in Uveal Melanoma [Phase 1]
A Phase 1 clinical trial evaluating a dexamethasone intravitreal implant for exudative retinal detachment associated with uveal melanoma has…
-
EMA approval · 2025-12-09EMA Authorised: Kimmtrak (tebentafusp) — Immunocore Ireland Limited
EMA authorised Kimmtrak (tebentafusp) from Immunocore Ireland Limited for uveal melanoma, signaling EU approval of this first-in-class thera…
-
CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma [Phase 2]
Phase 2 clinical trial evaluating cemiplimab plus ziv-aflibercept for metastatic uveal melanoma is currently recruiting.
-
CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the safety and efficacy of IOV-3001 in adults with advanced melanoma who will receive lifileucel; t…
-
CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Evaluation of the Safety, Efficacy, and Pharmacokinetics of NBM-BMX in Patients With Metastatic Uveal Melanoma [Phase 1, Phase 2]
This clinical trial update describes the ongoing Phase 1/2 study of NBM-BMX in metastatic uveal melanoma, including safety, efficacy, and ph…
-
CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Tebentafusp-tebn With LDT in Metastatic UM [Phase 1, Phase 2]
Phase 1/Phase 2 trial of tebentafusp-tebn with LDT in metastatic uveal melanoma is currently recruiting.
-
CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Efficacy and Safety of Pembrolizumab in Combination With Lenvatinib in Metastatic Uveal MElanoma Patients (PLUME) [Phase 2]
This clinical trial update reports on a Phase 2 study evaluating pembrolizumab in combination with lenvatinib for efficacy and safety in pat…